76 items (Lipotes vexillifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDKL3	LOW QUALITY PROTEIN: cyclin-dependent kinase-like 3. (584 aa)
	BMP4	Bone morphogenetic protein 4 isoform X1. (420 aa)
	SEMA7A	semaphorin-7A isoform X1; Belongs to the semaphorin family. (663 aa)
	WWC1	Protein KIBRA. (1110 aa)
	SEMA4D	semaphorin-4D; Belongs to the semaphorin family. (863 aa)
	ADRB2	Beta-2 adrenergic receptor. (419 aa)
	LOC103083351	LOW QUALITY PROTEIN: semaphorin-6D-like; Belongs to the semaphorin family. (1131 aa)
	SAV1	Protein salvador homolog 1. (384 aa)
	SEMA5B	semaphorin-5B isoform X1. (1093 aa)
	TP73	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (638 aa)
	LOC103085370	Placenta-specific gene 8 protein-like. (113 aa)
	ADRB3	LOW QUALITY PROTEIN: beta-3 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family. (375 aa)
	PTCH1	Protein patched homolog 1 isoform X1. (1448 aa)
	RAI1	Retinoic acid-induced protein 1. (2042 aa)
	SEMA6A	semaphorin-6A isoform X1; Belongs to the semaphorin family. (1044 aa)
	LOC103085385	Neuroendocrine secretory protein 55-like. (242 aa)
	IFRD2	Interferon-related developmental regulator 2. (441 aa)
	TNR	tenascin-R. (1358 aa)
	DIP2B	Disco-interacting protein 2 homolog B. (1576 aa)
	MAPK11	Mitogen-activated protein kinase. (350 aa)
	SLC6A4	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
	SEMA3G	semaphorin-3G; Belongs to the semaphorin family. (772 aa)
	KIAA0319	Dyslexia-associated protein KIAA0319 homolog isoform X2. (1083 aa)
	TLL2	Metalloendopeptidase. (1020 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	LGMN	Legumain. (434 aa)
	SEMA3E	semaphorin-3E-like; Belongs to the semaphorin family. (715 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	RYK	Tyrosine-protein kinase RYK. (475 aa)
	SEMA4A	semaphorin-4A; Belongs to the semaphorin family. (762 aa)
	STK3	Serine/threonine-protein kinase 3 isoform X1. (491 aa)
	PLXNA3	plexin-A3. (1873 aa)
	SEMA6C	semaphorin-6C isoform X1; Belongs to the semaphorin family. (966 aa)
	NTN1	Netrin-1 isoform X1. (604 aa)
	GSK3A	Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
	SEMA6B	semaphorin-6B; Belongs to the semaphorin family. (812 aa)
	SEMA4F	semaphorin-4F; Belongs to the semaphorin family. (777 aa)
	NKD1	Protein naked cuticle homolog 1. (471 aa)
	BBS2	Bardet-Biedl syndrome 2 protein homolog. (721 aa)
	RTN4R	Reticulon-4 receptor. (831 aa)
	GDF15	Growth/differentiation factor 15. (308 aa)
	JARID2	LOW QUALITY PROTEIN: protein Jumonji. (1237 aa)
	PTPRS	Receptor-type tyrosine-protein phosphatase S isoform X2. (1948 aa)
	DRAXIN	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (349 aa)
	WWC3	Protein WWC3. (1097 aa)
	FSTL4	Follistatin-related protein 4. (844 aa)
	SEMA5A	semaphorin-5A. (1073 aa)
	SEMA3D	semaphorin-3D; Belongs to the semaphorin family. (777 aa)
	SPG20	Spartin isoform X1. (668 aa)
	EPHA7	Ephrin type-A receptor 7-like isoform X1. (998 aa)
	SEMA3A	semaphorin-3A; Belongs to the semaphorin family. (772 aa)
	ULK1	Serine/threonine-protein kinase ULK1. (1055 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
	DUSP10	Dual specificity protein phosphatase 10 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (483 aa)
	STK4	Serine/threonine-protein kinase 4. (487 aa)
	SEMA3C	semaphorin-3C; Belongs to the semaphorin family. (751 aa)
	FXN	Frataxin, mitochondrial. (215 aa)
	MSTN	Growth/differentiation factor 8. (366 aa)
	SEMA3B	semaphorin-3B isoform X3; Belongs to the semaphorin family. (753 aa)
	WNT3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	PI16	Peptidase inhibitor 16 isoform X1; Belongs to the CRISP family. (460 aa)
	RTN4	Reticulon. (1187 aa)
	WWC2	Protein WWC2. (1193 aa)
	SEMA3F	semaphorin-3F isoform X1; Belongs to the semaphorin family. (785 aa)
	CDKN1A	Cyclin-dependent kinase inhibitor 1 isoform X1. (164 aa)
	MYOZ1	Myozenin-1. (298 aa)
	SOCS2	Suppressor of cytokine signaling 2 isoform X1. (198 aa)
	OSTN	Osteocrin. (132 aa)
	TBX5	T-box transcription factor TBX5 isoform X1. (519 aa)
	ADRB1	Beta-1 adrenergic receptor. (465 aa)
	CDK5	Cyclin-dependent kinase 5 isoform X1; Belongs to the protein kinase superfamily. (292 aa)
	CDKN1B	Cyclin-dependent kinase inhibitor 1B. (198 aa)
	LOC103072643	Frataxin, mitochondrial-like. (197 aa)
	SEMA4B	semaphorin-4B; Belongs to the semaphorin family. (822 aa)
	SEMA4C	semaphorin-4C; Belongs to the semaphorin family. (833 aa)
	SEMA4G	semaphorin-4G; Belongs to the semaphorin family. (843 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRB1	ADRB2	A0A340Y980	A0A340WFY6	Beta-1 adrenergic receptor.	Beta-2 adrenergic receptor.	0.986
ADRB1	ADRB3	A0A340Y980	A0A340WL74	Beta-1 adrenergic receptor.	LOW QUALITY PROTEIN: beta-3 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family.	0.983
ADRB1	LOC103085385	A0A340Y980	A0A340WRC9	Beta-1 adrenergic receptor.	Neuroendocrine secretory protein 55-like.	0.901
ADRB2	ADRB1	A0A340WFY6	A0A340Y980	Beta-2 adrenergic receptor.	Beta-1 adrenergic receptor.	0.986
ADRB2	ADRB3	A0A340WFY6	A0A340WL74	Beta-2 adrenergic receptor.	LOW QUALITY PROTEIN: beta-3 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family.	0.983
ADRB2	LOC103085385	A0A340WFY6	A0A340WRC9	Beta-2 adrenergic receptor.	Neuroendocrine secretory protein 55-like.	0.901
ADRB3	ADRB1	A0A340WL74	A0A340Y980	LOW QUALITY PROTEIN: beta-3 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family.	Beta-1 adrenergic receptor.	0.983
ADRB3	ADRB2	A0A340WL74	A0A340WFY6	LOW QUALITY PROTEIN: beta-3 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family.	Beta-2 adrenergic receptor.	0.983
ADRB3	LOC103085385	A0A340WL74	A0A340WRC9	LOW QUALITY PROTEIN: beta-3 adrenergic receptor; Belongs to the G-protein coupled receptor 1 family.	Neuroendocrine secretory protein 55-like.	0.901
BMP4	NOG	A0A340W9C9	A0A340XUU4	Bone morphogenetic protein 4 isoform X1.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.995
BMP4	PTCH1	A0A340W9C9	A0A340WMN5	Bone morphogenetic protein 4 isoform X1.	Protein patched homolog 1 isoform X1.	0.518
BMP4	TBX5	A0A340W9C9	A0A340Y885	Bone morphogenetic protein 4 isoform X1.	T-box transcription factor TBX5 isoform X1.	0.517
BMP4	WNT3	A0A340W9C9	A0A340Y1H8	Bone morphogenetic protein 4 isoform X1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.639
BMP4	WNT3A	A0A340W9C9	A0A340X5F1	Bone morphogenetic protein 4 isoform X1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.639
BMP4	WNT5A	A0A340W9C9	A0A340XA82	Bone morphogenetic protein 4 isoform X1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.539
CDK5	CDKN1A	A0A340Y9Y7	A0A340Y751	Cyclin-dependent kinase 5 isoform X1; Belongs to the protein kinase superfamily.	Cyclin-dependent kinase inhibitor 1 isoform X1.	0.537
CDK5	CDKN1B	A0A340Y9Y7	A0A340YD89	Cyclin-dependent kinase 5 isoform X1; Belongs to the protein kinase superfamily.	Cyclin-dependent kinase inhibitor 1B.	0.521
CDK5	GSK3A	A0A340Y9Y7	A0A340XHB3	Cyclin-dependent kinase 5 isoform X1; Belongs to the protein kinase superfamily.	Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily.	0.497
CDK5	PLXNA3	A0A340Y9Y7	A0A340XE65	Cyclin-dependent kinase 5 isoform X1; Belongs to the protein kinase superfamily.	plexin-A3.	0.571
CDK5	SEMA3A	A0A340Y9Y7	A0A340XUH2	Cyclin-dependent kinase 5 isoform X1; Belongs to the protein kinase superfamily.	semaphorin-3A; Belongs to the semaphorin family.	0.689