STRINGSTRING
WNK1 WNK1 KCNIP3 KCNIP3 KCNIP2 KCNIP2 SCN1B SCN1B BSND BSND FXYD3 FXYD3 FXYD5 FXYD5 PCSK9 PCSK9 NEDD4 NEDD4 WNK3 WNK3 GRM3 GRM3 KCNE3 KCNE3 ADRB2 ADRB2 KCNE1 KCNE1 AMIGO3 AMIGO3 KCNMB1 KCNMB1 KCNE2 KCNE2 STOML1 STOML1 CACNG2 CACNG2 SGK3 SGK3 SNTA1 SNTA1 REM1 REM1 REM2 REM2 VTI1B VTI1B CABP1 CABP1 CABP2 CABP2 NRXN3 NRXN3 WNK4 WNK4 CFTR CFTR PRKCB PRKCB LOC103077771 LOC103077771 AMIGO1 AMIGO1 STIM2 STIM2 LOC103073106 LOC103073106 CRISP2 CRISP2 LOC103083838 LOC103083838 PTPN3 PTPN3 CACNB3 CACNB3 CABP4 CABP4 CNTD1 CNTD1 NEDD4L NEDD4L PRSS8 PRSS8 SLC30A1 SLC30A1 KCNAB2 KCNAB2 CAV1 CAV1 YWHAH YWHAH TMEM110 TMEM110 LOC103091465 LOC103091465 HPCAL4 HPCAL4 KCNMB2 KCNMB2 LOC103081481 LOC103081481 YWHAE YWHAE GRM2 GRM2 TMPRSS3 TMPRSS3 GEM GEM ITPR1 ITPR1 CACNG1 CACNG1 GPLD1 GPLD1 STX7 STX7 SLC9A3R1 SLC9A3R1 FKBP1B FKBP1B RRAD RRAD LRRC52 LRRC52 LOC103083779 LOC103083779 KCNAB3 KCNAB3 CACNG5 CACNG5 STX8 STX8 RANGRF RANGRF LRRC55 LRRC55 PDZD4 PDZD4 PACSIN3 PACSIN3 DPP6 DPP6 SCN2B SCN2B FXYD6 FXYD6 SCN4B SCN4B CACNG7 CACNG7 LRRC26 LRRC26 CACNG6 CACNG6 SCLT1 SCLT1 FLNA FLNA KCNAB1 KCNAB1 LOC103076006 LOC103076006 PHPT1 PHPT1 LOC103084703 LOC103084703 SCN3B SCN3B STIM1 STIM1 TSPAN13 TSPAN13 CCDC109B CCDC109B FGF14 FGF14 AMIGO2 AMIGO2 LOC103087767 LOC103087767 AKAP9 AKAP9 LRRC38 LRRC38 KCNE4 KCNE4 KCNIP4 KCNIP4 KCNS1 KCNS1 COMMD1 COMMD1 CABP5 CABP5 KCNMB4 KCNMB4 KCNE1L KCNE1L CAV3 CAV3 SGK2 SGK2 LYNX1 LYNX1 KCNIP1 KCNIP1 DLG1 DLG1 WNK2 WNK2 STX1A STX1A VAMP5 VAMP5 FGF12 FGF12 LOC103072080 LOC103072080 PRKG1 PRKG1 FXYD1 FXYD1 VAMP8 VAMP8 FXYD7 FXYD7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNK1Serine/threonine-protein kinase WNK1 isoform X1. (2636 aa)
KCNIP3Calsenilin isoform X1. (255 aa)
KCNIP2Kv channel-interacting protein 2 isoform X1. (285 aa)
SCN1BSodium channel subunit beta-1. (218 aa)
BSNDBarttin isoform X2. (313 aa)
FXYD3FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (88 aa)
FXYD5FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (172 aa)
PCSK9LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 9. (659 aa)
NEDD4E3 ubiquitin-protein ligase. (782 aa)
WNK3Serine/threonine-protein kinase WNK3 isoform X1. (1800 aa)
GRM3Metabotropic glutamate receptor 3 isoform X1. (879 aa)
KCNE3Potassium voltage-gated channel subfamily E member 3. (99 aa)
ADRB2Beta-2 adrenergic receptor. (419 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (129 aa)
AMIGO3Amphoterin-induced protein 3. (510 aa)
KCNMB1Calcium-activated potassium channel subunit beta-1. (195 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2. (123 aa)
STOML1Stomatin-like protein 1 isoform X1. (398 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa)
SNTA1Alpha-1-syntrophin isoform X1. (505 aa)
REM1GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (298 aa)
REM2GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (340 aa)
VTI1BVesicle transport through interaction with t-SNAREs homolog 1B. (232 aa)
CABP1Calcium-binding protein 1 isoform X1. (368 aa)
CABP2Calcium-binding protein 2 isoform X1. (168 aa)
NRXN3Neurexin-3-like. (1131 aa)
WNK4Serine/threonine-protein kinase WNK4. (1232 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
LOC103077771E3 ubiquitin-protein ligase NEDD4-like. (515 aa)
AMIGO1Amphoterin-induced protein 1 isoform X1. (493 aa)
STIM2Stromal interaction molecule 2 isoform X1. (838 aa)
LOC103073106Uncharacterized protein LOC103073106. (173 aa)
CRISP2Cysteine-rich secretory protein 2; Belongs to the CRISP family. (244 aa)
LOC103083838Neurexin-3-beta-like isoform X1. (397 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (915 aa)
CACNB3Voltage-dependent L-type calcium channel subunit beta-3 isoform X1. (484 aa)
CABP4Calcium-binding protein 4. (272 aa)
CNTD1Cyclin N-terminal domain-containing protein 1. (337 aa)
NEDD4LE3 ubiquitin-protein ligase. (854 aa)
PRSS8Prostasin isoform X1; Belongs to the peptidase S1 family. (344 aa)
SLC30A1Zinc transporter 1. (504 aa)
KCNAB2Voltage-gated potassium channel subunit beta-2 isoform X1. (415 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
TMEM110Transmembrane protein 110. (294 aa)
LOC103091465Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
HPCAL4Hippocalcin-like protein 4 isoform X1. (191 aa)
KCNMB2Calcium-activated potassium channel subunit beta-2. (235 aa)
LOC103081481LOW QUALITY PROTEIN: cysteine-rich secretory protein 1-like; Belongs to the CRISP family. (253 aa)
YWHAE14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
GRM2Metabotropic glutamate receptor 2. (872 aa)
TMPRSS3Transmembrane protease serine 3 isoform X1; Belongs to the peptidase S1 family. (476 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (311 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (224 aa)
GPLD1Phosphatidylinositol-glycan-specific phospholipase D isoform X1. (839 aa)
STX7Syntaxin-7; Belongs to the syntaxin family. (261 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (365 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
LRRC52Leucine-rich repeat-containing protein 52. (315 aa)
LOC103083779Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (261 aa)
KCNAB3Voltage-gated potassium channel subunit beta-3 isoform X1. (404 aa)
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
STX8Syntaxin-8. (260 aa)
RANGRFRan guanine nucleotide release factor isoform X2. (186 aa)
LRRC55Leucine-rich repeat-containing protein 55. (318 aa)
PDZD4PDZ domain-containing protein 4 isoform X1. (776 aa)
PACSIN3Protein kinase C and casein kinase substrate in neurons protein 3 isoform X1. (424 aa)
DPP6Dipeptidyl aminopeptidase-like protein 6 isoform X1; Belongs to the peptidase S9B family. (871 aa)
SCN2BSodium channel subunit beta-2. (215 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (143 aa)
SCN4BSodium channel subunit beta-4. (228 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
LRRC26Leucine-rich repeat-containing protein 26. (417 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit. (225 aa)
SCLT1Sodium channel and clathrin linker 1. (665 aa)
FLNAfilamin-A isoform X1. (2647 aa)
KCNAB1Voltage-gated potassium channel subunit beta-1 isoform X1. (419 aa)
LOC103076006Fibroblast growth factor 11-like; Belongs to the heparin-binding growth factors family. (174 aa)
PHPT114 kDa phosphohistidine phosphatase isoform X2. (127 aa)
LOC103084703Neuronal acetylcholine receptor subunit alpha-7-like. (499 aa)
SCN3BSodium channel subunit beta-3 isoform X1. (255 aa)
STIM1Stromal interaction molecule 1 isoform X1. (785 aa)
TSPAN13Tetraspanin-13; Belongs to the tetraspanin (TM4SF) family. (204 aa)
CCDC109BLOW QUALITY PROTEIN: mitochondrial calcium uniporter regulatory subunit MCUb. (334 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
AMIGO2Amphoterin-induced protein 2 isoform X1. (521 aa)
LOC103087767Voltage-dependent calcium channel gamma-6 subunit-like. (85 aa)
AKAP9A-kinase anchor protein 9. (3874 aa)
LRRC38Leucine-rich repeat-containing protein 38. (440 aa)
KCNE4Potassium voltage-gated channel subfamily E member 4. (170 aa)
KCNIP4Kv channel-interacting protein 4 isoform X1. (233 aa)
KCNS1Potassium voltage-gated channel subfamily S member 1; Belongs to the potassium channel family. (545 aa)
COMMD1COMM domain-containing protein 1. (188 aa)
CABP5Calcium-binding protein 5 isoform X1. (173 aa)
KCNMB4Calcium-activated potassium channel subunit beta-4. (210 aa)
KCNE1LPotassium voltage-gated channel subfamily E member 1-like protein. (145 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)
LYNX1Ly-6/neurotoxin-like protein 1. (114 aa)
KCNIP1Kv channel-interacting protein 1 isoform X2. (213 aa)
DLG1Disks large homolog 1 isoform X1; Belongs to the MAGUK family. (927 aa)
WNK2Serine/threonine-protein kinase WNK2. (2234 aa)
STX1Asyntaxin-1A; Belongs to the syntaxin family. (288 aa)
VAMP5Vesicle-associated membrane protein 5. (111 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
LOC103072080Small ubiquitin-related modifier. (106 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (104 aa)
VAMP8Vesicle-associated membrane protein 8. (99 aa)
FXYD7FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (80 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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