STRINGSTRING
ENG ENG LOC103080655 LOC103080655 WHSC1 WHSC1 BMPR2 BMPR2 CITED2 CITED2 SEMA3C SEMA3C EGLN1 EGLN1 SMAD7 SMAD7 NKX2-5 NKX2-5 SMAD4 SMAD4 LOC103084351 LOC103084351 NOG NOG TBX2 TBX2 DHRS3 DHRS3 WNT11 WNT11 TGFBR1 TGFBR1 NOTCH1 NOTCH1 LOC103088826 LOC103088826 CYR61 CYR61 HES1 HES1 WNT5A WNT5A BMPR1A BMPR1A LOC103083860 LOC103083860 NOTCH2 NOTCH2 LOC103076632 LOC103076632 HEYL HEYL APLNR APLNR HAND1 HAND1 LRP2 LRP2 JAG1 JAG1 RBM15 RBM15 PROX1 PROX1 LOC103085851 LOC103085851 GATA6 GATA6 SMAD6 SMAD6 SLIT3 SLIT3 BMP7 BMP7 SAV1 SAV1 MKS1 MKS1 ZFPM2 ZFPM2 HEY2 HEY2 TBX20 TBX20 BMP4 BMP4 ZFPM1 ZFPM1 TBX5 TBX5 LOC103072649 LOC103072649 NRP2 NRP2 FGF8 FGF8 GATA4 GATA4 SMO SMO ISL1 ISL1 CHD7 CHD7 PARVA PARVA DNAH11 DNAH11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENGEndoglin. (661 aa)
LOC103080655chromodomain-helicase-DNA-binding protein 7-like. (414 aa)
WHSC1Histone-lysine N-methyltransferase NSD2 isoform X1. (1358 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
CITED2Cbp/p300-interacting transactivator 2 isoform X1. (272 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
EGLN1Egl nine homolog 1. (400 aa)
SMAD7Mothers against decapentaplegic homolog. (427 aa)
NKX2-5Homeobox protein Nkx-2.5. (324 aa)
SMAD4Mothers against decapentaplegic homolog. (553 aa)
LOC103084351LOW QUALITY PROTEIN: T-box transcription factor TBX3-like. (737 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TBX2T-box transcription factor TBX2. (875 aa)
DHRS3Short-chain dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2536 aa)
LOC103088826Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (143 aa)
CYR61Protein CYR61. (382 aa)
HES1Transcription factor HES-1. (280 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LOC103083860Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (227 aa)
NOTCH2Neurogenic locus notch homolog protein 2-like. (2471 aa)
LOC103076632Frizzled-2-like; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein isoform X1. (323 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4672 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
RBM15Putative RNA-binding protein 15 isoform X1. (1005 aa)
PROX1Prospero homeobox protein 1. (737 aa)
LOC103085851Transcription factor GATA-6-like. (426 aa)
GATA6Transcription factor GATA-6-like. (592 aa)
SMAD6Mothers against decapentaplegic homolog. (495 aa)
SLIT3Slit homolog 3 protein. (1523 aa)
BMP7Bone morphogenetic protein 7 isoform X1. (431 aa)
SAV1Protein salvador homolog 1. (384 aa)
MKS1LOW QUALITY PROTEIN: Meckel syndrome type 1 protein. (562 aa)
ZFPM2Zinc finger protein ZFPM2 isoform X1. (1151 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (352 aa)
TBX20T-box transcription factor TBX20. (449 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
ZFPM1Zinc finger protein ZFPM1. (988 aa)
TBX5T-box transcription factor TBX5 isoform X1. (519 aa)
LOC103072649Dynein heavy chain 11, axonemal-like. (1649 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
GATA4Transcription factor GATA-4. (435 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
CHD7chromodomain-helicase-DNA-binding protein 7. (2305 aa)
PARVAAlpha-parvin. (412 aa)
DNAH11LOW QUALITY PROTEIN: dynein, axonemal, heavy chain 11. (2874 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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