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INPP5D INPP5D STAT2 STAT2 SH2D7 SH2D7 BTK BTK PTPN11 PTPN11 LCK LCK SH2B2 SH2B2 ZAP70 ZAP70 PTPN6 PTPN6 SH2D6 SH2D6 SHE SHE BLK BLK FES FES SH2D3C SH2D3C SH3BP2 SH3BP2 STAP1 STAP1 SOCS2 SOCS2 BMX BMX BCAR3 BCAR3 SHF SHF SOCS7 SOCS7 SH2B3 SH2B3 TNS1 TNS1 ABL1 ABL1 CHN1 CHN1 TXK TXK VAV2 VAV2 JAK2 JAK2 PIK3R3 PIK3R3 FYN FYN CISH CISH CRKL CRKL ABL2 ABL2 TEC TEC VAV3 VAV3 RASA1 RASA1 GRB14 GRB14 SLA SLA SLA2 SLA2 STAT3 STAT3 ITK ITK STAT5A STAT5A TENC1 TENC1 CSK CSK GRAP GRAP GRB10 GRB10 STAT5B STAT5B SOCS4 SOCS4 LCP2 LCP2 SRC SRC SYK SYK HCK HCK SHC3 SHC3 STAT6 STAT6 LOC103069777 LOC103069777 LOC103069117 LOC103069117 DAPP1 DAPP1 TNS4 TNS4 GRB7 GRB7 LYN LYN SOCS1 SOCS1 INPPL1 INPPL1 STAT4 STAT4 PLCG1 PLCG1 TNS3 TNS3 SOCS6 SOCS6 RIN1 RIN1 HSH2D HSH2D VAV1 VAV1 TYK2 TYK2 SH2D3A SH2D3A SHD SHD MATK MATK FER FER JAK1 JAK1 SOCS3 SOCS3 PIK3R2 PIK3R2 JAK3 JAK3 SHC2 SHC2 FGR FGR STAP2 STAP2 YES1 YES1 SH2D2A SH2D2A SOCS5 SOCS5 SH2D1B SH2D1B SH2D5 SH2D5 NCK1 NCK1 SHC1 SHC1 SHB SHB PIK3R1 PIK3R1 NCK2 NCK2 GRB2 GRB2 GRAP2 GRAP2 RIN3 RIN3 BLNK BLNK RIN2 RIN2 SHC4 SHC4 SH2D4A SH2D4A SH2D1A SH2D1A SH2B1 SH2B1 FRK FRK SUPT6H SUPT6H CRK CRK PLCG2 PLCG2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1187 aa)
STAT2Signal transducer and activator of transcription. (895 aa)
SH2D7LOW QUALITY PROTEIN: SH2 domain-containing protein 7. (454 aa)
BTKTyrosine-protein kinase. (659 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
LCKTyrosine-protein kinase. (520 aa)
SH2B2SH2B adapter protein 2. (660 aa)
ZAP70Tyrosine-protein kinase. (635 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
SH2D6SH2 domain-containing protein 6. (233 aa)
SHELOW QUALITY PROTEIN: Src homology 2 domain containing E. (519 aa)
BLKTyrosine-protein kinase. (501 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
SH2D3CSH2 domain-containing protein 3C isoform X1. (856 aa)
SH3BP2SH3 domain-binding protein 2 isoform X1. (594 aa)
STAP1LOW QUALITY PROTEIN: signal transducing adaptor family member 1. (231 aa)
SOCS2Suppressor of cytokine signaling 2 isoform X1. (198 aa)
BMXTyrosine-protein kinase. (651 aa)
BCAR3Breast cancer anti-estrogen resistance protein 3 isoform X1. (825 aa)
SHFSH2 domain-containing adapter protein F. (367 aa)
SOCS7Suppressor of cytokine signaling 7. (677 aa)
SH2B3SH2B adapter protein 3. (573 aa)
TNS1Tensin-1 isoform X1. (1895 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
CHN1Chimaerin; GTPase-activating protein for p21-rac. (459 aa)
TXKTyrosine-protein kinase. (525 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (878 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
FYNTyrosine-protein kinase. (537 aa)
CISHCytokine-inducible SH2-containing protein. (254 aa)
CRKLCrk-like protein. (303 aa)
ABL2Tyrosine-protein kinase. (1067 aa)
TECTyrosine-protein kinase. (633 aa)
VAV3Guanine nucleotide exchange factor VAV3 isoform X1. (875 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
GRB14Growth factor receptor-bound protein 14 isoform X1. (540 aa)
SLASrc-like-adapter isoform X1. (276 aa)
SLA2Src-like-adapter 2. (276 aa)
STAT3Signal transducer and activator of transcription. (654 aa)
ITKTyrosine-protein kinase. (620 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
TENC1Tensin-like C1 domain-containing phosphatase. (1371 aa)
CSKTyrosine-protein kinase. (450 aa)
GRAPGRB2-related adapter protein. (217 aa)
GRB10Growth factor receptor-bound protein 10 isoform X1. (588 aa)
STAT5BSignal transducer and activator of transcription. (792 aa)
SOCS4Suppressor of cytokine signaling 4. (440 aa)
LCP2Lymphocyte cytosolic protein 2. (532 aa)
SRCTyrosine-protein kinase. (548 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
HCKTyrosine-protein kinase. (504 aa)
SHC3SHC-transforming protein 3. (588 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
LOC103069777Beta-chimaerin-like. (345 aa)
LOC103069117LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-like. (721 aa)
DAPP1Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X1. (316 aa)
TNS4Tensin-4. (705 aa)
GRB7LOW QUALITY PROTEIN: growth factor receptor-bound protein 7. (557 aa)
LYNTyrosine-protein kinase. (516 aa)
SOCS1Suppressor of cytokine signaling 1. (216 aa)
INPPL1LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1264 aa)
STAT4Signal transducer and activator of transcription. (748 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
TNS3Tensin-3-like. (1439 aa)
SOCS6Suppressor of cytokine signaling 6. (535 aa)
RIN1Ras and Rab interactor 1. (786 aa)
HSH2DHematopoietic SH2 domain-containing protein. (346 aa)
VAV1Proto-oncogene vav isoform X1. (844 aa)
TYK2Tyrosine-protein kinase. (1186 aa)
SH2D3ASH2 domain-containing protein 3A. (573 aa)
SHDSH2 domain-containing adapter protein D. (340 aa)
MATKTyrosine-protein kinase. (485 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
SHC2SHC-transforming protein 2. (801 aa)
FGRTyrosine-protein kinase. (537 aa)
STAP2Signal-transducing adaptor protein 2. (411 aa)
YES1Tyrosine-protein kinase. (541 aa)
SH2D2ASH2 domain-containing protein 2A isoform X1. (406 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
SH2D1BLOW QUALITY PROTEIN: SH2 domain-containing protein 1B. (133 aa)
SH2D5SH2 domain-containing protein 5 isoform X1. (429 aa)
NCK1Cytoplasmic protein. (377 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
SHBLOW QUALITY PROTEIN: SH2 domain-containing adapter protein B. (595 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
NCK2Cytoplasmic protein. (376 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
GRAP2GRB2-related adapter protein 2. (317 aa)
RIN3Ras and Rab interactor 3. (1022 aa)
BLNKB-cell linker protein isoform X1. (459 aa)
RIN2LOW QUALITY PROTEIN: ras and Rab interactor 2. (940 aa)
SHC4SHC-transforming protein 4 isoform X1. (631 aa)
SH2D4ASH2 domain-containing protein 4A. (389 aa)
SH2D1ASH2 domain-containing protein 1A; Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. (128 aa)
SH2B1SH2B adapter protein 1 isoform X1. (760 aa)
FRKTyrosine-protein kinase. (513 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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