17 items (Lipotes vexillifer) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	PGAM5	Serine/threonine-protein phosphatase PGAM5, mitochondrial isoform X1. (289 aa)
	CYLD	LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family. (962 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
	MLKL	LOW QUALITY PROTEIN: mixed lineage kinase domain-like protein. (428 aa)
	PPIF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (205 aa)
	NLRP6	LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 6. (1030 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (211 aa)
	TLR3	LOW QUALITY PROTEIN: toll-like receptor 3; Belongs to the Toll-like receptor family. (956 aa)
	RIPK3	LOW QUALITY PROTEIN: receptor-interacting serine-threonine kinase 3. (396 aa)
	FAS	Tumor necrosis factor receptor superfamily member 6. (342 aa)
	FASLG	Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family. (262 aa)
	SPATA2	Spermatogenesis-associated protein 2. (520 aa)
	PYGL	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa)
	IPMK	Kinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa)
	DNM1L	Dynamin-1-like protein isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
	ITPK1	Inositol-tetrakisphosphate 1-kinase. (419 aa)
	TRPM7	Transient receptor potential cation channel subfamily M member 7. (1866 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYLD	FADD	A0A340XDI9	A0A340XXK1	LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.807
CYLD	MLKL	A0A340XDI9	A0A340XNZ0	LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family.	LOW QUALITY PROTEIN: mixed lineage kinase domain-like protein.	0.630
CYLD	RIPK3	A0A340XDI9	A0A340YJU6	LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family.	LOW QUALITY PROTEIN: receptor-interacting serine-threonine kinase 3.	0.667
CYLD	SPATA2	A0A340XDI9	A0A340WH36	LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family.	Spermatogenesis-associated protein 2.	0.991
CYLD	TNF	A0A340XDI9	A0A340XHT2	LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.839
DNM1L	PGAM5	A0A340WZI6	A0A340XC17	Dynamin-1-like protein isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Serine/threonine-protein phosphatase PGAM5, mitochondrial isoform X1.	0.940
DNM1L	RIPK3	A0A340WZI6	A0A340YJU6	Dynamin-1-like protein isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	LOW QUALITY PROTEIN: receptor-interacting serine-threonine kinase 3.	0.917
FADD	CYLD	A0A340XXK1	A0A340XDI9	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family.	0.807
FADD	FAS	A0A340XXK1	A0A340Y9N6	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Tumor necrosis factor receptor superfamily member 6.	0.999
FADD	FASLG	A0A340XXK1	A0A340WH35	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family.	0.939
FADD	MLKL	A0A340XXK1	A0A340XNZ0	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	LOW QUALITY PROTEIN: mixed lineage kinase domain-like protein.	0.824
FADD	RIPK3	A0A340XXK1	A0A340YJU6	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	LOW QUALITY PROTEIN: receptor-interacting serine-threonine kinase 3.	0.995
FADD	TLR3	A0A340XXK1	A0A340XZ05	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	LOW QUALITY PROTEIN: toll-like receptor 3; Belongs to the Toll-like receptor family.	0.554
FADD	TNF	A0A340XXK1	A0A340XHT2	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.803
FAS	FADD	A0A340Y9N6	A0A340XXK1	Tumor necrosis factor receptor superfamily member 6.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.999
FAS	FASLG	A0A340Y9N6	A0A340WH35	Tumor necrosis factor receptor superfamily member 6.	Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family.	0.999
FAS	RIPK3	A0A340Y9N6	A0A340YJU6	Tumor necrosis factor receptor superfamily member 6.	LOW QUALITY PROTEIN: receptor-interacting serine-threonine kinase 3.	0.482
FAS	TNF	A0A340Y9N6	A0A340XHT2	Tumor necrosis factor receptor superfamily member 6.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.659
FASLG	FADD	A0A340WH35	A0A340XXK1	Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.939
FASLG	FAS	A0A340WH35	A0A340Y9N6	Tumor necrosis factor ligand superfamily member 6; Belongs to the tumor necrosis factor family.	Tumor necrosis factor receptor superfamily member 6.	0.999