STRINGSTRING
NPRL3 NPRL3 BCOR BCOR MMP25 MMP25 LEF1 LEF1 TCF21 TCF21 SGPL1 SGPL1 WFIKKN1 WFIKKN1 PDGFRA PDGFRA JAG2 JAG2 SCHIP1 SCHIP1 HAND2 HAND2 LOC103076632 LOC103076632 WNT3A WNT3A DLG2 DLG2 ITGB8 ITGB8 SHH SHH ALX4 ALX4 CHD7 CHD7 EPHB3 EPHB3 VAX1 VAX1 CSRNP1 CSRNP1 LOC103080655 LOC103080655 LOC103072080 LOC103072080 GLI3 GLI3 SATB2 SATB2 INHBA INHBA TFAP2A TFAP2A PAK1IP1 PAK1IP1 BNC2 BNC2 DLG1 DLG1 GDF11 GDF11 WNT9B WNT9B WFIKKN2 WFIKKN2 MSX1 MSX1 WDPCP WDPCP COL2A1 COL2A1 MEOX2 MEOX2 OSR1 OSR1 SMAD4 SMAD4 OSR2 OSR2 TBC1D32 TBC1D32 LOC103083860 LOC103083860 FRAS1 FRAS1 TMEM107 TMEM107 INSIG2 INSIG2 PYGO2 PYGO2 BMPR1A BMPR1A WNT5A WNT5A PRRX1 PRRX1 LOC103079308 LOC103079308 INSIG1 INSIG1 LOC103088826 LOC103088826 TIPARP TIPARP EPHB2 EPHB2 FOXE1 FOXE1 TGFBR1 TGFBR1 ANP32B ANP32B WNT11 WNT11 MSC MSC LRRC32 LRRC32 DHRS3 DHRS3 TBX2 TBX2 LOC103084351 LOC103084351 INTU INTU LOC103081990 LOC103081990 PKDCC PKDCC SOS1 SOS1 SNAI1 SNAI1 LOC103087126 LOC103087126 ARID5B ARID5B DLX5 DLX5 TSHZ1 TSHZ1 FOXF2 FOXF2 IRF6 IRF6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NPRL3Nitrogen permease regulator 3-like protein isoform X2. (582 aa)
BCORLOW QUALITY PROTEIN: BCL-6 corepressor. (1720 aa)
MMP25Matrix metalloproteinase-25. (552 aa)
LEF1Lymphoid enhancer-binding factor 1 isoform X1. (399 aa)
TCF21LOW QUALITY PROTEIN: transcription factor 21. (179 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (568 aa)
WFIKKN1WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1. (549 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1234 aa)
SCHIP1Schwannomin-interacting protein 1 isoform X1. (560 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (165 aa)
LOC103076632Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
DLG2Disks large homolog 2-like isoform X1. (905 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (767 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (454 aa)
ALX4Homeobox protein aristaless-like 4. (407 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2305 aa)
EPHB3Ephrin type-B receptor 3. (1005 aa)
VAX1Ventral anterior homeobox 1. (332 aa)
CSRNP1Cysteine/serine-rich nuclear protein 1. (590 aa)
LOC103080655chromodomain-helicase-DNA-binding protein 7-like. (414 aa)
LOC103072080Small ubiquitin-related modifier. (106 aa)
GLI3Transcriptional activator GLI3. (1590 aa)
SATB2LOW QUALITY PROTEIN: DNA-binding protein SATB2. (734 aa)
INHBALOW QUALITY PROTEIN: inhibin beta A chain. (430 aa)
TFAP2ATranscription factor AP-2-alpha isoform X1. (446 aa)
PAK1IP1LOW QUALITY PROTEIN: p21-activated protein kinase-interacting protein 1. (394 aa)
BNC2Zinc finger protein basonuclin-2. (1021 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
GDF11Growth/differentiation factor 11. (404 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
WFIKKN2WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2. (574 aa)
MSX1Homeobox protein MSX-1. (303 aa)
WDPCPWD repeat-containing and planar cell polarity effector protein fritz homolog. (668 aa)
COL2A1Collagen alpha-1(II) chain isoform X1. (1487 aa)
MEOX2Homeobox protein MOX-2. (303 aa)
OSR1Protein odd-skipped-related 1. (267 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
OSR2Protein odd-skipped-related 2 isoform X1. (312 aa)
TBC1D32Protein broad-minded. (1259 aa)
LOC103083860Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (227 aa)
FRAS1Extracellular matrix protein FRAS1. (4012 aa)
TMEM107Transmembrane protein 107 isoform X2. (146 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
PYGO2Pygopus homolog 2. (406 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
PRRX1Paired mesoderm homeobox protein 1 isoform X1. (245 aa)
LOC103079308Uncharacterized protein LOC103079308. (289 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (276 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
TIPARPTCDD-inducible poly [ADP-ribose] polymerase isoform X1. (658 aa)
EPHB2Ephrin type-B receptor 2 isoform X1. (964 aa)
FOXE1Forkhead box protein E1. (373 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
ANP32BAcidic leucine-rich nuclear phosphoprotein 32 family member B. (261 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
MSCMusculin. (198 aa)
LRRC32Leucine-rich repeat-containing protein 32. (703 aa)
DHRS3Short-chain dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
TBX2T-box transcription factor TBX2. (875 aa)
LOC103084351LOW QUALITY PROTEIN: T-box transcription factor TBX3-like. (737 aa)
INTUProtein inturned. (934 aa)
LOC103081990Uncharacterized protein C5orf42 homolog. (3193 aa)
PKDCCProtein kinase domain-containing protein, cytoplasmic. (498 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
SNAI1Zinc finger protein SNAI1. (264 aa)
LOC103087126AT-rich interactive domain-containing protein 5B-like. (941 aa)
ARID5BAT-rich interactive domain-containing protein 5B. (327 aa)
DLX5Homeobox protein DLX-5. (289 aa)
TSHZ1Teashirt homolog 1. (1096 aa)
FOXF2Forkhead box protein F2. (443 aa)
IRF6Interferon regulatory factor 6 isoform X1. (467 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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