STRINGSTRING
LOC103079903 LOC103079903 TYW1B TYW1B EXO5 EXO5 IREB2 IREB2 RSAD2 RSAD2 NDUFS1 NDUFS1 LOC103071534 LOC103071534 CIAPIN1 CIAPIN1 INO80D INO80D LOC103089404 LOC103089404 CDK5RAP1 CDK5RAP1 PRIM2 PRIM2 LOC103090476 LOC103090476 NDUFS2 NDUFS2 LOC103071438 LOC103071438 DPH2 DPH2 LOC103070884 LOC103070884 ELP3 ELP3 LOC103073812 LOC103073812 RSAD1 RSAD1 ACO1 ACO1 LOC103078414 LOC103078414 POLD1 POLD1 LOC103073537 LOC103073537 LOC103091132 LOC103091132 LOC103084906 LOC103084906 LOC103081531 LOC103081531 LOC103084998 LOC103084998 NUBP1 NUBP1 RTEL1 RTEL1 DPYD DPYD LOC103079874 LOC103079874 NDUFS7 NDUFS7 ISCA2 ISCA2 LOC103071209 LOC103071209 LOC103075095 LOC103075095 ERCC2 ERCC2 LOC103088827 LOC103088827 SDHB SDHB DNA2 DNA2 MOCS1 MOCS1 LOC103078091 LOC103078091 LOC103069833 LOC103069833 LOC103088015 LOC103088015 CDKAL1 CDKAL1 POLE POLE DPH1 DPH1 ACO2 ACO2 LOC103074876 LOC103074876 NUBP2 NUBP2 LOC103080022 LOC103080022 TYW1 TYW1 NARFL NARFL NTHL1 NTHL1 NFU1 NFU1 MUTYH MUTYH NDUFV1 NDUFV1 NDUFS8 NDUFS8 LOC103068323 LOC103068323 LIAS LIAS LOC103078914 LOC103078914 LOC103084019 LOC103084019 LOC103075137 LOC103075137 ETFDH ETFDH LOC103080068 LOC103080068 LOC103073807 LOC103073807 LOC103087502 LOC103087502
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103079903Iron-sulfur protein NUBPL-like. (402 aa)
TYW1BS-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase. (531 aa)
EXO5LOW QUALITY PROTEIN: exonuclease 5. (372 aa)
IREB2Iron-responsive element-binding protein 2; Belongs to the aconitase/IPM isomerase family. (964 aa)
RSAD2Radical S-adenosyl methionine domain-containing protein 2. (362 aa)
NDUFS1NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1; Belongs to the complex I 75 kDa subunit family. (727 aa)
LOC103071534Putative septum site-determining protein MinD-like. (301 aa)
CIAPIN1Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (310 aa)
INO80DLOW QUALITY PROTEIN: INO80 complex subunit D. (1032 aa)
LOC103089404Uncharacterized protein LOC103089404. (568 aa)
CDK5RAP1LOW QUALITY PROTEIN: CDK5 regulatory subunit associated protein 1. (539 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (506 aa)
LOC103090476Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial-like. (520 aa)
NDUFS2NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; Belongs to the complex I 49 kDa subunit family. (463 aa)
LOC103071438Phosphomethylpyrimidine synthase, chloroplastic-like. (341 aa)
DPH22-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2. (489 aa)
LOC103070884Iron-sulfur assembly protein IscA-like 2, mitochondrial-like. (132 aa)
ELP3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (547 aa)
LOC103073812NAD(P)H-quinone oxidoreductase subunit H, chloroplastic-like; Belongs to the complex I 49 kDa subunit family. (246 aa)
RSAD1Radical S-adenosyl methionine domain-containing protein; May be a heme chaperone, appears to bind heme. Homologous bacterial proteins do not have oxygen-independent coproporphyrinogen- III oxidase activity. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L- methionine; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (514 aa)
ACO1Cytoplasmic aconitate hydratase isoform X1; Belongs to the aconitase/IPM isomerase family. (902 aa)
LOC103078414Aconitate hydratase, cytoplasmic-like. (836 aa)
POLD1DNA polymerase. (1107 aa)
LOC103073537NADH-ubiquinone oxidoreductase 20 kDa subunit-like; Belongs to the complex I 20 kDa subunit family. (225 aa)
LOC103091132Biotin synthase-like. (351 aa)
LOC103084906Aconitate hydratase 1-like. (863 aa)
LOC103081531Putative septum site-determining protein MinD-like. (274 aa)
LOC103084998CDK5RAP1-like protein-like. (442 aa)
NUBP1Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (320 aa)
RTEL1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1249 aa)
DPYDDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1025 aa)
LOC103079874Iron-sulfur protein NUBPL-like. (168 aa)
NDUFS7NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Belongs to the complex I 20 kDa subunit family. (231 aa)
ISCA2Iron-sulfur cluster assembly 2 homolog, mitochondrial. (154 aa)
LOC103071209Iron-sulfur protein NUBPL-like. (363 aa)
LOC103075095Biotin synthase-like. (282 aa)
ERCC2TFIIH basal transcription factor complex helicase XPD subunit isoform X1. (760 aa)
LOC103088827Molybdenum cofactor biosynthesis protein 1-like. (249 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
DNA2DNA replication ATP-dependent helicase/nuclease DNA2. (1063 aa)
MOCS1Molybdenum cofactor biosynthesis protein 1-like. (385 aa)
LOC103078091Putative septum site-determining protein MinD-like. (489 aa)
LOC103069833Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (338 aa)
LOC103088015Phosphomethylpyrimidine synthase, chloroplastic-like. (591 aa)
CDKAL1Threonylcarbamoyladenosine tRNA methylthiotransferase. (627 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2283 aa)
DPH12-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (438 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)
LOC103074876Biotin synthase-like. (351 aa)
NUBP2Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (271 aa)
LOC103080022Succinate dehydrogenase [ubiquinone] iron-sulfur subunit 1, mitochondrial-like. (234 aa)
TYW1S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase. (279 aa)
NARFLCytosolic Fe-S cluster assembly factor NARFL; Belongs to the NARF family. (476 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (304 aa)
NFU1NFU1 iron-sulfur cluster scaffold homolog, mitochondrial. (253 aa)
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (524 aa)
NDUFV1NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa)
NDUFS8NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial. (213 aa)
LOC103068323Aconitate hydratase, cytoplasmic-like; Belongs to the aconitase/IPM isomerase family. (807 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa)
LOC103078914NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (399 aa)
LOC103084019Iron-sulfur protein NUBPL-like. (202 aa)
LOC103075137Iron-sulfur protein NUBPL-like. (104 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (617 aa)
LOC103080068Molybdenum cofactor biosynthesis protein 1-like. (144 aa)
LOC103073807Cytoplasmic aconitate hydratase-like. (1120 aa)
LOC103087502Uncharacterized protein LOC103087502. (776 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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