STRINGSTRING
MBOAT7 MBOAT7 MTMR8 MTMR8 FAM102A FAM102A TPTE2 TPTE2 CCDC180 CCDC180 MTMR6 MTMR6 PIP5KL1 PIP5KL1 TTC7B TTC7B DPM2 DPM2 LCLAT1 LCLAT1 PIK3C2B PIK3C2B PIGP PIGP SH3YL1 SH3YL1 FGF2 FGF2 PTEN PTEN INPP5F INPP5F PIGG PIGG PIP4K2C PIP4K2C SOCS2 SOCS2 FAM126B FAM126B SMG1 SMG1 LOC103078601 LOC103078601 MTMR9 MTMR9 TMEM150A TMEM150A PGAP1 PGAP1 PIGA PIGA SOCS7 SOCS7 PGAP3 PGAP3 INPP1 INPP1 PIK3CA PIK3CA PIGZ PIGZ PIGT PIGT INPP4A INPP4A LOC103076489 LOC103076489 PIP5K1B PIP5K1B PIK3CB PIK3CB LOC103082712 LOC103082712 ITPKB ITPKB PLEK PLEK PIGX PIGX INPP5D INPP5D IP6K1 IP6K1 ATM ATM DPM1 DPM1 CSF1R CSF1R CDS1 CDS1 LOC103076855 LOC103076855 PLCD4 PLCD4 SOCS4 SOCS4 FIG4 FIG4 ATG14 ATG14 IP6K2 IP6K2 LOC103077129 LOC103077129 PLCH2 PLCH2 PSORS1C2 PSORS1C2 PIGC PIGC PI4K2B PI4K2B SLA2 SLA2 PIGU PIGU BECN1 BECN1 SYNJ1 SYNJ1 FAM126A FAM126A PDGFRB PDGFRB PIGY PIGY PIGH PIGH MTMR4 MTMR4 PI4KA PI4KA PIK3C2A PIK3C2A FAM102B FAM102B OCRL OCRL PIGS PIGS CISH CISH PLCB1 PLCB1 PIK3R3 PIK3R3 PYURF PYURF LPGAT1 LPGAT1 PIK3CD PIK3CD LOC103072007 LOC103072007 PLA2G3 PLA2G3 SYNJ2 SYNJ2 MTMR2 MTMR2 MTM1 MTM1 LOC103070538 LOC103070538 PLCG2 PLCG2 INPP5A INPP5A MTMR1 MTMR1 PIP4K2A PIP4K2A LOC103075712 LOC103075712 INPP5J INPP5J UVRAG UVRAG MTMR12 MTMR12 CDIPT CDIPT INPP5B INPP5B PIK3CG PIK3CG LOC103085051 LOC103085051 PIGQ PIGQ INPP5K INPP5K PIGW PIGW DGKE DGKE GPLD1 GPLD1 PIK3C2G PIK3C2G PIK3R1 PIK3R1 LOC103080488 LOC103080488 PIK3R6 PIK3R6 BPNT1 BPNT1 DPM3 DPM3 PIGB PIGB PIGO PIGO CWH43 CWH43 PIGK PIGK PI4K2A PI4K2A ITPKC ITPKC TMEM246 TMEM246 MTMR10 MTMR10 PIGN PIGN TMEM55A TMEM55A MTMR7 MTMR7 PIGF PIGF SOCS5 SOCS5 PIP5K1A PIP5K1A PIP5K1C PIP5K1C INPP5E INPP5E PIGV PIGV PLCB2 PLCB2 PI4KB PI4KB PLCB3 PLCB3 IP6K3 IP6K3 ITPKA ITPKA SLC27A1 SLC27A1 PIK3R2 PIK3R2 TTC7A TTC7A SOCS3 SOCS3 LOC103083783 LOC103083783 PIGM PIGM PIGL PIGL PLCD1 PLCD1 SOCS6 SOCS6 IMPA2 IMPA2 MTMR3 MTMR3 PIKFYVE PIKFYVE IMPA1 IMPA1 IMPAD1 IMPAD1 PGAP2 PGAP2 PIK3C3 PIK3C3 PIK3R4 PIK3R4 TMEM55B TMEM55B PLCG1 PLCG1 INPPL1 INPPL1 SOCS1 SOCS1 SACM1L SACM1L PIP4K2B PIP4K2B INPP4B INPP4B VAC14 VAC14 MPPE1 MPPE1 MTMR11 MTMR11 GPAA1 GPAA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MBOAT7Lysophospholipid acyltransferase 7; Belongs to the membrane-bound acyltransferase family. (472 aa)
MTMR8LOW QUALITY PROTEIN: myotubularin related protein 8. (308 aa)
FAM102AProtein FAM102A. (384 aa)
TPTE2Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like. (519 aa)
CCDC180LOW QUALITY PROTEIN: coiled-coil domain containing 180. (1253 aa)
MTMR6Myotubularin-related protein 6. (621 aa)
PIP5KL1Phosphatidylinositol 4-phosphate 5-kinase-like protein 1. (396 aa)
TTC7BTetratricopeptide repeat protein 7B isoform X1. (871 aa)
DPM2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (138 aa)
LCLAT1Lysocardiolipin acyltransferase 1 isoform X1. (376 aa)
PIK3C2BPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
PIGPPhosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. (149 aa)
SH3YL1SH3 domain-containing YSC84-like protein 1. (342 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
INPP5FPhosphatidylinositide phosphatase SAC2. (1134 aa)
PIGGGPI ethanolamine phosphate transferase 2 isoform X1. (983 aa)
PIP4K2CPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma isoform X1. (421 aa)
SOCS2Suppressor of cytokine signaling 2 isoform X1. (198 aa)
FAM126BProtein FAM126B. (530 aa)
SMG1Serine/threonine-protein kinase SMG1 isoform X1; Belongs to the PI3/PI4-kinase family. (3658 aa)
LOC103078601Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y-like. (58 aa)
MTMR9Myotubularin-related protein 9. (549 aa)
TMEM150ALOW QUALITY PROTEIN: transmembrane protein 150A. (302 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
PIGAPhosphatidylinositol N-acetylglucosaminyltransferase subunit A isoform X1. (485 aa)
SOCS7Suppressor of cytokine signaling 7. (677 aa)
PGAP3Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (320 aa)
INPP1Inositol polyphosphate 1-phosphatase isoform X1. (402 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
PIGZMannosyltransferase. (592 aa)
PIGTGPI transamidase component PIG-T isoform X1. (578 aa)
INPP4AType I inositol 3,4-bisphosphate 4-phosphatase isoform X1. (989 aa)
LOC103076489Uncharacterized protein C2orf66 homolog. (127 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1. (540 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
LOC103082712Protein preY, mitochondrial-like. (115 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (942 aa)
PLEKPleckstrin. (350 aa)
PIGXPhosphatidylinositol-glycan biosynthesis class X protein. (395 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1187 aa)
IP6K1Kinase; Belongs to the inositol phosphokinase (IPK) family. (441 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa)
DPM1Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (260 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (456 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa)
LOC103076855Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y-like. (71 aa)
PLCD4Phosphoinositide phospholipase C. (763 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
FIG4Polyphosphoinositide phosphatase. (907 aa)
ATG14Beclin 1-associated autophagy-related key regulator. (414 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (425 aa)
LOC103077129Protein preY, mitochondrial-like. (114 aa)
PLCH2Phosphoinositide phospholipase C. (1707 aa)
PSORS1C2LOW QUALITY PROTEIN: psoriasis susceptibility 1 candidate gene 2 protein homolog. (154 aa)
PIGCLOW QUALITY PROTEIN: phosphatidylinositol N-acetylglucosaminyltransferase subunit C. (299 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2-beta. (498 aa)
SLA2Src-like-adapter 2. (276 aa)
PIGUPhosphatidylinositol glycan anchor biosynthesis class U protein isoform X1. (435 aa)
BECN1Beclin-1 isoform X1. (448 aa)
SYNJ1Synaptojanin-1 isoform X1. (1600 aa)
FAM126AHyccin. (521 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
PIGYPhosphatidylinositol N-acetylglucosaminyltransferase subunit Y. (71 aa)
PIGHPhosphatidylinositol N-acetylglucosaminyltransferase subunit H. (188 aa)
MTMR4Myotubularin-related protein 4 isoform X1. (1210 aa)
PI4KAPhosphatidylinositol 4-kinase alpha isoform X1; Belongs to the PI3/PI4-kinase family. (2098 aa)
PIK3C2APhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; Belongs to the PI3/PI4-kinase family. (1688 aa)
FAM102BProtein FAM102B-like. (361 aa)
OCRLInositol polyphosphate 5-phosphatase OCRL-1 isoform X1. (904 aa)
PIGSGPI transamidase component PIG-S isoform X1. (555 aa)
CISHCytokine-inducible SH2-containing protein. (254 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
PYURFProtein preY, mitochondrial. (114 aa)
LPGAT1acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1. (370 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
LOC103072007Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit-like. (327 aa)
PLA2G3Group 3 secretory phospholipase A2. (516 aa)
SYNJ2Synaptojanin-2. (1475 aa)
MTMR2Myotubularin-related protein 2 isoform X1. (643 aa)
MTM1Myotubularin isoform X1. (603 aa)
LOC103070538Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y-like. (71 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
INPP5AType I inositol 1,4,5-trisphosphate 5-phosphatase. (412 aa)
MTMR1Myotubularin-related protein 1 isoform X1. (665 aa)
PIP4K2APhosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1. (406 aa)
LOC103075712Protein preY, mitochondrial-like. (108 aa)
INPP5JPhosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1. (980 aa)
UVRAGUV radiation resistance-associated gene protein isoform X1. (699 aa)
MTMR12Myotubularin-related protein 12 isoform X2. (747 aa)
CDIPTCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (251 aa)
INPP5BLOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase. (1208 aa)
PIK3CGLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1126 aa)
LOC103085051Inositol polyphosphate 5-phosphatase OCRL-1-like. (230 aa)
PIGQPhosphatidylinositol N-acetylglucosaminyltransferase subunit Q. (581 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform X1. (450 aa)
PIGWPhosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (502 aa)
DGKEDiacylglycerol kinase. (602 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D isoform X1. (839 aa)
PIK3C2GPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform X1; Belongs to the PI3/PI4-kinase family. (1483 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
LOC103080488Coiled-coil domain-containing protein 180-like. (421 aa)
PIK3R6Phosphoinositide 3-kinase regulatory subunit 6. (756 aa)
BPNT13'(2'),5'-bisphosphate nucleotidase 1 isoform X1. (308 aa)
DPM3Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (92 aa)
PIGBMannosyltransferase. (539 aa)
PIGOGPI ethanolamine phosphate transferase 3. (1131 aa)
CWH43LOW QUALITY PROTEIN: PGAP2-interacting protein. (674 aa)
PIGKGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (395 aa)
PI4K2APhosphatidylinositol 4-kinase type 2-alpha. (493 aa)
ITPKCKinase; Belongs to the inositol phosphokinase (IPK) family. (647 aa)
TMEM246Transmembrane protein 246. (403 aa)
MTMR10Myotubularin-related protein 10. (772 aa)
PIGNGPI ethanolamine phosphate transferase 1. (931 aa)
TMEM55APhosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
MTMR7Myotubularin-related protein 7. (660 aa)
PIGFPhosphatidylinositol-glycan biosynthesis class F protein. (219 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (549 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (828 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (877 aa)
PIGVGPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (493 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1420 aa)
PI4KBPhosphatidylinositol 4-kinase beta isoform X1; Belongs to the PI3/PI4-kinase family. (816 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1230 aa)
IP6K3Kinase; Belongs to the inositol phosphokinase (IPK) family. (389 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
SLC27A1Long-chain fatty acid transport protein 1. (646 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
TTC7ATetratricopeptide repeat protein 7A. (760 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
LOC103083783CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (217 aa)
PIGMGPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (423 aa)
PIGLN-acetylglucosaminyl-phosphatidylinositol de-N-acetylase. (253 aa)
PLCD1Phosphoinositide phospholipase C. (721 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
IMPA2Inositol-1-monophosphatase. (288 aa)
MTMR3LOW QUALITY PROTEIN: myotubularin-related protein 3. (1205 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase isoform X1. (2097 aa)
IMPA1Inositol monophosphatase 1. (464 aa)
IMPAD1Inositol monophosphatase 3. (359 aa)
PGAP2post-GPI attachment to proteins factor 2 isoform X2. (339 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa)
TMEM55BPhosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (367 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
INPPL1LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1264 aa)
SOCS1Suppressor of cytokine signaling 1. (216 aa)
SACM1LPhosphatidylinositide phosphatase SAC1 isoform X1. (587 aa)
PIP4K2BPhosphatidylinositol 5-phosphate 4-kinase type-2 beta. (370 aa)
INPP4BType II inositol 3,4-bisphosphate 4-phosphatase. (925 aa)
VAC14Protein VAC14 homolog. (782 aa)
MPPE1Metallophosphoesterase 1. (426 aa)
MTMR11Myotubularin-related protein 11 isoform X1. (699 aa)
GPAA1Glycosylphosphatidylinositol anchor attachment 1 protein isoform X1. (622 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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