STRINGSTRING
FBXW7 FBXW7 BMP4 BMP4 SEMA7A SEMA7A TPBG TPBG CCL14 CCL14 PTPRC PTPRC CSF1R CSF1R LOC103070587 LOC103070587 NPTN NPTN SRC SRC FERMT2 FERMT2 RAMP3 RAMP3 CCL4 CCL4 HAVCR2 HAVCR2 TRPV4 TRPV4 BMPER BMPER RIPK2 RIPK2 CD44 CD44 CCL5 CCL5 RAPGEF2 RAPGEF2 LOC103089570 LOC103089570 CCL15 CCL15 CHI3L1 CHI3L1 MAP2K1 MAP2K1 PDGFRB PDGFRB CD74 CD74 P2RY6 P2RY6 AAED1 AAED1 PRKCZ PRKCZ HTR2C HTR2C RAP1A RAP1A CRKL CRKL FGB FGB LOC103071815 LOC103071815 PDGFD PDGFD KDR KDR ACKR3 ACKR3 LOC103068503 LOC103068503 PYCARD PYCARD LOC103081295 LOC103081295 ABL1 ABL1 LOC103069631 LOC103069631 MAPK3 MAPK3 RIPK1 RIPK1 PRKCA PRKCA SLC30A10 SLC30A10 PDGFRA PDGFRA PDGFB PDGFB SERPINF2 SERPINF2 CTGF CTGF ARRB1 ARRB1 HAND2 HAND2 NODAL NODAL NOTCH2 NOTCH2 TEK TEK GLIPR2 GLIPR2 GAREM GAREM ALOX15 ALOX15 DNAJC27 DNAJC27 SHC1 SHC1 TREM2 TREM2 CCL11 CCL11 CCL2 CCL2 OPRM1 OPRM1 CARD9 CARD9 ADCYAP1 ADCYAP1 ARRB2 ARRB2 PLA2G5 PLA2G5 AGER AGER ST5 ST5 TNFRSF11A TNFRSF11A C5AR1 C5AR1 RASGRP1 RASGRP1 XCL1 XCL1 LOC103075456 LOC103075456 CCL25 CCL25 CXCL17 CXCL17 C5AR2 C5AR2 TGFB1 TGFB1 PRKD2 PRKD2 NOTCH1 NOTCH1 F2RL1 F2RL1 NOD2 NOD2 FGF10 FGF10 PRKCDBP PRKCDBP PTPN22 PTPN22 JUN JUN HTR2B HTR2B F2R F2R EGFR EGFR NOX4 NOX4 FAM150A FAM150A PDGFC PDGFC GPR55 GPR55 FGFR4 FGFR4 FGF21 FGF21 IL26 IL26 NOD1 NOD1 LOC103081170 LOC103081170 LOC103073993 LOC103073993 GAS6 GAS6 PTK2B PTK2B LOC103088938 LOC103088938 HTR2A HTR2A GCG GCG APP APP SCIMP SCIMP SPRY2 SPRY2 GPER1 GPER1 FGF4 FGF4 LOC103088679 LOC103088679 FLT4 FLT4 PDGFA PDGFA PHB PHB SLAMF1 SLAMF1 FGF18 FGF18 LOC103089209 LOC103089209 FGFR3 FGFR3 HRAS HRAS LOC103088671 LOC103088671 CX3CL1 CX3CL1 LOC103080261 LOC103080261 BRAF BRAF CCL24 CCL24 CCL26 CCL26 NDRG4 NDRG4 FBXW9 FBXW9 TNFSF11 TNFSF11 HCRTR1 HCRTR1 FGF2 FGF2 PTPN11 PTPN11 BMP2 BMP2 PDE8A PDE8A GAREML GAREML FGF8 FGF8 DSTYK DSTYK FFAR4 FFAR4 CCL21 CCL21 CIB1 CIB1 CCL19 CCL19 CCL3 CCL3 THPO THPO FGF1 FGF1 FAM150B FAM150B FGF23 FGF23 CCL22 CCL22 PHB2 PHB2 ERBB4 ERBB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FBXW7F-box/WD repeat-containing protein 7 isoform X1. (707 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
SEMA7Asemaphorin-7A isoform X1; Belongs to the semaphorin family. (663 aa)
TPBGTrophoblast glycoprotein. (419 aa)
CCL14LOW QUALITY PROTEIN: c-C motif chemokine 14. (101 aa)
PTPRCReceptor-type tyrosine-protein phosphatase C. (1121 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (456 aa)
LOC103070587Tyrosine-protein kinase ABL1-like. (126 aa)
NPTNNeuroplastin isoform X1. (398 aa)
SRCTyrosine-protein kinase. (548 aa)
FERMT2Fermitin family homolog 2 isoform X1. (687 aa)
RAMP3Receptor activity-modifying protein 3. (147 aa)
CCL4C-C motif chemokine. (92 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (280 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (863 aa)
BMPERBMP-binding endothelial regulator protein isoform X1. (685 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
CD44CD44 antigen isoform X1. (745 aa)
CCL5C-C motif chemokine. (91 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1483 aa)
LOC103089570C-C motif chemokine. (90 aa)
CCL15C-C motif chemokine. (126 aa)
CHI3L1LOW QUALITY PROTEIN: chitinase-3-like protein 1; Belongs to the glycosyl hydrolase 18 family. (383 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1 isoform X1; Belongs to the protein kinase superfamily. (393 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
CD74HLA class II histocompatibility antigen gamma chain. (278 aa)
P2RY6P2Y purinoceptor 6. (328 aa)
AAED1Thioredoxin-like protein AAED1. (234 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
HTR2C5-hydroxytryptamine receptor 2C. (458 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
CRKLCrk-like protein. (303 aa)
FGBFibrinogen beta chain isoform X1. (488 aa)
LOC103071815Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
PDGFDPlatelet-derived growth factor D-like isoform X1. (370 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
LOC103068503LOW QUALITY PROTEIN: fibrinogen gamma-B chain-like. (445 aa)
PYCARDApoptosis-associated speck-like protein containing a CARD isoform X1. (195 aa)
LOC103081295C-C motif chemokine. (97 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
LOC103069631c-C motif chemokine 1-like. (93 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (523 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
SLC30A10Zinc transporter 10. (485 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
SERPINF2Alpha-2-antiplasmin isoform X1; Belongs to the serpin family. (494 aa)
CTGFConnective tissue growth factor. (349 aa)
ARRB1Beta-arrestin-1. (418 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (165 aa)
NODALNodal homolog. (349 aa)
NOTCH2Neurogenic locus notch homolog protein 2-like. (2471 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
GLIPR2Golgi-associated plant pathogenesis-related protein 1 isoform X1; Belongs to the CRISP family. (154 aa)
GAREMGRB2-associated and regulator of MAPK protein isoform X1. (876 aa)
ALOX15LOW QUALITY PROTEIN: arachidonate 15-lipoxygenase. (663 aa)
DNAJC27dnaJ homolog subfamily C member 27 isoform X1. (273 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
CCL11C-C motif chemokine. (99 aa)
CCL2C-C motif chemokine. (99 aa)
OPRM1Mu-type opioid receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (479 aa)
CARD9Caspase recruitment domain-containing protein 9. (539 aa)
ADCYAP1Pituitary adenylate cyclase-activating polypeptide isoform X1. (176 aa)
ARRB2Beta-arrestin-2 isoform X1. (421 aa)
PLA2G5Phospholipase A(2). (138 aa)
AGERAdvanced glycosylation end product-specific receptor isoform X1. (421 aa)
ST5Suppression of tumorigenicity 5 protein isoform X1. (1138 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A. (850 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X1. (797 aa)
XCL1Lymphotactin. (112 aa)
LOC103075456c-C motif chemokine 8-like. (99 aa)
CCL25c-C motif chemokine 25. (151 aa)
CXCL17VEGF coregulated chemokine 1. (119 aa)
C5AR2C5a anaphylatoxin chemotactic receptor 2. (337 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (391 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (852 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2536 aa)
F2RL1Proteinase-activated receptor 2. (397 aa)
NOD2Nucleotide-binding oligomerization domain-containing protein 2. (1013 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
PRKCDBPProtein kinase C delta-binding protein. (262 aa)
PTPN22Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (808 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (337 aa)
HTR2B5-hydroxytryptamine receptor 2B. (537 aa)
F2RProteinase-activated receptor 1; Belongs to the G-protein coupled receptor 1 family. (428 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
NOX4NADPH oxidase 4 isoform X1. (578 aa)
FAM150AProtein FAM150A. (131 aa)
PDGFCPlatelet-derived growth factor C. (345 aa)
GPR55G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (341 aa)
FGFR4Fibroblast growth factor receptor. (800 aa)
FGF21Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
IL26Interleukin-26. (170 aa)
NOD1Nucleotide-binding oligomerization domain-containing protein 1. (953 aa)
LOC103081170Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (465 aa)
LOC103073993Apoptosis-associated speck-like protein containing a CARD-like. (258 aa)
GAS6Growth arrest-specific protein 6. (540 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
LOC103088938N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform A-like. (313 aa)
HTR2A5-hydroxytryptamine receptor 2A. (469 aa)
GCGGlucagon isoform X1. (180 aa)
APPAmyloid beta A4 protein isoform X1. (767 aa)
SCIMPSLP adapter and CSK-interacting membrane protein. (143 aa)
SPRY2Protein sprouty homolog 2 isoform X1. (315 aa)
GPER1G-protein coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
LOC103088679G-protein coupled receptor 183-like; Belongs to the G-protein coupled receptor 1 family. (360 aa)
FLT4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1594 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
PHBProhibitin. (297 aa)
SLAMF1Signaling lymphocytic activation molecule. (339 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC103089209N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform B-like. (321 aa)
FGFR3Fibroblast growth factor receptor. (804 aa)
HRASGTPase HRas isoform X1. (189 aa)
LOC103088671N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform C-like. (333 aa)
CX3CL1Fractalkine. (388 aa)
LOC103080261C-C motif chemokine. (201 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
CCL24c-C motif chemokine 24. (130 aa)
CCL26c-C motif chemokine 26. (94 aa)
NDRG4Protein NDRG4-A isoform X1. (431 aa)
FBXW9F-box/WD repeat-containing protein 9. (458 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
HCRTR1Orexin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (425 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
PDE8APhosphodiesterase. (837 aa)
GAREMLLOW QUALITY PROTEIN: GRB2-associated and regulator of MAPK protein-like. (898 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
DSTYKDual serine/threonine and tyrosine protein kinase isoform X1. (929 aa)
FFAR4Free fatty acid receptor 4 isoform X1. (360 aa)
CCL21c-C motif chemokine 21. (131 aa)
CIB1Calcium and integrin-binding protein 1. (191 aa)
CCL19C-C motif chemokine. (100 aa)
CCL3LOW QUALITY PROTEIN: chemokine (C-C motif) ligand 3. (88 aa)
THPOThrombopoietin isoform X1. (319 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa)
FAM150BProtein FAM150B. (152 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (244 aa)
CCL22C-C motif chemokine. (93 aa)
PHB2Prohibitin. (299 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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