STRINGSTRING
PFN2 PFN2 LOC103070824 LOC103070824 ADRA2A ADRA2A TOR1A TOR1A DVL1 DVL1 P2RX7 P2RX7 CPLX3 CPLX3 ADCY1 ADCY1 ATP2A2 ATP2A2 CACNB2 CACNB2 BACE1 BACE1 HCRT HCRT CSPG5 CSPG5 LRRK2 LRRK2 SYNPR SYNPR SNCAIP SNCAIP GSK3B GSK3B PRKCB PRKCB SYP SYP RAP1A RAP1A FLOT1 FLOT1 ASIC1 ASIC1 NF1 NF1 CPLX4 CPLX4 SYT1 SYT1 SYT12 SYT12 STXBP5L STXBP5L GIT1 GIT1 PNKD PNKD BAIAP3 BAIAP3 SLC4A8 SLC4A8 STX1B STX1B DRD2 DRD2 ACTN1 ACTN1 STXBP5 STXBP5 GDNF GDNF CASK CASK SYT2 SYT2 GRIN3A GRIN3A SNAPIN SNAPIN ITGB3 ITGB3 GPM6B GPM6B PARK2 PARK2 PREPL PREPL GIPC3 GIPC3 LOC103077822 LOC103077822 GIPC2 GIPC2 DTNBP1 DTNBP1 RAB3B RAB3B VPS18 VPS18 ADORA2B ADORA2B RAP1B RAP1B CACNB4 CACNB4 MCTP2 MCTP2 NLGN1 NLGN1 FBXL20 FBXL20 CPLX2 CPLX2 APBA1 APBA1 GPER1 GPER1 SLC17A8 SLC17A8 CHRM2 CHRM2 LOC103087242 LOC103087242 DGKI DGKI BRAF BRAF STX1A STX1A LOC103083735 LOC103083735 GIPC1 GIPC1 LOC103088976 LOC103088976 MCTP1 MCTP1 CNR1 CNR1 RAB5A RAB5A CHRNA5 CHRNA5 ITGB1 ITGB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PFN2Profilin; Belongs to the profilin family. (143 aa)
LOC103070824Leucine-rich repeat serine/threonine-protein kinase 2-like. (1609 aa)
ADRA2Aalpha-2A adrenergic receptor. (462 aa)
TOR1ALOW QUALITY PROTEIN: torsin-1A. (419 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X2. (699 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
CPLX3Complexin-3. (158 aa)
ADCY1Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1134 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1039 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (651 aa)
BACE1Beta-secretase 1 isoform X1; Belongs to the peptidase A1 family. (498 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (131 aa)
CSPG5LOW QUALITY PROTEIN: chondroitin sulfate proteoglycan 5. (572 aa)
LRRK2Leucine-rich repeat serine/threonine-protein kinase 2-like. (920 aa)
SYNPRSynaptoporin isoform X1. (276 aa)
SNCAIPSynphilin-1 isoform X1. (968 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (433 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
SYPSynaptophysin. (313 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (427 aa)
ASIC1Acid-sensing ion channel 1 isoform X1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (574 aa)
NF1Neurofibromin isoform X1. (2841 aa)
CPLX4Complexin-4. (159 aa)
SYT1Synaptotagmin-1 isoform X1. (422 aa)
SYT12Synaptotagmin-12 isoform X1. (421 aa)
STXBP5LSyntaxin-binding protein 5-like. (1115 aa)
GIT1ARF GTPase-activating protein GIT1 isoform X1. (770 aa)
PNKDProbable hydrolase PNKD isoform X1. (383 aa)
BAIAP3BAI1-associated protein 3 isoform X1. (1152 aa)
SLC4A8Anion exchange protein. (1092 aa)
STX1Bsyntaxin-1B isoform X2; Belongs to the syntaxin family. (291 aa)
DRD2D(2) dopamine receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
ACTN1Alpha-actinin-1 isoform X1. (914 aa)
STXBP5LOW QUALITY PROTEIN: syntaxin-binding protein 5. (1154 aa)
GDNFGlial cell line-derived neurotrophic factor isoform X1. (211 aa)
CASKPeripheral plasma membrane protein CASK isoform X2; Belongs to the MAGUK family. (926 aa)
SYT2Synaptotagmin-2 isoform X1. (422 aa)
GRIN3AGlutamate receptor ionotropic, NMDA 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1115 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
GPM6BNeuronal membrane glycoprotein M6-b isoform X6. (324 aa)
PARK2RBR-type E3 ubiquitin transferase. (274 aa)
PREPLProlyl endopeptidase-like isoform X1. (727 aa)
GIPC3PDZ domain-containing protein GIPC3. (318 aa)
LOC103077822Profilin; Belongs to the profilin family. (127 aa)
GIPC2PDZ domain-containing protein GIPC2. (311 aa)
DTNBP1Dysbindin. (341 aa)
RAB3BRas-related protein Rab-3B. (219 aa)
VPS18Vacuolar protein sorting-associated protein 18 homolog. (973 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (333 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform X1. (519 aa)
MCTP2Multiple C2 and transmembrane domain-containing protein 2-like. (861 aa)
NLGN1Neuroligin-1 isoform X1. (863 aa)
FBXL20F-box/LRR-repeat protein 20 isoform X1. (436 aa)
CPLX2Complexin-2. (134 aa)
APBA1Amyloid beta A4 precursor protein-binding family A member 1-like. (843 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
SLC17A8Vesicular glutamate transporter 3 isoform X1. (589 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
LOC103087242Profilin; Belongs to the profilin family. (134 aa)
DGKIDiacylglycerol kinase. (1078 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
STX1Asyntaxin-1A; Belongs to the syntaxin family. (288 aa)
LOC103083735E3 ubiquitin-protein ligase parkin-like. (141 aa)
GIPC1PDZ domain-containing protein GIPC1 isoform X1. (333 aa)
LOC103088976Ras-related protein Rap-1b-like isoform X1. (165 aa)
MCTP1Multiple C2 and transmembrane domain-containing protein 1 isoform X1. (999 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
RAB5ARas-related protein Rab-5A isoform X1. (215 aa)
CHRNA5Neuronal acetylcholine receptor subunit alpha-5. (475 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (805 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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