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RAPGEF2 RAPGEF2 KCNE1 KCNE1 SLC26A6 SLC26A6 ITPR2 ITPR2 LOC103085837 LOC103085837 PDE2A PDE2A CFTR CFTR RAP1A RAP1A DMTN DMTN AQP8 AQP8 PKD2 PKD2 AKAP6 AKAP6 GPD1 GPD1 LOC103090748 LOC103090748 WNT10B WNT10B PIK3CG PIK3CG SLC26A3 SLC26A3 INPP5K INPP5K ZFP36L1 ZFP36L1 AQP9 AQP9 HCN3 HCN3 IGFBP5 IGFBP5 WT1 WT1 HCN2 HCN2 SLC5A5 SLC5A5 RAP1B RAP1B AKAP9 AKAP9 EZR EZR AHR AHR RAPGEF3 RAPGEF3 KCNQ1 KCNQ1 AQP1 AQP1 HCN1 HCN1 LOC103088976 LOC103088976 CRHBP CRHBP FDX1 FDX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAPGEF2Rap guanine nucleotide exchange factor 2. (1483 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (129 aa)
SLC26A6Solute carrier family 26 member 6. (761 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
LOC103085837Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4-like. (1200 aa)
PDE2APhosphodiesterase. (941 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
RAP1ARas-related protein Rap-1A. (184 aa)
DMTNDematin isoform X1. (405 aa)
AQP8Aquaporin-8; Belongs to the MIP/aquaporin (TC 1.A.8) family. (263 aa)
PKD2LOW QUALITY PROTEIN: polycystin-2. (963 aa)
AKAP6A-kinase anchor protein 6. (2320 aa)
GPD1Glycerol-3-phosphate dehydrogenase [NAD(+)]. (349 aa)
LOC103090748Zinc finger protein 36, C3H1 type-like 1-like. (226 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
PIK3CGLOW QUALITY PROTEIN: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1126 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (759 aa)
INPP5KInositol polyphosphate 5-phosphatase K isoform X1. (450 aa)
ZFP36L1Zinc finger protein 36, C3H1 type-like 1-like. (338 aa)
AQP9Aquaporin-9; Belongs to the MIP/aquaporin (TC 1.A.8) family. (295 aa)
HCN3Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3. (786 aa)
IGFBP5Insulin-like growth factor-binding protein 5. (271 aa)
WT1Wilms tumor protein isoform X1. (450 aa)
HCN2LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2. (904 aa)
SLC5A5Sodium/iodide cotransporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (642 aa)
RAP1BRas-related protein Rap-1b isoform X1. (184 aa)
AKAP9A-kinase anchor protein 9. (3874 aa)
EZREzrin isoform X1. (586 aa)
AHRLOW QUALITY PROTEIN: aryl hydrocarbon receptor. (847 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (923 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (580 aa)
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
HCN1Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (876 aa)
LOC103088976Ras-related protein Rap-1b-like isoform X1. (165 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
FDX1Adrenodoxin, mitochondrial. (193 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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