STRINGSTRING
NF1 NF1 TFAP2B TFAP2B PKD2 PKD2 LRP2 LRP2 KDR KDR PIK3R3 PIK3R3 ACVRL1 ACVRL1 ACKR3 ACKR3 FOXN1 FOXN1 EGR3 EGR3 CDH13 CDH13 C1GALT1 C1GALT1 SGCD SGCD SLIT2 SLIT2 PTK2 PTK2 SMAD7 SMAD7 NDNF NDNF PRDM1 PRDM1 STK4 STK4 TBX4 TBX4 PIK3CA PIK3CA COL3A1 COL3A1 SFRP2 SFRP2 B4GALT1 B4GALT1 HOXA7 HOXA7 FLT4 FLT4 FGF18 FGF18 CITED2 CITED2 NOX1 NOX1 HOXA3 HOXA3 PDCL3 PDCL3 GLMN GLMN CALD1 CALD1 TIE1 TIE1 EIF2AK3 EIF2AK3 FBXW7 FBXW7 FGF1 FGF1 JUNB JUNB ITGA5 ITGA5 BMPR2 BMPR2 TNNI3 TNNI3 NR2F2 NR2F2 PKNOX1 PKNOX1 NPRL3 NPRL3 ADAM8 ADAM8 OTULIN OTULIN COL18A1 COL18A1 NOV NOV LEF1 LEF1 TCF21 TCF21 SGPL1 SGPL1 LOC103090748 LOC103090748 NR4A1 NR4A1 MYOCD MYOCD ITGA2B ITGA2B PLCD3 PLCD3 TGFA TGFA PRKCA PRKCA HAND1 HAND1 COL4A1 COL4A1 CDH2 CDH2 GDF2 GDF2 APLNR APLNR ELK3 ELK3 JMJD6 JMJD6 PDGFRA PDGFRA NTRK2 NTRK2 ZC3H12A ZC3H12A RECK RECK CCDC134 CCDC134 PANK2 PANK2 SERPINF2 SERPINF2 THY1 THY1 CTGF CTGF MCAM MCAM PPP3R2 PPP3R2 HAND2 HAND2 GNA13 GNA13 ZFP36L1 ZFP36L1 ITGB1BP1 ITGB1BP1 ITGB8 ITGB8 ROBO1 ROBO1 LOC103069787 LOC103069787 LOC103080655 LOC103080655 FOXF1 FOXF1 ATP5B ATP5B ADIPOR2 ADIPOR2 EPHB4 EPHB4 LOC103073179 LOC103073179 SRPX2 SRPX2 ADRA2B ADRA2B LEP LEP FBXW9 FBXW9 PXDN PXDN GPR56 GPR56 FGF2 FGF2 CTNNB1 CTNNB1 ANGPT2 ANGPT2 APOLD1 APOLD1 EPHB3 EPHB3 NRP2 NRP2 SETD2 SETD2 ESM1 ESM1 FGF8 FGF8 SMO SMO EDNRA EDNRA NRP1 NRP1 ANPEP ANPEP CHD7 CHD7 SIX1 SIX1 MFGE8 MFGE8 CALCRL CALCRL CIB1 CIB1 HIF1A HIF1A PARVA PARVA VHL VHL ETV2 ETV2 ENG ENG ITGB1 ITGB1 FLT1 FLT1 ITGAV ITGAV CLEC14A CLEC14A CAV1 CAV1 GPLD1 GPLD1 EDN2 EDN2 HAS2 HAS2 T T BMP4 BMP4 PDCD10 PDCD10 LOC103083349 LOC103083349 PRCP PRCP SYK SYK UBP1 UBP1 MYH9 MYH9 IHH IHH NFATC4 NFATC4 DLL1 DLL1 RSPO3 RSPO3 KLF5 KLF5 SOS1 SOS1 LOC103091514 LOC103091514 GPR124 GPR124 EDN1 EDN1 TBX20 TBX20 BMPER BMPER ANGPT1 ANGPT1 PROK2 PROK2 VSTM4 VSTM4 FZD4 FZD4 HEY2 HEY2 POFUT1 POFUT1 ZFPM2 ZFPM2 STRA6 STRA6 EFNB2 EFNB2 FOXH1 FOXH1 AMOT AMOT ANGPT4 ANGPT4 ZMIZ1 ZMIZ1 PTK2B PTK2B FIGF FIGF PLXDC1 PLXDC1 HOXA13 HOXA13 SAT1 SAT1 MEOX2 MEOX2 COL22A1 COL22A1 PTPRB PTPRB FGF9 FGF9 ANGPTL3 ANGPTL3 EMC10 EMC10 AMOTL1 AMOTL1 TEAD2 TEAD2 MED1 MED1 LOC103076742 LOC103076742 EGF EGF HOXB13 HOXB13 TAL1 TAL1 NOG NOG HDAC7 HDAC7 TBX2 TBX2 EMCN EMCN APOB APOB IL18 IL18 FAP FAP EPGN EPGN MEIS1 MEIS1 PPP3R1 PPP3R1 SOX17 SOX17 GBX2 GBX2 VEZF1 VEZF1 KRIT1 KRIT1 ARID2 ARID2 ECSCR ECSCR TGFBI TGFBI FZD5 FZD5 ROBO4 ROBO4 COMP COMP RASIP1 RASIP1 HS6ST1 HS6ST1 VEGFB VEGFB LOC103081344 LOC103081344 LOC103069848 LOC103069848 TMEM100 TMEM100 COL15A1 COL15A1 PRKX PRKX LOC103075090 LOC103075090 PLXND1 PLXND1 LDLR LDLR ANGPTL4 ANGPTL4 JUN JUN GREM1 GREM1 MYO18B MYO18B ACTG1 ACTG1 DLL4 DLL4 VASH1 VASH1 PGF PGF FGF10 FGF10 WNT11 WNT11 TGFBR1 TGFBR1 EPHA2 EPHA2 CXCR3 CXCR3 GJA5 GJA5 SPRED1 SPRED1 THBS1 THBS1 SCG2 SCG2 LEPR LEPR NOTCH1 NOTCH1 EPHB2 EPHB2 WASF2 WASF2 MYO1E MYO1E TGFB1 TGFB1 MMP2 MMP2 EYA1 EYA1 CXCL17 CXCL17 ANGPTL6 ANGPTL6 TSPAN12 TSPAN12 MMRN2 MMRN2 VEGFA VEGFA NRARP NRARP RORA RORA TIPARP TIPARP LOC103088826 LOC103088826 EPAS1 EPAS1 GPR15 GPR15 AMOTL2 AMOTL2 FLNA FLNA PAXIP1 PAXIP1 LOC103079308 LOC103079308 CYR61 CYR61 PRRX1 PRRX1 EFNA1 EFNA1 SEMA4A SEMA4A CLIC4 CLIC4 HES1 HES1 SIRT1 SIRT1 FN1 FN1 HPGD HPGD LOXL2 LOXL2 WARS2 WARS2 SRF SRF BMPR1A BMPR1A CUL7 CUL7 SHC1 SHC1 APOA1BP APOA1BP EPHB1 EPHB1 SEMA3E SEMA3E NRCAM NRCAM GJC1 GJC1 E2F8 E2F8 SHB SHB TEK TEK NOTCH2 NOTCH2 SHH SHH NR2E1 NR2E1 PLXDC2 PLXDC2 LOC103069050 LOC103069050 YAP1 YAP1 CCM2 CCM2 LOC103087231 LOC103087231 LOC103083261 LOC103083261 FKBP10 FKBP10 LOX LOX HPSE HPSE RASA1 RASA1 PROK1 PROK1 SATL1 SATL1 LRP5 LRP5 LOC103072909 LOC103072909 PDGFRB PDGFRB VEGFC VEGFC E2F7 E2F7 PROX1 PROX1 RBM15 RBM15 GPR116 GPR116 S1PR1 S1PR1 JAG1 JAG1 AAMP AAMP SEC24B SEC24B JAM3 JAM3 HEY1 HEY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NF1Neurofibromin isoform X1. (2841 aa)
TFAP2BTranscription factor AP-2-beta isoform X1. (469 aa)
PKD2LOW QUALITY PROTEIN: polycystin-2. (963 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4672 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
FOXN1Forkhead box protein N1. (645 aa)
EGR3Early growth response protein 3 isoform X1. (387 aa)
CDH13Cadherin-13 isoform X1. (713 aa)
C1GALT1glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1. (376 aa)
SGCDDelta-sarcoglycan-like. (289 aa)
SLIT2LOW QUALITY PROTEIN: slit homolog 2 protein. (1521 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1003 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
NDNFProtein NDNF. (568 aa)
PRDM1PR domain zinc finger protein 1 isoform X1. (826 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
TBX4T-box transcription factor TBX4. (555 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
COL3A1Collagen alpha-1(III) chain-like. (1462 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
B4GALT1Beta-1,4-galactosyltransferase 1 isoform X1. (404 aa)
HOXA7Homeobox protein Hox-A7. (233 aa)
FLT4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1594 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
CITED2Cbp/p300-interacting transactivator 2 isoform X1. (272 aa)
NOX1LOW QUALITY PROTEIN: NADPH oxidase 1. (562 aa)
HOXA3Homeobox protein Hox-A3. (385 aa)
PDCL3Phosducin-like protein 3. (129 aa)
GLMNGlomulin isoform X1. (592 aa)
CALD1Non-muscle caldesmon isoform X1. (554 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
EIF2AK3Eukaryotic translation initiation factor 2-alpha kinase 3 isoform X1. (1118 aa)
FBXW7F-box/WD repeat-containing protein 7 isoform X1. (707 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa)
JUNBTranscription factor jun-B. (347 aa)
ITGA5Integrin alpha-5; Belongs to the integrin alpha chain family. (1053 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
TNNI3Troponin I, cardiac muscle. (211 aa)
NR2F2COUP transcription factor 2-like isoform X1. (414 aa)
PKNOX1Homeobox protein PKNOX1 isoform X1. (436 aa)
NPRL3Nitrogen permease regulator 3-like protein isoform X2. (582 aa)
ADAM8Disintegrin and metalloproteinase domain-containing protein 8. (1009 aa)
OTULINUbiquitin thioesterase otulin. (352 aa)
COL18A1Collagen alpha-1(XVIII) chain. (1513 aa)
NOVProtein NOV homolog isoform X1. (358 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
TCF21LOW QUALITY PROTEIN: transcription factor 21. (179 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
LOC103090748Zinc finger protein 36, C3H1 type-like 1-like. (226 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1 isoform X1. (598 aa)
MYOCDMyocardin isoform X1. (984 aa)
ITGA2BIntegrin alpha-IIb; Belongs to the integrin alpha chain family. (1035 aa)
PLCD3Phosphoinositide phospholipase C. (786 aa)
TGFAProtransforming growth factor alpha. (145 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
COL4A1Collagen alpha-1(IV) chain. (1668 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
GDF2Growth/differentiation factor 2. (431 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
ELK3ETS domain-containing protein Elk-3. (403 aa)
JMJD6Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X1. (414 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
NTRK2Tyrosine-protein kinase receptor. (366 aa)
ZC3H12ARibonuclease ZC3H12A. (583 aa)
RECKReversion-inducing cysteine-rich protein with Kazal motifs. (971 aa)
CCDC134Coiled-coil domain-containing protein 134. (229 aa)
PANK2Pantothenate kinase 2, mitochondrial. (449 aa)
SERPINF2Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (494 aa)
THY1Thy-1 membrane glycoprotein. (161 aa)
CTGFConnective tissue growth factor. (349 aa)
MCAMCell surface glycoprotein MUC18. (670 aa)
PPP3R2LOW QUALITY PROTEIN: calcineurin subunit B type 2. (170 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (165 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (377 aa)
ZFP36L1Zinc finger protein 36, C3H1 type-like 1-like. (338 aa)
ITGB1BP1Integrin beta-1-binding protein 1 isoform X1. (200 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
ROBO1Roundabout homolog 1-like isoform X1. (1652 aa)
LOC103069787BDNF/NT-3 growth factors receptor-like isoform X1. (553 aa)
LOC103080655chromodomain-helicase-DNA-binding protein 7-like. (414 aa)
FOXF1Forkhead box protein F1. (377 aa)
ATP5BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (528 aa)
ADIPOR2Adiponectin receptor protein 2. (386 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
LOC103073179Phosducin-like protein 3-like. (122 aa)
SRPX2Sushi repeat-containing protein SRPX2. (465 aa)
ADRA2Balpha-2B adrenergic receptor. (440 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
FBXW9F-box/WD repeat-containing protein 9. (458 aa)
PXDNPeroxidasin homolog. (1295 aa)
GPR56G-protein coupled receptor 56 isoform X1; Belongs to the G-protein coupled receptor 2 family. (692 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
ANGPT2Angiopoietin-2. (496 aa)
APOLD1Apolipoprotein L domain-containing protein 1. (248 aa)
EPHB3Ephrin type-B receptor 3. (1005 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
SETD2Histone-lysine N-methyltransferase SETD2. (2562 aa)
ESM1Endothelial cell-specific molecule 1 isoform X1. (184 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
EDNRAEndothelin-1 receptor isoform X2. (318 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
ANPEPAminopeptidase. (965 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2305 aa)
SIX1Homeobox protein SIX1. (284 aa)
MFGE8Lactadherin isoform X1. (431 aa)
CALCRLCalcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (462 aa)
CIB1Calcium and integrin-binding protein 1. (191 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X2. (822 aa)
PARVAAlpha-parvin. (412 aa)
VHLLOW QUALITY PROTEIN: von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase. (219 aa)
ETV2LOW QUALITY PROTEIN: ETS translocation variant 2. (333 aa)
ENGEndoglin. (661 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (805 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (1311 aa)
CLEC14ALOW QUALITY PROTEIN: C-type lectin domain family 14, member A. (497 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D isoform X1. (839 aa)
EDN2Endothelin-2. (180 aa)
HAS2Hyaluronan synthase 2-like. (552 aa)
TBrachyury protein isoform X1. (435 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
PDCD10Programmed cell death protein 10 isoform X1. (212 aa)
LOC103083349Cytochrome P450 1B1-like; Belongs to the cytochrome P450 family. (543 aa)
PRCPLysosomal Pro-X carboxypeptidase. (497 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
UBP1Upstream-binding protein 1 isoform X1. (537 aa)
MYH9Myosin-9 isoform X2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1963 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
NFATC4Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (901 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (721 aa)
RSPO3R-spondin-3. (275 aa)
KLF5Krueppel-like factor 5 isoform X1. (454 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
LOC103091514Phosducin-like protein 3-like. (237 aa)
GPR124G-protein coupled receptor 124; Belongs to the G-protein coupled receptor 2 family. (1276 aa)
EDN1Endothelin-1. (202 aa)
TBX20T-box transcription factor TBX20. (449 aa)
BMPERBMP-binding endothelial regulator protein isoform X1. (685 aa)
ANGPT1Angiopoietin-1 isoform X1. (498 aa)
PROK2Prokineticin-2 isoform X1. (130 aa)
VSTM4V-set and transmembrane domain-containing protein 4. (317 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (352 aa)
POFUT1GDP-fucose protein O-fucosyltransferase 1 isoform X1. (391 aa)
ZFPM2Zinc finger protein ZFPM2 isoform X1. (1151 aa)
STRA6Stimulated by retinoic acid gene 6 protein homolog isoform X2. (675 aa)
EFNB2ephrin-B2; Belongs to the ephrin family. (333 aa)
FOXH1Forkhead box protein H1. (360 aa)
AMOTAngiomotin. (1085 aa)
ANGPT4Angiopoietin-4. (498 aa)
ZMIZ1Zinc finger MIZ domain-containing protein 1. (1065 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
FIGFVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
PLXDC1Plexin domain-containing protein 1. (501 aa)
HOXA13Homeobox protein Hox-A13. (297 aa)
SAT1Diamine acetyltransferase 1. (171 aa)
MEOX2Homeobox protein MOX-2. (303 aa)
COL22A1Collagen alpha-1(XXII) chain. (1599 aa)
PTPRBReceptor-type tyrosine-protein phosphatase beta isoform X1. (2213 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ANGPTL3Angiopoietin-related protein 3. (463 aa)
EMC10ER membrane protein complex subunit 10 isoform X1. (260 aa)
AMOTL1Angiomotin-like protein 1. (896 aa)
TEAD2Transcriptional enhancer factor TEF-4 isoform X1. (451 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
LOC103076742Protein transport protein Sec24B-like. (242 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
HOXB13Homeobox protein Hox-B13. (285 aa)
TAL1T-cell acute lymphocytic leukemia protein 1. (318 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (946 aa)
TBX2T-box transcription factor TBX2. (875 aa)
EMCNEndomucin. (262 aa)
APOBLOW QUALITY PROTEIN: apolipoprotein B-100. (4572 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
FAPSeprase isoform X1; Belongs to the peptidase S9B family. (760 aa)
EPGNEpigen isoform X1. (153 aa)
MEIS1Homeobox protein Meis2 isoform X1. (475 aa)
PPP3R1Calcineurin subunit B type 1. (160 aa)
SOX17Transcription factor SOX-17. (405 aa)
GBX2Homeobox protein GBX-2. (348 aa)
VEZF1Vascular endothelial zinc finger 1. (511 aa)
KRIT1Krev interaction trapped protein 1 isoform X1. (736 aa)
ARID2AT-rich interactive domain-containing protein 2. (1835 aa)
ECSCREndothelial cell-specific chemotaxis regulator. (241 aa)
TGFBITransforming growth factor-beta-induced protein ig-h3. (683 aa)
FZD5Frizzled-5; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa)
ROBO4Roundabout homolog 4. (1005 aa)
COMPCartilage oligomeric matrix protein isoform X1. (756 aa)
RASIP1Ras-interacting protein 1. (962 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (411 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
LOC103081344Folate receptor alpha-like. (251 aa)
LOC103069848Putative Bcl-2 homologous antagonist/killer 2-like. (211 aa)
TMEM100Transmembrane protein 100. (134 aa)
COL15A1Collagen alpha-1(XV) chain. (1366 aa)
PRKXcAMP-dependent protein kinase catalytic subunit PRKX; Belongs to the protein kinase superfamily. (358 aa)
LOC103075090UPF0556 protein C19orf10 homolog. (167 aa)
PLXND1plexin-D1. (1747 aa)
LDLRLow-density lipoprotein receptor. (857 aa)
ANGPTL4Angiopoietin-related protein 4 isoform X1. (412 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (337 aa)
GREM1Gremlin. (184 aa)
MYO18BUnconventional myosin-XVIIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2526 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
VASH1Vasohibin-1. (363 aa)
PGFPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
CXCR3c-X-C chemokine receptor type 3; Belongs to the G-protein coupled receptor 1 family. (366 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
SPRED1Sprouty-related, EVH1 domain-containing protein 1. (443 aa)
THBS1Thrombospondin-1. (1170 aa)
SCG2Secretogranin-2. (616 aa)
LEPRLeptin receptor isoform X1. (1165 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2536 aa)
EPHB2Ephrin type-B receptor 2 isoform X1. (964 aa)
WASF2wiskott-Aldrich syndrome protein family member 2 isoform X1. (498 aa)
MYO1EUnconventional myosin-Ie isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
MMP272 kDa type IV collagenase. (584 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (594 aa)
CXCL17VEGF coregulated chemokine 1. (119 aa)
ANGPTL6Angiopoietin-related protein 6 isoform X2. (473 aa)
TSPAN12Tetraspanin. (305 aa)
MMRN2Multimerin-2. (935 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
RORALOW QUALITY PROTEIN: nuclear receptor ROR-alpha. (527 aa)
TIPARPTCDD-inducible poly [ADP-ribose] polymerase isoform X1. (658 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
EPAS1Endothelial PAS domain-containing protein 1. (869 aa)
GPR15G-protein coupled receptor 15; Belongs to the G-protein coupled receptor 1 family. (358 aa)
AMOTL2Angiomotin-like protein 2 isoform X1. (776 aa)
FLNAfilamin-A isoform X1. (2647 aa)
PAXIP1PAX-interacting protein 1. (964 aa)
LOC103079308Uncharacterized protein LOC103079308. (289 aa)
CYR61Protein CYR61. (382 aa)
PRRX1Paired mesoderm homeobox protein 1 isoform X1. (245 aa)
EFNA1ephrin-A1; Belongs to the ephrin family. (242 aa)
SEMA4Asemaphorin-4A; Belongs to the semaphorin family. (762 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
HES1Transcription factor HES-1. (280 aa)
SIRT1LOW QUALITY PROTEIN: NAD-dependent protein deacetylase sirtuin-1. (695 aa)
FN1LOW QUALITY PROTEIN: fibronectin. (2483 aa)
HPGD15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
LOXL2Lysyl oxidase homolog 2 isoform X1. (774 aa)
WARS2tryptophan--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (389 aa)
SRFSerum response factor. (510 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
CUL7Cullin-7 isoform X1; Belongs to the cullin family. (1726 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
APOA1BPNAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
EPHB1Ephrin type-B receptor 1. (984 aa)
SEMA3Esemaphorin-3E-like; Belongs to the semaphorin family. (715 aa)
NRCAMNeuronal cell adhesion molecule isoform X1. (1212 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
E2F8LOW QUALITY PROTEIN: transcription factor E2F8. (869 aa)
SHBLOW QUALITY PROTEIN: SH2 domain-containing adapter protein B. (595 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
NOTCH2Neurogenic locus notch homolog protein 2-like. (2471 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
PLXDC2Plexin domain-containing protein 2 isoform X1. (530 aa)
LOC103069050Glutamine synthetase. (381 aa)
YAP1Yorkie homolog. (430 aa)
CCM2Malcavernin. (476 aa)
LOC103087231Yorkie homolog isoform X1. (489 aa)
LOC103083261Protein HEG homolog 1-like. (1196 aa)
FKBP10Peptidylprolyl isomerase. (583 aa)
LOXProtein-lysine 6-oxidase isoform X1. (413 aa)
HPSEHeparanase isoform X1. (542 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
PROK1LOW QUALITY PROTEIN: prokineticin-1. (130 aa)
SATL1Spermidine/spermine N(1)-acetyltransferase-like protein 1. (169 aa)
LRP5Low-density lipoprotein receptor-related protein 5. (1451 aa)
LOC103072909Protein HEG homolog 1-like. (136 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
E2F7Transcription factor E2F7. (905 aa)
PROX1Prospero homeobox protein 1. (737 aa)
RBM15Putative RNA-binding protein 15 isoform X1. (1005 aa)
GPR116Probable G-protein coupled receptor 116; Belongs to the G-protein coupled receptor 2 family. (1342 aa)
S1PR1Sphingosine 1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
AAMPAngio-associated migratory cell protein. (434 aa)
SEC24BProtein transport protein Sec24B-like. (919 aa)
JAM3Junctional adhesion molecule C. (383 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1. (308 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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