41 items (Lipotes vexillifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HTR2C	5-hydroxytryptamine receptor 2C. (458 aa)
	MCOLN3	Mucolipin-3 isoform X1. (552 aa)
	BBC3	Bcl-2-binding component 3. (193 aa)
	MCOLN2	Mucolipin-2. (566 aa)
	FKBP1B	Peptidylprolyl isomerase. (108 aa)
	ITPR1	Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
	TRPM2	Transient receptor potential cation channel subfamily M member 2. (1499 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
	RYR2	Ryanodine receptor 2-like. (4986 aa)
	PKD2	LOW QUALITY PROTEIN: polycystin-2. (963 aa)
	NOL3	Nucleolar protein 3. (202 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
	FASLG	Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa)
	ITPR2	Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
	IBTK	LOW QUALITY PROTEIN: inhibitor of Bruton tyrosine kinase. (1360 aa)
	ERO1L	ERO1-like protein alpha. (468 aa)
	PTPRC	Receptor-type tyrosine-protein phosphatase C. (1121 aa)
	CCL21	c-C motif chemokine 21. (131 aa)
	XCR1	Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family. (333 aa)
	CCR5	c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	RYR1	Ryanodine receptor 1 isoform X2. (5032 aa)
	TPCN1	Two pore calcium channel protein 1 isoform X1. (817 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
	SLC8B1	Sodium/potassium/calcium exchanger 6, mitochondrial isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (600 aa)
	TPCN2	Two pore calcium channel protein 2. (758 aa)
	LETM1	LETM1 and EF-hand domain-containing protein 1, mitochondrial. (908 aa)
	DDIT3	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (469 aa)
	GP9	Platelet glycoprotein IX. (177 aa)
	RYR3	Ryanodine receptor 3. (4869 aa)
	F2R	Proteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (428 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
	CHERP	Calcium homeostasis endoplasmic reticulum protein. (913 aa)
	HTR2B	5-hydroxytryptamine receptor 2B. (537 aa)
	GP1BB	Platelet glycoprotein Ib beta chain. (205 aa)
	TMEM38B	Trimeric intracellular cation channel type B. (291 aa)
	TMEM38A	Trimeric intracellular cation channel type A. (299 aa)
	MCOLN1	Mucolipin-1 isoform X1. (580 aa)
	GP1BA	Platelet glycoprotein Ib alpha chain. (584 aa)
	CCL3	LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3. (88 aa)
	CCL19	C-C motif chemokine. (100 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL19	CCL21	A0A340YHA4	A0A340YFK4	C-C motif chemokine.	c-C motif chemokine 21.	0.920
CCL19	CCL3	A0A340YHA4	A0A340YI23	C-C motif chemokine.	LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3.	0.573
CCL19	CCR5	A0A340YHA4	A0A340YCY4	C-C motif chemokine.	c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.824
CCL19	XCR1	A0A340YHA4	A0A340YE84	C-C motif chemokine.	Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.720
CCL21	CCL19	A0A340YFK4	A0A340YHA4	c-C motif chemokine 21.	C-C motif chemokine.	0.920
CCL21	CCL3	A0A340YFK4	A0A340YI23	c-C motif chemokine 21.	LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3.	0.614
CCL21	CCR5	A0A340YFK4	A0A340YCY4	c-C motif chemokine 21.	c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.898
CCL21	XCR1	A0A340YFK4	A0A340YE84	c-C motif chemokine 21.	Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.760
CCL3	CCL19	A0A340YI23	A0A340YHA4	LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3.	C-C motif chemokine.	0.573
CCL3	CCL21	A0A340YI23	A0A340YFK4	LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3.	c-C motif chemokine 21.	0.614
CCL3	CCR5	A0A340YI23	A0A340YCY4	LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3.	c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	0.995
CCL3	FGF2	A0A340YI23	A0A340YAR7	LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.483
CCL3	XCR1	A0A340YI23	A0A340YE84	LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3.	Chemokine XC receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.759
CCR5	CCL19	A0A340YCY4	A0A340YHA4	c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.824
CCR5	CCL21	A0A340YCY4	A0A340YFK4	c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	c-C motif chemokine 21.	0.898
CCR5	CCL3	A0A340YCY4	A0A340YI23	c-C chemokine receptor type 5; Belongs to the G-protein coupled receptor 1 family.	LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3.	0.995
FGF2	CCL3	A0A340YAR7	A0A340YI23	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3.	0.483
FKBP1B	RYR1	A0A340X6D3	A0A340YBR0	Peptidylprolyl isomerase.	Ryanodine receptor 1 isoform X2.	0.995
FKBP1B	RYR2	A0A340X6D3	A0A340WVG9	Peptidylprolyl isomerase.	Ryanodine receptor 2-like.	0.978
FKBP1B	RYR3	A0A340X6D3	A0A340XTF8	Peptidylprolyl isomerase.	Ryanodine receptor 3.	0.749