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TNNI3K TNNI3K LOC103089871 LOC103089871 MEF2A MEF2A SLC9A1 SLC9A1 GJA5 GJA5 SCN3B SCN3B AKAP9 AKAP9 KCNE4 KCNE4 KCNJ5 KCNJ5 TRPM4 TRPM4 KCNE1L KCNE1L KCNH6 KCNH6 KCNE3 KCNE3 SLC4A3 SLC4A3 DSP DSP JUP JUP LOC103070794 LOC103070794 KCNQ1 KCNQ1 SCN5A SCN5A LOC103086217 LOC103086217 CACNA2D1 CACNA2D1 CACNA1C CACNA1C TBX5 TBX5 SCN10A SCN10A ISL1 ISL1 SCN1B SCN1B LOC103072657 LOC103072657 KCNH2 KCNH2 KCNA5 KCNA5 KCNE1 KCNE1 CACNB2 CACNB2 NUP155 NUP155 KCNE2 KCNE2 LOC103085837 LOC103085837 KCND3 KCND3 ABCC9 ABCC9 CACNA1D CACNA1D LOC103085751 LOC103085751 KCNN2 KCNN2 CAV1 CAV1 RYR2 RYR2 ZMPSTE24 ZMPSTE24 PKP2 PKP2 PLN PLN KCNJ2 KCNJ2 DSG2 DSG2 GJC1 GJC1 SPTBN4 SPTBN4 SCN2B SCN2B CTNNA3 CTNNA3 SCN4B SCN4B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNNI3KSerine/threonine-protein kinase TNNI3K. (654 aa)
LOC103089871Sulfate/thiosulfate import ATP-binding protein cysA-like. (208 aa)
MEF2AMyocyte-specific enhancer factor 2A isoform X1. (503 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (816 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
SCN3BSodium channel subunit beta-3 isoform X1. (255 aa)
AKAP9A-kinase anchor protein 9. (3874 aa)
KCNE4Potassium voltage-gated channel subfamily E member 4. (170 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4 isoform X1. (419 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1204 aa)
KCNE1LPotassium voltage-gated channel subfamily E member 1-like protein. (145 aa)
KCNH6LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily H member 6. (904 aa)
KCNE3Potassium voltage-gated channel subfamily E member 3. (99 aa)
SLC4A3Anion exchange protein. (1226 aa)
DSPDesmoplakin isoform X1. (2877 aa)
JUPJunction plakoglobin. (330 aa)
LOC103070794Catenin alpha-3-like. (234 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (580 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2020 aa)
LOC103086217Potassium voltage-gated channel subfamily D member 3-like; Belongs to the potassium channel family. (369 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1. (959 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2112 aa)
TBX5T-box transcription factor TBX5 isoform X1. (519 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
SCN1BSodium channel subunit beta-1. (218 aa)
LOC103072657Coxsackievirus and adenovirus receptor homolog. (440 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1198 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (595 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (129 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (651 aa)
NUP155Nuclear pore complex protein Nup155 isoform X1. (1391 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2. (123 aa)
LOC103085837Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4-like. (1200 aa)
KCND3Potassium voltage-gated channel subfamily D member 3. (283 aa)
ABCC9ATP-binding cassette sub-family C member 9 isoform X1. (1549 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
LOC103085751Junction plakoglobin-like. (330 aa)
KCNN2Small conductance calcium-activated potassium channel protein 2 isoform X1. (842 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
RYR2Ryanodine receptor 2-like. (4986 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
PKP2Plakophilin-2. (826 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
KCNJ2Inward rectifier potassium channel 2. (427 aa)
DSG2Desmoglein-2. (1191 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
SPTBN4Spectrin beta chain; Belongs to the spectrin family. (2559 aa)
SCN2BSodium channel subunit beta-2. (215 aa)
CTNNA3Catenin alpha-3. (702 aa)
SCN4BSodium channel subunit beta-4. (228 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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