STRINGSTRING
RIMS3 RIMS3 NTRK2 NTRK2 SHANK3 SHANK3 KMT2A KMT2A LGMN LGMN STX3 STX3 SORCS2 SORCS2 SRF SRF RIMS1 RIMS1 SLC8A2 SLC8A2 SNAP47 SNAP47 SYNPR SYNPR KRAS KRAS LOC103070587 LOC103070587 NPTN NPTN NFATC4 NFATC4 CALB1 CALB1 NSMF NSMF MECP2 MECP2 LOC103087287 LOC103087287 CBLN1 CBLN1 AGER AGER DLG4 DLG4 AKAP5 AKAP5 GIPC3 GIPC3 GRIA1 GRIA1 RASGRF1 RASGRF1 GIPC2 GIPC2 NETO1 NETO1 RAB3A RAB3A PSEN1 PSEN1 KCNJ10 KCNJ10 EPHB2 EPHB2 ANAPC2 ANAPC2 LRRTM2 LRRTM2 SERPINE2 SERPINE2 GRM5 GRM5 LOC103078014 LOC103078014 PRRT1 PRRT1 NPAS4 NPAS4 NCSTN NCSTN SYNGAP1 SYNGAP1 ITPKA ITPKA BAIAP2 BAIAP2 PAIP2 PAIP2 CALB2 CALB2 UNC13C UNC13C RGS14 RGS14 ITPR3 ITPR3 GRIN2D GRIN2D DBN1 DBN1 LOC103084253 LOC103084253 SLC4A10 SLC4A10 BAI1 BAI1 NRGN NRGN SHISA9 SHISA9 KCNB1 KCNB1 ADCY1 ADCY1 IGSF11 IGSF11 NR2E1 NR2E1 JPH4 JPH4 KAT2A KAT2A SLC24A1 SLC24A1 ADCY8 ADCY8 GRID2IP GRID2IP GRID2 GRID2 SYP SYP MAPK1 MAPK1 ERC2 ERC2 NF1 NF1 SNAP25 SNAP25 SYT12 SYT12 TNR TNR ABL1 ABL1 RASGRF2 RASGRF2 PICK1 PICK1 ATF4 ATF4 NCDN NCDN S100B S100B ZZEF1 ZZEF1 PRRT2 PRRT2 DRD2 DRD2 GRIN2B GRIN2B PLK2 PLK2 MPP2 MPP2 SYAP1 SYAP1 CLN3 CLN3 SHISA6 SHISA6 SYNGR1 SYNGR1 SHISA8 SHISA8 GRIN2A GRIN2A NOG NOG NEUROD2 NEUROD2 CPLX2 CPLX2 ARC ARC GRIK2 GRIK2 RIMS2 RIMS2 LRRTM1 LRRTM1 SQSTM1 SQSTM1 APP APP PTN PTN EPHA4 EPHA4 SCT SCT HRAS HRAS LOC103085844 LOC103085844 CRHR2 CRHR2 CX3CR1 CX3CR1 CHRDL1 CHRDL1 SHISA7 SHISA7 BRAF BRAF DGKI DGKI RELN RELN LOC103069787 LOC103069787 SLC24A2 SLC24A2 CDC20 CDC20 JPH3 JPH3 NEURL1 NEURL1 CDK5 CDK5 ERC1 ERC1 SCGN SCGN ABHD6 ABHD6 GIPC1 GIPC1 LZTS1 LZTS1 CNTN2 CNTN2 SORCS3 SORCS3 RAB5A RAB5A STXBP1 STXBP1 VGF VGF YWHAG YWHAG LOC103068707 LOC103068707 P2RX3 P2RX3 GRIN2C GRIN2C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIMS3Regulating synaptic membrane exocytosis protein 3. (308 aa)
NTRK2Tyrosine-protein kinase receptor. (366 aa)
SHANK3SH3 and multiple ankyrin repeat domains protein 3. (1586 aa)
KMT2AHistone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3974 aa)
LGMNLegumain. (434 aa)
STX3Syntaxin-3; Belongs to the syntaxin family. (289 aa)
SORCS2VPS10 domain-containing receptor SorCS2. (1049 aa)
SRFSerum response factor. (510 aa)
RIMS1Regulating synaptic membrane exocytosis protein 1-like isoform X1. (1678 aa)
SLC8A2Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
SNAP47LOW QUALITY PROTEIN: synaptosomal-associated protein 47. (491 aa)
SYNPRSynaptoporin isoform X1. (276 aa)
KRASGTPase KRas. (188 aa)
LOC103070587Tyrosine-protein kinase ABL1-like. (126 aa)
NPTNNeuroplastin isoform X1. (398 aa)
NFATC4Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (901 aa)
CALB1LOW QUALITY PROTEIN: calbindin. (263 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor isoform X2. (532 aa)
MECP2methyl-CpG-binding protein 2. (537 aa)
LOC103087287Angiotensin-converting enzyme. (1302 aa)
CBLN1Cerebellin-1. (193 aa)
AGERAdvanced glycosylation end product-specific receptor isoform X1. (421 aa)
DLG4Disks large homolog 4 isoform X1; Belongs to the MAGUK family. (754 aa)
AKAP5A-kinase anchor protein 5. (429 aa)
GIPC3PDZ domain-containing protein GIPC3. (318 aa)
GRIA1Glutamate receptor 1 isoform X1. (906 aa)
RASGRF1Ras-specific guanine nucleotide-releasing factor 1 isoform X2. (1273 aa)
GIPC2PDZ domain-containing protein GIPC2. (311 aa)
NETO1Neuropilin and tolloid-like protein 1 isoform X1. (532 aa)
RAB3ARas-related protein Rab-3A. (220 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
KCNJ10ATP-sensitive inward rectifier potassium channel 10. (379 aa)
EPHB2Ephrin type-B receptor 2 isoform X1. (964 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (820 aa)
LRRTM2Leucine-rich repeat transmembrane neuronal protein 2 isoform X1. (516 aa)
SERPINE2Glia-derived nexin isoform X2; Belongs to the serpin family. (398 aa)
GRM5Metabotropic glutamate receptor 5 isoform X1. (1204 aa)
LOC103078014Protein unc-13 homolog C-like. (782 aa)
PRRT1Proline-rich transmembrane protein 1. (305 aa)
NPAS4Neuronal PAS domain-containing protein 4. (798 aa)
NCSTNNicastrin isoform X1. (709 aa)
SYNGAP1ras/Rap GTPase-activating protein SynGAP. (1324 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (461 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (535 aa)
PAIP2LOW QUALITY PROTEIN: polyadenylate-binding protein-interacting protein 2. (127 aa)
CALB2Calretinin isoform X1. (272 aa)
UNC13CProtein unc-13 homolog C. (1426 aa)
RGS14Regulator of G-protein signaling 14. (567 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
GRIN2DGlutamate receptor ionotropic, NMDA 2D. (1334 aa)
DBN1Drebrin. (648 aa)
LOC10308425314-3-3 protein gamma-like; Belongs to the 14-3-3 family. (245 aa)
SLC4A10Anion exchange protein. (1116 aa)
BAI1Brain-specific angiogenesis inhibitor 1; Belongs to the G-protein coupled receptor 2 family. (1559 aa)
NRGNNeurogranin. (78 aa)
SHISA9Protein shisa-9. (425 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (858 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
IGSF11LOW QUALITY PROTEIN: immunoglobulin superfamily member 11. (431 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
JPH4Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (628 aa)
KAT2AHistone acetyltransferase KAT2A isoform X1. (838 aa)
SLC24A1Sodium/potassium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1066 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
GRID2IPDelphilin. (1214 aa)
GRID2Glutamate receptor ionotropic, delta-2 isoform X1. (1007 aa)
SYPSynaptophysin. (313 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
ERC2ERC protein 2. (854 aa)
NF1Neurofibromin isoform X1. (2841 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
SYT12Synaptotagmin-12 isoform X1. (421 aa)
TNRtenascin-R. (1358 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
RASGRF2Ras-specific guanine nucleotide-releasing factor 2. (1239 aa)
PICK1PRKCA-binding protein isoform X1. (417 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (350 aa)
NCDNNeurochondrin isoform X1. (729 aa)
S100BProtein S100; Belongs to the S-100 family. (92 aa)
ZZEF1Zinc finger ZZ-type and EF-hand domain-containing protein 1. (2937 aa)
PRRT2LOW QUALITY PROTEIN: proline-rich transmembrane protein 2. (411 aa)
DRD2D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1496 aa)
PLK2Serine/threonine-protein kinase PLK. (692 aa)
MPP2MAGUK p55 subfamily member 2 isoform X1; Belongs to the MAGUK family. (569 aa)
SYAP1Synapse-associated protein 1 isoform X1. (358 aa)
CLN3Battenin. (444 aa)
SHISA6Protein shisa-6 homolog isoform X1. (553 aa)
SYNGR1Synaptogyrin. (234 aa)
SHISA8Uncharacterized protein. (347 aa)
GRIN2AGlutamate receptor ionotropic, NMDA 2A. (1464 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
CPLX2Complexin-2. (134 aa)
ARCActivity-regulated cytoskeleton-associated protein. (396 aa)
GRIK2Glutamate receptor ionotropic, kainate 2-like isoform X1. (908 aa)
RIMS2Regulating synaptic membrane exocytosis protein 2 isoform X1. (1557 aa)
LRRTM1Leucine-rich repeat transmembrane neuronal protein 1. (522 aa)
SQSTM1Sequestosome-1. (440 aa)
APPAmyloid beta A4 protein isoform X1. (767 aa)
PTNPleiotrophin isoform X1. (181 aa)
EPHA4Ephrin type-A receptor 4-like isoform X1. (986 aa)
SCTSecretin. (134 aa)
HRASGTPase HRas isoform X1. (189 aa)
LOC103085844Monoacylglycerol lipase abhd6-B-like. (326 aa)
CRHR2Corticotropin-releasing factor receptor 2 isoform X1; Belongs to the G-protein coupled receptor 2 family. (437 aa)
CX3CR1CX3C chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (358 aa)
CHRDL1Chordin-like protein 1 isoform X1. (459 aa)
SHISA7Protein shisa-7. (543 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
DGKIDiacylglycerol kinase. (1078 aa)
RELNReelin isoform X1. (3460 aa)
LOC103069787BDNF/NT-3 growth factors receptor-like isoform X1. (553 aa)
SLC24A2Sodium/potassium/calcium exchanger 2 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (662 aa)
CDC20Cell division cycle protein 20 homolog. (499 aa)
JPH3Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (738 aa)
NEURL1E3 ubiquitin-protein ligase NEURL1. (574 aa)
CDK5Cyclin-dependent kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
ERC1ELKS/Rab6-interacting/CAST family member 1 isoform X1. (1116 aa)
SCGNSecretagogin. (276 aa)
ABHD6Monoacylglycerol lipase ABHD6 isoform X1. (337 aa)
GIPC1PDZ domain-containing protein GIPC1 isoform X1. (333 aa)
LZTS1LOW QUALITY PROTEIN: leucine zipper putative tumor suppressor 1. (621 aa)
CNTN2Contactin-2. (1040 aa)
SORCS3LOW QUALITY PROTEIN: VPS10 domain-containing receptor SorCS3. (1226 aa)
RAB5ARas-related protein Rab-5A isoform X1. (215 aa)
STXBP1Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
VGFLOW QUALITY PROTEIN: VGF nerve growth factor inducible. (604 aa)
YWHAGLOW QUALITY PROTEIN: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma; Belongs to the 14-3-3 family. (247 aa)
LOC103068707Cholesterol 24-hydroxylase-like; Belongs to the cytochrome P450 family. (501 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (397 aa)
GRIN2CGlutamate receptor ionotropic, NMDA 2C. (1201 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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