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HSP90B1 HSP90B1 LOC103090748 LOC103090748 WNT10B WNT10B PIK3CG PIK3CG SLC26A3 SLC26A3 PDXP PDXP P2RX5 P2RX5 P2RX3 P2RX3 INPP5K INPP5K P2RX1 P2RX1 ZFP36L1 ZFP36L1 P2RX2 P2RX2 NDUFS4 NDUFS4 AQP9 AQP9 ENPP1 ENPP1 HCN3 HCN3 IGFBP5 IGFBP5 LOC103089871 LOC103089871 PER1 PER1 WT1 WT1 KCNJ11 KCNJ11 LOC103074626 LOC103074626 HCN2 HCN2 SLC5A5 SLC5A5 RAP1B RAP1B AKAP9 AKAP9 EZR EZR AHR AHR RFC3 RFC3 TRPM4 TRPM4 TRPC3 TRPC3 RAPGEF3 RAPGEF3 DUOX1 DUOX1 CITED1 CITED1 NT5E NT5E DGKQ DGKQ KCNQ1 KCNQ1 AQP1 AQP1 LOC103085653 LOC103085653 DUOX2 DUOX2 HCN1 HCN1 LOC103088976 LOC103088976 CRHBP CRHBP CIB2 CIB2 P2RX6 P2RX6 FDX1 FDX1 VGF VGF P2RY12 P2RY12 LOC103077121 LOC103077121 KCNE1 KCNE1 SLC26A6 SLC26A6 ITPR2 ITPR2 RAPGEF2 RAPGEF2 LOC103085837 LOC103085837 ABCC9 ABCC9 P2RX7 P2RX7 PDE2A PDE2A P2RY6 P2RY6 SSH1 SSH1 CFTR CFTR RAP1A RAP1A P2RX4 P2RX4 DMTN DMTN AQP8 AQP8 PKD2 PKD2 AKAP6 AKAP6 GPD1 GPD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HSP90B1Endoplasmin. (803 aa)
LOC103090748Zinc finger protein 36, C3H1 type-like 1-like. (226 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
PIK3CGLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1126 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (759 aa)
PDXPPyridoxal phosphate phosphatase; Belongs to the HAD-like hydrolase superfamily. (296 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (450 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform X1. (450 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ZFP36L1Zinc finger protein 36, C3H1 type-like 1-like. (338 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (415 aa)
NDUFS4NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (175 aa)
AQP9Aquaporin-9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase family member 1. (925 aa)
HCN3Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3. (786 aa)
IGFBP5Insulin-like growth factor-binding protein 5. (271 aa)
LOC103089871Sulfate/thiosulfate import ATP-binding protein cysA-like. (208 aa)
PER1Period circadian protein homolog 1. (1273 aa)
WT1Wilms tumor protein isoform X1. (450 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11 isoform X1. (388 aa)
LOC103074626Tripartite motif-containing protein 16-like. (558 aa)
HCN2LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2. (904 aa)
SLC5A5Sodium/iodide cotransporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (642 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
AKAP9A-kinase anchor protein 9. (3874 aa)
EZREzrin isoform X1. (586 aa)
AHRLOW QUALITY PROTEIN: aryl hydrocarbon receptor. (847 aa)
RFC3Replication factor C subunit 3. (356 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1204 aa)
TRPC3Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (920 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
DUOX1LOW QUALITY PROTEIN: dual oxidase 1. (1549 aa)
CITED1Cbp/p300-interacting transactivator 1 isoform X1. (221 aa)
NT5E5'-nucleotidase isoform X1; Belongs to the 5'-nucleotidase family. (574 aa)
DGKQDiacylglycerol kinase. (937 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (580 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
LOC103085653Period circadian protein homolog 1-like. (220 aa)
DUOX2Dual oxidase 2 isoform X1. (1553 aa)
HCN1Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (876 aa)
LOC103088976Ras-related protein Rap-1b-like isoform X1. (165 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
CIB2Calcium and integrin-binding family member 2 isoform X1. (144 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (393 aa)
FDX1Adrenodoxin, mitochondrial. (193 aa)
VGFLOW QUALITY PROTEIN: VGF nerve growth factor inducible. (604 aa)
P2RY12LOW QUALITY PROTEIN: P2Y purinoceptor 12. (336 aa)
LOC103077121Oxytocin-neurophysin 1-like. (110 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (129 aa)
SLC26A6Solute carrier family 26 member 6. (761 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1483 aa)
LOC103085837Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4-like. (1200 aa)
ABCC9ATP-binding cassette sub-family C member 9 isoform X1. (1549 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
PDE2APhosphodiesterase. (941 aa)
P2RY6P2Y purinoceptor 6. (328 aa)
SSH1Protein phosphatase Slingshot homolog 1. (1039 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
DMTNDematin isoform X1. (405 aa)
AQP8Aquaporin-8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
PKD2LOW QUALITY PROTEIN: polycystin-2. (963 aa)
AKAP6A-kinase anchor protein 6. (2320 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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