STRINGSTRING
USF2 USF2 BMP4 BMP4 PAX8 PAX8 WNT10A WNT10A SULF2 SULF2 ATM ATM ARF6 ARF6 LOC103070587 LOC103070587 AR AR LOC103087942 LOC103087942 FEM1B FEM1B SRC SRC LOC103068298 LOC103068298 STAT5B STAT5B EDN1 EDN1 MST1 MST1 ALDH1A3 ALDH1A3 ORAI1 ORAI1 MSN MSN CEBPB CEBPB LOC103082450 LOC103082450 SMAD3 SMAD3 RXFP1 RXFP1 STRA6 STRA6 PML PML STAT5A STAT5A LOC103087126 LOC103087126 BMP7 BMP7 ASXL1 ASXL1 SEC63 SEC63 ACADM ACADM ZNF330 ZNF330 IL6 IL6 CSF1 CSF1 TGM2 TGM2 GHRH GHRH COBL COBL PCK2 PCK2 LRP5 LRP5 EAF2 EAF2 LOC103082172 LOC103082172 ARID5B ARID5B MAP2K1 MAP2K1 HNF1A HNF1A PTCH1 PTCH1 RARG RARG ZNF703 ZNF703 MAPK1 MAPK1 SMARCB1 SMARCB1 GATA6 GATA6 LOC103085851 LOC103085851 WDR77 WDR77 DDX55 DDX55 MKI67 MKI67 E2F7 E2F7 PROX1 PROX1 SLC46A2 SLC46A2 CRKL CRKL DDR1 DDR1 HOXD9 HOXD9 IRS2 IRS2 PCK1 PCK1 CSN3 CSN3 NR5A1 NR5A1 TNC TNC NF1 NF1 HESX1 HESX1 PKD2 PKD2 CUL3 CUL3 CSN2 CSN2 ZIC3 ZIC3 FOXN1 FOXN1 ATF2 ATF2 HOXD3 HOXD3 DNAAF1 DNAAF1 UPF2 UPF2 ELK1 ELK1 WNT2 WNT2 CAV1 CAV1 IRF6 IRF6 ABL1 ABL1 HOXD13 HOXD13 GFER GFER NPHP3 NPHP3 ZMPSTE24 ZMPSTE24 EXT1 EXT1 AIRE AIRE ASCL1 ASCL1 SOX10 SOX10 SOX9 SOX9 MAPK3 MAPK3 DRD2 DRD2 LEF1 LEF1 TCF21 TCF21 IGSF3 IGSF3 ATP2C2 ATP2C2 TGFA TGFA ARMC5 ARMC5 FGF7 FGF7 ONECUT2 ONECUT2 AGPAT6 AGPAT6 FRZB FRZB SERPINF1 SERPINF1 PKD1 PKD1 PDGFRA PDGFRA PAX1 PAX1 CSMD2 CSMD2 HAND2 HAND2 WNT3A WNT3A EDAR EDAR SLC9A3R1 SLC9A3R1 ANXA1 ANXA1 POLB POLB NODAL NODAL PTCD2 PTCD2 SHH SHH LOC103088284 LOC103088284 NOTCH2 NOTCH2 LOC103070918 LOC103070918 E2F8 E2F8 ELF3 ELF3 CTC1 CTC1 SFRP1 SFRP1 ASH1L ASH1L PYGO2 PYGO2 BCL11B BCL11B LOC103085888 LOC103085888 NRG3 NRG3 BMPR1A BMPR1A NR0B1 NR0B1 CCL11 CCL11 SRF SRF WNT5A WNT5A UBE3A UBE3A TWSG1 TWSG1 ARHGAP35 ARHGAP35 KDM5B KDM5B TFCP2L1 TFCP2L1 NKX3-1 NKX3-1 ESR1 ESR1 LATS1 LATS1 LOC103090152 LOC103090152 HES1 HES1 ZBTB7B ZBTB7B ID2 ID2 BSX BSX LOC103079308 LOC103079308 TGFB3 TGFB3 LOC103088556 LOC103088556 TNFRSF11A TNFRSF11A LOC103088826 LOC103088826 IQGAP3 IQGAP3 FOXB1 FOXB1 NTN1 NTN1 LOC103075733 LOC103075733 TP63 TP63 LRRC1 LRRC1 SALL1 SALL1 WT1 WT1 PAX6 PAX6 TPH1 TPH1 LOC103081416 LOC103081416 TGFB1 TGFB1 PSEN1 PSEN1 LHX3 LHX3 NOTCH1 NOTCH1 SERPINE2 SERPINE2 RPGRIP1L RPGRIP1L NOTCH4 NOTCH4 FOXE1 FOXE1 EPHA2 EPHA2 TGFBR1 TGFBR1 WNT11 WNT11 FGF10 FGF10 APOA1 APOA1 ACER1 ACER1 ONECUT1 ONECUT1 TAF10 TAF10 RELA RELA PRKCSH PRKCSH ZBTB1 ZBTB1 FGL1 FGL1 RHBDD3 RHBDD3 JARID2 JARID2 JUN JUN PITX1 PITX1 STK11 STK11 PLXND1 PLXND1 LOC103078858 LOC103078858 ESRP2 ESRP2 AREG AREG RAF1 RAF1 LOC103090072 LOC103090072 SERPINB5 SERPINB5 GDF7 GDF7 RB1CC1 RB1CC1 PLAG1 PLAG1 CADM1 CADM1 CACNB4 CACNB4 LAMA5 LAMA5 FASN FASN CCDC40 CCDC40 MAN2A1 MAN2A1 LOC103077930 LOC103077930 SCRIB SCRIB HNF4A HNF4A HNF1B HNF1B ADA ADA BCL2 BCL2 FA2H FA2H TBX2 TBX2 NOG NOG HOXB13 HOXB13 EGF EGF MED1 MED1 LOC103088309 LOC103088309 LOC103084351 LOC103084351 FRS2 FRS2 SMAD4 SMAD4 NFKB1 NFKB1 VDR VDR SRP54 SRP54 FADD FADD HOXA13 HOXA13 CDK5RAP3 CDK5RAP3 HOXA9 HOXA9 POU3F2 POU3F2 HLX HLX CTNNB1 CTNNB1 MSX1 MSX1 NKX2-5 NKX2-5 NFIB NFIB LOC103081266 LOC103081266 MAFB MAFB FOXA1 FOXA1 SEMA3C SEMA3C PIK3CA PIK3CA LOC103081163 LOC103081163 LOC103072712 LOC103072712 HOXB9 HOXB9 PLXNA1 PLXNA1 WNT3 WNT3 CITED2 CITED2 GATA3 GATA3 CCND1 CCND1 AGAP2 AGAP2 GLI1 GLI1 HOXA3 HOXA3 HOXA5 HOXA5 GHRHR GHRHR GCM2 GCM2 BRAF BRAF HGF HGF GLI3 GLI3 SOCS2 SOCS2 MAD1L1 MAD1L1 FOXF1 FOXF1 STAT6 STAT6 EZH2 EZH2 PHB2 PHB2 ERBB4 ERBB4 LOC103077051 LOC103077051 NEURL1 NEURL1 TNFSF11 TNFSF11 FGF2 FGF2 CCDC39 CCDC39 CLCN2 CLCN2 CEBPG CEBPG BMP2 BMP2 LSR LSR EPHB3 EPHB3 CREB1 CREB1 SOSTDC1 SOSTDC1 EDA EDA GSX1 GSX1 SIX4 SIX4 CDKN1B CDKN1B FGF8 FGF8 BCL2L11 BCL2L11 SMO SMO ISL1 ISL1 EDNRA EDNRA BTRC BTRC NKX2-3 NKX2-3 TGFB2 TGFB2 SIX1 SIX1 HIF1A HIF1A LOC103082395 LOC103082395 PCSK9 PCSK9 SLC6A3 SLC6A3 LOC103078457 LOC103078457 DKK3 DKK3 PDX1 PDX1 RIPK3 RIPK3 LOC103086063 LOC103086063
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
USF2Upstream stimulatory factor 2 isoform X1. (356 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
PAX8Paired box protein Pax-8. (288 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
SULF2Extracellular sulfatase Sulf-2 isoform X2. (857 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
LOC103070587Tyrosine-protein kinase ABL1-like. (126 aa)
ARAndrogen receptor. (888 aa)
LOC103087942Signal transducer and activator of transcription 5A-like. (237 aa)
FEM1BProtein fem-1 homolog B. (627 aa)
SRCTyrosine-protein kinase. (548 aa)
LOC103068298Prolactin-like isoform X1. (230 aa)
STAT5BSignal transducer and activator of transcription. (792 aa)
EDN1Endothelin-1. (202 aa)
MST1Hepatocyte growth factor-like protein; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
ALDH1A3Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
ORAI1Calcium release-activated calcium channel protein 1. (303 aa)
MSNMoesin. (577 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
LOC103082450UPF0762 protein C6orf58 homolog. (341 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
RXFP1Relaxin receptor 1 isoform X1. (758 aa)
STRA6Stimulated by retinoic acid gene 6 protein homolog isoform X2. (675 aa)
PMLProtein PML. (848 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
LOC103087126AT-rich interactive domain-containing protein 5B-like. (941 aa)
BMP7Bone morphogenetic protein 7 isoform X1. (431 aa)
ASXL1Putative Polycomb group protein ASXL1. (1544 aa)
SEC63Translocation protein SEC63 homolog. (760 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial. (421 aa)
ZNF330Zinc finger protein 330. (320 aa)
IL6LOW QUALITY PROTEIN: interleukin-6. (243 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (553 aa)
TGM2Protein-glutamine gamma-glutamyltransferase 2 isoform X1. (687 aa)
GHRHSomatoliberin isoform X1. (106 aa)
COBLProtein cordon-bleu. (1698 aa)
PCK2Phosphoenolpyruvate carboxykinase [GTP], mitochondrial. (640 aa)
LRP5Low-density lipoprotein receptor-related protein 5. (1451 aa)
EAF2ELL-associated factor 2. (264 aa)
LOC103082172UPF0762 protein C6orf58-like. (281 aa)
ARID5BAT-rich interactive domain-containing protein 5B. (327 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
HNF1AHepatocyte nuclear factor 1-alpha. (632 aa)
PTCH1Protein patched homolog 1 isoform X1. (1448 aa)
RARGRetinoic acid receptor gamma isoform X1. (458 aa)
ZNF703Zinc finger protein 703. (584 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
GATA6Transcription factor GATA-6-like. (592 aa)
LOC103085851Transcription factor GATA-6-like. (426 aa)
WDR77Methylosome protein 50 isoform X1. (342 aa)
DDX55RNA helicase. (600 aa)
MKI67Antigen KI-67. (2385 aa)
E2F7Transcription factor E2F7. (905 aa)
PROX1Prospero homeobox protein 1. (737 aa)
SLC46A2Thymic stromal cotransporter homolog. (475 aa)
CRKLCrk-like protein. (303 aa)
DDR1Tyrosine-protein kinase receptor. (923 aa)
HOXD9Homeobox protein Hox-D9. (345 aa)
IRS2Insulin receptor substrate 2. (1362 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
CSN3Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family. (181 aa)
NR5A1Steroidogenic factor 1 isoform X1. (461 aa)
TNCTenascin isoform X1. (2200 aa)
NF1Neurofibromin isoform X1. (2841 aa)
HESX1Homeobox expressed in ES cells 1. (186 aa)
PKD2LOW QUALITY PROTEIN: polycystin-2. (963 aa)
CUL3Cullin-3; Belongs to the cullin family. (653 aa)
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (224 aa)
ZIC3LOW QUALITY PROTEIN: zinc finger protein ZIC 3. (468 aa)
FOXN1Forkhead box protein N1. (645 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
HOXD3Homeobox protein Hox-D3. (432 aa)
DNAAF1Dynein assembly factor 1, axonemal. (641 aa)
UPF2Regulator of nonsense transcripts 2. (1259 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (444 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
IRF6Interferon regulatory factor 6 isoform X1. (467 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
HOXD13Homeobox protein Hox-D13. (344 aa)
GFERSulfhydryl oxidase. (206 aa)
NPHP3Nephrocystin-3-like. (496 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (750 aa)
AIREAutoimmune regulator. (562 aa)
ASCL1Achaete-scute homolog 1. (227 aa)
SOX10Transcription factor SOX-10 isoform X1. (468 aa)
SOX9Transcription factor SOX-9 isoform X1. (509 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
DRD2D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
TCF21LOW QUALITY PROTEIN: transcription factor 21. (179 aa)
IGSF3Immunoglobulin superfamily member 3-like. (1191 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (946 aa)
TGFAProtransforming growth factor alpha. (145 aa)
ARMC5Armadillo repeat-containing protein 5. (942 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
ONECUT2One cut domain family member 2. (320 aa)
AGPAT6Glycerol-3-phosphate acyltransferase 4. (456 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
SERPINF1Pigment epithelium-derived factor isoform X1; Belongs to the serpin family. (437 aa)
PKD1Polycystin-1. (4305 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PAX1Paired box protein Pax-1. (450 aa)
CSMD2CUB and sushi domain-containing protein 2. (3546 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (165 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
EDARTumor necrosis factor receptor superfamily member EDAR. (448 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (365 aa)
ANXA1Annexin. (346 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
NODALNodal homolog. (349 aa)
PTCD2Pentatricopeptide repeat-containing protein 2, mitochondrial isoform X1. (387 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
LOC103088284LOW QUALITY PROTEIN: selenoprotein H. (122 aa)
NOTCH2Neurogenic locus notch homolog protein 2-like. (2471 aa)
LOC103070918Nephrocystin-3-like. (825 aa)
E2F8LOW QUALITY PROTEIN: transcription factor E2F8. (869 aa)
ELF3ETS-related transcription factor Elf-3. (372 aa)
CTC1CST complex subunit CTC1. (1210 aa)
SFRP1Secreted frizzled-related protein 1. (308 aa)
ASH1LHistone-lysine N-methyltransferase ASH1L. (2964 aa)
PYGO2Pygopus homolog 2. (406 aa)
BCL11BB-cell lymphoma/leukemia 11B isoform X1. (902 aa)
LOC103085888Corticotropin-releasing factor receptor 1-like. (129 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform-like isoform X1. (613 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (464 aa)
CCL11C-C motif chemokine. (99 aa)
SRFSerum response factor. (510 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (875 aa)
TWSG1Twisted gastrulation protein homolog 1. (222 aa)
ARHGAP35Rho GTPase-activating protein 35. (1500 aa)
KDM5BLysine-specific demethylase 5B. (1352 aa)
TFCP2L1Transcription factor CP2-like protein 1. (479 aa)
NKX3-1Homeobox protein Nkx-3.1 isoform X1. (245 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
LATS1Serine/threonine-protein kinase LATS1. (1128 aa)
LOC103090152Forkhead box protein B1-like. (275 aa)
HES1Transcription factor HES-1. (280 aa)
ZBTB7BZinc finger and BTB domain-containing protein 7B. (543 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
BSXBrain-specific homeobox protein homolog. (232 aa)
LOC103079308Uncharacterized protein LOC103079308. (289 aa)
TGFB3Transforming growth factor beta-3. (456 aa)
LOC103088556Aldehyde dehydrogenase, mitochondrial-like; Belongs to the aldehyde dehydrogenase family. (468 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A. (850 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
IQGAP3Ras GTPase-activating-like protein IQGAP3. (1612 aa)
FOXB1Forkhead box protein B1-like. (325 aa)
NTN1Netrin-1 isoform X1. (604 aa)
LOC103075733Adenine deaminase-like. (315 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
LRRC1Leucine-rich repeat-containing protein 1. (524 aa)
SALL1LOW QUALITY PROTEIN: sal-like protein 1. (1317 aa)
WT1Wilms tumor protein isoform X1. (450 aa)
PAX6Paired box protein Pax-6 isoform X1. (436 aa)
TPH1Tryptophan 5-hydroxylase 1. (444 aa)
LOC103081416Transcription factor Sp3-like. (1043 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
LHX3LIM/homeobox protein Lhx3 isoform X1. (403 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2536 aa)
SERPINE2Glia-derived nexin isoform X2; Belongs to the serpin family. (398 aa)
RPGRIP1LProtein fantom isoform X1. (1292 aa)
NOTCH4Neurogenic locus notch homolog protein 4. (1993 aa)
FOXE1Forkhead box protein E1. (373 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
APOA1Apolipoprotein A-I. (265 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
ONECUT1One cut domain family member. (464 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
RELATranscription factor p65 isoform X1. (560 aa)
PRKCSHGlucosidase 2 subunit beta isoform X1. (534 aa)
ZBTB1Zinc finger and BTB domain-containing protein 1. (713 aa)
FGL1Fibrinogen-like protein 1 isoform X1. (315 aa)
RHBDD3Rhomboid domain-containing protein 3. (386 aa)
JARID2LOW QUALITY PROTEIN: protein Jumonji. (1237 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (337 aa)
PITX1Homeobox protein. (312 aa)
STK11Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily. (438 aa)
PLXND1plexin-D1. (1747 aa)
LOC103078858Adenine deaminase-like. (322 aa)
ESRP2Epithelial splicing regulatory protein 2. (717 aa)
AREGAmphiregulin isoform X1. (254 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LOC103090072Cyclic AMP-responsive element-binding protein 1-like. (47 aa)
SERPINB5Serpin B5; Belongs to the serpin family. (375 aa)
GDF7Growth/differentiation factor 7. (457 aa)
RB1CC1RB1-inducible coiled-coil protein 1. (1589 aa)
PLAG1Zinc finger protein PLAG1 isoform X1. (499 aa)
CADM1Cell adhesion molecule 1 isoform X1. (472 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (519 aa)
LAMA5Laminin subunit alpha-5. (3689 aa)
FASNFatty acid synthase. (2515 aa)
CCDC40Coiled-coil domain-containing protein 40. (1130 aa)
MAN2A1Alpha-mannosidase. (1145 aa)
LOC103077930Thyroid transcription factor 1-like isoform X2. (402 aa)
SCRIBLOW QUALITY PROTEIN: protein scribble homolog. (1659 aa)
HNF4AHepatocyte nuclear factor 4-alpha isoform X1. (474 aa)
HNF1BHepatocyte nuclear factor 1-beta isoform X1. (557 aa)
ADAAdenosine deaminase. (363 aa)
BCL2Apoptosis regulator Bcl-2. (232 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
TBX2T-box transcription factor TBX2. (875 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HOXB13Homeobox protein Hox-B13. (285 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1579 aa)
LOC103088309Homeobox protein prophet of Pit-1-like. (226 aa)
LOC103084351LOW QUALITY PROTEIN: T-box transcription factor TBX3-like. (737 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (977 aa)
VDRVitamin D3 receptor isoform X1. (427 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
HOXA13Homeobox protein Hox-A13. (297 aa)
CDK5RAP3CDK5 regulatory subunit-associated protein 3. (505 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (273 aa)
POU3F2POU domain protein. (439 aa)
HLXH2.0-like homeobox protein. (483 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
MSX1Homeobox protein MSX-1. (303 aa)
NKX2-5Homeobox protein Nkx-2.5. (324 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (576 aa)
LOC103081266Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
MAFBTranscription factor MafB. (277 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (466 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
LOC103081163Nucleoside diphosphate kinase. (152 aa)
LOC103072712Mitotic spindle assembly checkpoint protein MAD1-like. (330 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
PLXNA1plexin-A1. (1890 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
CITED2Cbp/p300-interacting transactivator 2 isoform X1. (272 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
AGAP2arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2-like isoform X1. (1193 aa)
GLI1Zinc finger protein GLI1 isoform X1. (1106 aa)
HOXA3Homeobox protein Hox-A3. (385 aa)
HOXA5Homeobox protein Hox-A5. (270 aa)
GHRHRGrowth hormone-releasing hormone receptor isoform X1; Belongs to the G-protein coupled receptor 2 family. (452 aa)
GCM2Chorion-specific transcription factor GCMb. (505 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
GLI3Transcriptional activator GLI3. (1590 aa)
SOCS2Suppressor of cytokine signaling 2 isoform X1. (198 aa)
MAD1L1Mitotic spindle assembly checkpoint protein MAD1. (582 aa)
FOXF1Forkhead box protein F1. (377 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X1. (751 aa)
PHB2Prohibitin. (299 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
LOC103077051CUB and sushi domain-containing protein 1-like. (431 aa)
NEURL1E3 ubiquitin-protein ligase NEURL1. (574 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
CCDC39Coiled-coil domain-containing protein 39. (941 aa)
CLCN2Chloride channel protein 2 isoform X1. (904 aa)
CEBPGCCAAT/enhancer-binding protein gamma. (149 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
LSRLipolysis-stimulated lipoprotein receptor isoform X1. (577 aa)
EPHB3Ephrin type-B receptor 3. (1005 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (293 aa)
SOSTDC1Sclerostin domain-containing protein 1. (206 aa)
EDAectodysplasin-A isoform X1; Belongs to the tumor necrosis factor family. (391 aa)
GSX1GS homeobox 1. (263 aa)
SIX4Homeobox protein SIX4-like. (786 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (196 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
EDNRAEndothelin-1 receptor isoform X2. (318 aa)
BTRCF-box/WD repeat-containing protein 1A. (579 aa)
NKX2-3Homeobox protein Nkx-2.3. (365 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SIX1Homeobox protein SIX1. (284 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X2. (822 aa)
LOC103082395Homeobox protein SIX4-like. (300 aa)
PCSK9LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 9. (659 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
LOC103078457Homeobox protein orthopedia-like. (331 aa)
DKK3Dickkopf-related protein 3 isoform X1. (349 aa)
PDX1Pancreas/duodenum homeobox protein 1. (286 aa)
RIPK3LOW QUALITY PROTEIN: receptor-interacting serine-threonine kinase 3. (396 aa)
LOC103086063Homeobox protein orthopedia-like. (267 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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