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ATP13A2 ATP13A2 IL13 IL13 RAB3A RAB3A STAM STAM RAB3D RAB3D CHMP2A CHMP2A RAB27B RAB27B RAB9A RAB9A CACNA1B CACNA1B CD177 CD177 SYT2 SYT2 UNC13D UNC13D RAB27A RAB27A CACNA1H CACNA1H CACNA1I CACNA1I STXBP5 STXBP5 CADPS CADPS ITGAM ITGAM EXPH5 EXPH5 KIAA0100 KIAA0100 SLC4A8 SLC4A8 PLA2G3 PLA2G3 HYAL3 HYAL3 LOC103068503 LOC103068503 SYT1 SYT1 FGB FGB RAB15 RAB15 RAB2B RAB2B CFTR CFTR LOC103083537 LOC103083537 VPS4A VPS4A SCAMP5 SCAMP5 CACNB2 CACNB2 SNX4 SNX4 CDK5R2 CDK5R2 SYK SYK ADORA2B ADORA2B CADPS2 CADPS2 LOC103071181 LOC103071181 CD160 CD160 STXBP1 STXBP1 RAB5A RAB5A CNR1 CNR1 CACNA1A CACNA1A VAMP8 VAMP8 CDK5 CDK5 SYTL4 SYTL4 ZP3 ZP3 STX1A STX1A RAB7A RAB7A SNF8 SNF8 LAMP1 LAMP1 VSNL1 VSNL1 VPS4B VPS4B SDC1 SDC1 TSG101 TSG101 SPHK2 SPHK2 NLGN1 NLGN1 LOC103088397 LOC103088397 HGS HGS CACNB4 CACNB4 AP1G1 AP1G1 F2RL1 F2RL1 FGR FGR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1174 aa)
IL13Interleukin-13. (132 aa)
RAB3ARas-related protein Rab-3A. (220 aa)
STAMSignal transducing adapter molecule 1. (507 aa)
RAB3DRas-related protein Rab-3D. (219 aa)
CHMP2ACharged multivesicular body protein 2a. (222 aa)
RAB27BRas-related protein Rab-27B. (126 aa)
RAB9ARas-related protein Rab-9A. (201 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2261 aa)
CD177LOW QUALITY PROTEIN: CD177 antigen. (449 aa)
SYT2Synaptotagmin-2 isoform X1. (422 aa)
UNC13DProtein unc-13 homolog D. (1090 aa)
RAB27ARas-related protein Rab-27A. (221 aa)
CACNA1HLOW QUALITY PROTEIN: voltage-dependent T-type calcium channel subunit alpha-1H. (2346 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2110 aa)
STXBP5LOW QUALITY PROTEIN: syntaxin-binding protein 5. (1154 aa)
CADPSCalcium-dependent secretion activator 1 isoform X6. (1348 aa)
ITGAMIntegrin alpha-M; Belongs to the integrin alpha chain family. (1152 aa)
EXPH5LOW QUALITY PROTEIN: exophilin-5. (1979 aa)
KIAA0100UPF0378 protein KIAA0100 homolog. (2233 aa)
SLC4A8Anion exchange protein. (1092 aa)
PLA2G3Group 3 secretory phospholipase A2. (516 aa)
HYAL3Hyaluronidase. (513 aa)
LOC103068503LOW QUALITY PROTEIN: fibrinogen gamma-B chain-like. (445 aa)
SYT1Synaptotagmin-1 isoform X1. (422 aa)
FGBFibrinogen beta chain isoform X1. (488 aa)
RAB15Ras-related protein Rab-15. (212 aa)
RAB2BRas-related protein Rab-2B isoform X1. (216 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
LOC103083537Interleukin-13-like. (81 aa)
VPS4AVacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (437 aa)
SCAMP5Secretory carrier-associated membrane protein. (330 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (651 aa)
SNX4Sorting nexin-4. (450 aa)
CDK5R2Cyclin-dependent kinase 5 activator. (369 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (333 aa)
CADPS2Calcium-dependent secretion activator 2. (1190 aa)
LOC103071181Synaptotagmin-10-like. (424 aa)
CD160LOW QUALITY PROTEIN: CD160 molecule. (177 aa)
STXBP1Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
RAB5ARas-related protein Rab-5A isoform X1. (215 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2295 aa)
VAMP8Vesicle-associated membrane protein 8. (99 aa)
CDK5Cyclin-dependent kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
SYTL4Synaptotagmin-like protein 4. (672 aa)
ZP3Zona pellucida sperm-binding protein 3. (421 aa)
STX1Asyntaxin-1A; Belongs to the syntaxin family. (288 aa)
RAB7ARas-related protein Rab-7a. (207 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
LAMP1Lysosome-associated membrane glycoprotein 1. (414 aa)
VSNL1Visinin-like protein 1 isoform X1. (208 aa)
VPS4BVacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (443 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
TSG101Tumor susceptibility gene 101 protein. (391 aa)
SPHK2Sphingosine kinase 2 isoform X1. (655 aa)
NLGN1Neuroligin-1 isoform X1. (863 aa)
LOC103088397Vesicle-associated membrane protein 7-like isoform X1; Belongs to the synaptobrevin family. (220 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (519 aa)
AP1G1AP-1 complex subunit gamma. (829 aa)
F2RL1Proteinase-activated receptor 2. (397 aa)
FGRTyrosine-protein kinase. (537 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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