40 items (Lipotes vexillifer) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	TNFSF11	Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
	RIPK1	Receptor-interacting serine/threonine-protein kinase 1. (523 aa)
	LOC103090748	Zinc finger protein 36, C3H1 type-like 1-like. (226 aa)
	ZFP36L1	Zinc finger protein 36, C3H1 type-like 1-like. (338 aa)
	TF	Serotransferrin; Belongs to the transferrin family. (709 aa)
	CTSH	Pro-cathepsin H isoform X1; Belongs to the peptidase C1 family. (335 aa)
	IQGAP3	Ras GTPase-activating-like protein IQGAP3. (1612 aa)
	NOD2	Nucleotide-binding oligomerization domain-containing protein 2. (1013 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
	MAP2K2	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
	HTR2B	5-hydroxytryptamine receptor 2B. (537 aa)
	KARS	Lysine--tRNA ligase. (625 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
	AVP	Vasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family. (166 aa)
	NOD1	Nucleotide-binding oligomerization domain-containing protein 1. (953 aa)
	SPRY2	Protein sprouty homolog 2 isoform X1. (315 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	BRAF	Serine/threonine-protein kinase B-raf. (763 aa)
	FGF23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (244 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
	SPRY1	Protein sprouty homolog 1 isoform X1. (319 aa)
	ITGAV	Integrin alpha-V; Belongs to the integrin alpha chain family. (1311 aa)
	LOC103070587	Tyrosine-protein kinase ABL1-like. (126 aa)
	ZFP36L2	LOW QUALITY PROTEIN: zinc finger protein 36, C3H1 type-like 2. (487 aa)
	GRB10	Growth factor receptor-bound protein 10 isoform X1. (588 aa)
	EDN1	Endothelin-1. (202 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
	LOC103080627	Lysine--tRNA ligase. (509 aa)
	FLCN	Folliculin. (579 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
	WNK4	Serine/threonine-protein kinase WNK4. (1232 aa)
	MAPK1	Mitogen-activated protein kinase 1 isoform X1. (263 aa)
	HESX1	Homeobox expressed in ES cells 1. (186 aa)
	KDR	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	TBC1D10C	Carabin. (442 aa)
	RAPGEF1	Rap guanine nucleotide exchange factor 1 isoform X1. (1133 aa)
	ABL1	Tyrosine-protein kinase. (1006 aa)
	C1QL4	Complement C1q-like protein 4. (238 aa)
	SOX9	Transcription factor SOX-9 isoform X1. (509 aa)
	MAPK3	Mitogen-activated protein kinase. (325 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	RAPGEF1	A0A340WVZ5	A0A340WUM9	Tyrosine-protein kinase.	Rap guanine nucleotide exchange factor 1 isoform X1.	0.470
AVP	EDN1	A0A340XVS1	A0A340WFW5	Vasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family.	Endothelin-1.	0.489
BRAF	IQGAP3	A0A340Y5C2	A0A340XFE2	Serine/threonine-protein kinase B-raf.	Ras GTPase-activating-like protein IQGAP3.	0.492
BRAF	MAP2K1	A0A340Y5C2	A0A340WM60	Serine/threonine-protein kinase B-raf.	Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily.	0.987
BRAF	MAP2K2	A0A340Y5C2	A0A340XKD9	Serine/threonine-protein kinase B-raf.	Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.	0.986
BRAF	MAPK1	A0A340Y5C2	A0A340WNH5	Serine/threonine-protein kinase B-raf.	Mitogen-activated protein kinase 1 isoform X1.	0.855
BRAF	MAPK3	A0A340Y5C2	A0A340WYU9	Serine/threonine-protein kinase B-raf.	Mitogen-activated protein kinase.	0.854
BRAF	SPRY2	A0A340Y5C2	A0A340XZP8	Serine/threonine-protein kinase B-raf.	Protein sprouty homolog 2 isoform X1.	0.924
EDN1	AVP	A0A340WFW5	A0A340XVS1	Endothelin-1.	Vasopressin-neurophysin 2-copeptin; Belongs to the vasopressin/oxytocin family.	0.489
EDN1	FGF2	A0A340WFW5	A0A340YAR7	Endothelin-1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.636
EDN1	KDR	A0A340WFW5	A0A340WTC3	Endothelin-1.	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.530
EGF	FGF10	A0A340XVB5	A0A340XK40	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.761
EGF	FGF18	A0A340XVB5	A0A340Y1S0	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.761
EGF	FGF2	A0A340XVB5	A0A340YAR7	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.782
EGF	FGF23	A0A340XVB5	A0A340Y7E0	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.402
EGF	KDR	A0A340XVB5	A0A340WTC3	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Vascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.727
EGF	SOX9	A0A340XVB5	A0A340WYL2	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Transcription factor SOX-9 isoform X1.	0.440
EGF	SPRY1	A0A340XVB5	A0A340YCN3	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Protein sprouty homolog 1 isoform X1.	0.555
EGF	SPRY2	A0A340XVB5	A0A340XZP8	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Protein sprouty homolog 2 isoform X1.	0.500
FGF10	EGF	A0A340XK40	A0A340XVB5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.761