STRINGSTRING
MAP3K4 MAP3K4 MAP3K3 MAP3K3 HAND2 HAND2 ZC3H12A ZC3H12A GDF6 GDF6 SPHK1 SPHK1 STK39 STK39 SASH1 SASH1 RELL1 RELL1 BMP4 BMP4 BMP2 BMP2 LEP LEP RELL2 RELL2 EMC10 EMC10 PJA2 PJA2 GADD45A GADD45A GADD45B GADD45B AGER AGER XDH XDH NCF1 NCF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1644 aa)
MAP3K3Mitogen-activated protein kinase kinase kinase 3. (647 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (165 aa)
ZC3H12ARibonuclease ZC3H12A. (583 aa)
GDF6Growth/differentiation factor 6. (461 aa)
SPHK1Sphingosine kinase 1. (484 aa)
STK39STE20/SPS1-related proline-alanine-rich protein kinase. (659 aa)
SASH1SAM and SH3 domain-containing protein 1. (1235 aa)
RELL1RELT-like protein 1. (270 aa)
BMP4Bone morphogenetic protein 4 isoform X1. (420 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
RELL2RELT-like protein 2. (303 aa)
EMC10ER membrane protein complex subunit 10 isoform X1. (260 aa)
PJA2E3 ubiquitin-protein ligase Praja-2. (709 aa)
GADD45AGrowth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa)
GADD45BGrowth arrest and DNA damage-inducible protein GADD45 beta. (160 aa)
AGERAdvanced glycosylation end product-specific receptor isoform X1. (421 aa)
XDHXanthine dehydrogenase/oxidase isoform X1. (1334 aa)
NCF1Neutrophil cytosol factor 1. (393 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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