Groups of genes that are frequently observed in each other's genomic neighborhood.
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Experiments
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Coexpression
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103083323
Periaxin-like. (147 aa)
EMILIN1
EMILIN-1. (1015 aa)
EMILIN2
EMILIN-2. (1070 aa)
AHNAK2
Protein AHNAK2. (3569 aa)
LOC103083050
Periaxin-like. (1142 aa)
AHNAK
Neuroblast differentiation-associated protein AHNAK. (5683 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797 Other names: L. vexillifer, Yangtze River dolphin, baiji