STRINGSTRING
DDR1 DDR1 CSF1R CSF1R ACVR1C ACVR1C HCK HCK SYK SYK SRC SRC TNNI3K TNNI3K NTRK3 NTRK3 LOC103090862 LOC103090862 CSK CSK LMTK2 LMTK2 RIPK2 RIPK2 ACVR1 ACVR1 TEX14 TEX14 EPHA5 EPHA5 ITK ITK PDGFRB PDGFRB MUSK MUSK MET MET TEC TEC ABL2 ABL2 RET RET LOC103070587 LOC103070587 RIPK3 RIPK3 FLT1 FLT1 FES FES BLK BLK NRBP1 NRBP1 MERTK MERTK FLT3 FLT3 DSTYK DSTYK ALK ALK MAP3K9 MAP3K9 ZAP70 ZAP70 EPHB3 EPHB3 STYK1 STYK1 FGFR1 FGFR1 LCK LCK LOC103069064 LOC103069064 FGFR2 FGFR2 BTK BTK IGF1R IGF1R EPHB4 EPHB4 ERBB4 ERBB4 ERBB3 ERBB3 BRAF BRAF LIMK1 LIMK1 TIE1 TIE1 EPHB6 EPHB6 EPHA3 EPHA3 BMX BMX TNK2 TNK2 FGFR3 FGFR3 EPHA4 EPHA4 FLT4 FLT4 LOC103089656 LOC103089656 EPHA1 EPHA1 PTK2 PTK2 MST1R MST1R PTK2B PTK2B LYN LYN ERBB2 ERBB2 FGFR4 FGFR4 EPHA7 EPHA7 BMPR1B BMPR1B MAP3K11 MAP3K11 EGFR EGFR GUCY2F GUCY2F RAF1 RAF1 LMTK3 LMTK3 MLKL MLKL TYK2 TYK2 MATK MATK LTK LTK FER FER JAK1 JAK1 AATK AATK JAK3 JAK3 EPHA6 EPHA6 EPHA2 EPHA2 FGR FGR TYRO3 TYRO3 ROR1 ROR1 EPHA8 EPHA8 EPHB2 EPHB2 ILK ILK LOC103079692 LOC103079692 MAP3K10 MAP3K10 AXL AXL INSR INSR NPR1 NPR1 YES1 YES1 INSRR INSRR TNK1 TNK1 PTK7 PTK7 GUCY2D GUCY2D RYK RYK KIT KIT ROR2 ROR2 BMPR1A BMPR1A TGFBR2 TGFBR2 NTRK1 NTRK1 EPHB1 EPHB1 TEK TEK DDR2 DDR2 ROS1 ROS1 POMK POMK GUCY2C GUCY2C NPR2 NPR2 TESK1 TESK1 NTRK2 NTRK2 EPHA10 EPHA10 PDGFRA PDGFRA KSR2 KSR2 FRK FRK LIMK2 LIMK2 ANKK1 ANKK1 RIPK1 RIPK1 MAP3K7 MAP3K7 KSR1 KSR1 MAP3K13 MAP3K13 ABL1 ABL1 TXK TXK TESK2 TESK2 JAK2 JAK2 ACVRL1 ACVRL1 NEK6 NEK6 ARAF ARAF KDR KDR FYN FYN NEK7 NEK7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DDR1Tyrosine-protein kinase receptor. (923 aa)
CSF1RMacrophage colony-stimulating factor 1 receptor-like; Belongs to the protein kinase superfamily. Tyr protein kinase family. (456 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
HCKTyrosine-protein kinase. (504 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
SRCTyrosine-protein kinase. (548 aa)
TNNI3KSerine/threonine-protein kinase TNNI3K. (654 aa)
NTRK3Tyrosine-protein kinase receptor. (839 aa)
LOC103090862Tyrosine-protein kinase SgK223-like. (1408 aa)
CSKTyrosine-protein kinase. (450 aa)
LMTK2Serine/threonine-protein kinase LMTK2. (1498 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
TEX14Inactive serine/threonine-protein kinase TEX14. (1489 aa)
EPHA5Ephrin type-A receptor 5-like isoform X1. (1037 aa)
ITKTyrosine-protein kinase. (620 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
MUSKMuscle, skeletal receptor tyrosine-protein kinase isoform X1. (879 aa)
METHepatocyte growth factor receptor isoform X1. (1412 aa)
TECTyrosine-protein kinase. (633 aa)
ABL2Tyrosine-protein kinase. (1067 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1026 aa)
LOC103070587Tyrosine-protein kinase ABL1-like. (126 aa)
RIPK3LOW QUALITY PROTEIN: receptor-interacting serine-threonine kinase 3. (396 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
BLKTyrosine-protein kinase. (501 aa)
NRBP1Nuclear receptor-binding protein. (535 aa)
MERTKTyrosine-protein kinase Mer. (999 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
DSTYKDual serine/threonine and tyrosine protein kinase isoform X1. (929 aa)
ALKTyrosine-protein kinase receptor. (1619 aa)
MAP3K9Mitogen-activated protein kinase kinase kinase 9 isoform X1. (1125 aa)
ZAP70Tyrosine-protein kinase. (635 aa)
EPHB3Ephrin type-B receptor 3. (1005 aa)
STYK1Tyrosine-protein kinase STYK1. (427 aa)
FGFR1Fibroblast growth factor receptor. (837 aa)
LCKTyrosine-protein kinase. (520 aa)
LOC103069064Guanylate cyclase. (1015 aa)
FGFR2Fibroblast growth factor receptor. (839 aa)
BTKTyrosine-protein kinase. (659 aa)
IGF1RTyrosine-protein kinase receptor. (1367 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1338 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
LIMK1LIM domain kinase 1. (647 aa)
TIE1Tyrosine-protein kinase receptor Tie-1 isoform X1. (1139 aa)
EPHB6Ephrin type-B receptor 6. (1011 aa)
EPHA3Ephrin type-A receptor 3-like isoform X1. (984 aa)
BMXTyrosine-protein kinase. (651 aa)
TNK2Activated CDC42 kinase 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1086 aa)
FGFR3Fibroblast growth factor receptor. (804 aa)
EPHA4Ephrin type-A receptor 4-like isoform X1. (986 aa)
FLT4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1594 aa)
LOC103089656Mitogen-activated protein kinase kinase kinase. (1017 aa)
EPHA1Ephrin type-A receptor 1. (981 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1003 aa)
MST1RMacrophage-stimulating protein receptor. (1382 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
LYNTyrosine-protein kinase. (516 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
FGFR4Fibroblast growth factor receptor. (800 aa)
EPHA7Ephrin type-A receptor 7-like isoform X1. (998 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (858 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
GUCY2FGuanylate cyclase. (1144 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase isoform X1. (648 aa)
LMTK3LOW QUALITY PROTEIN: serine/threonine-protein kinase LMTK3. (1560 aa)
MLKLLOW QUALITY PROTEIN: mixed lineage kinase domain-like protein. (428 aa)
TYK2Tyrosine-protein kinase. (1186 aa)
MATKTyrosine-protein kinase. (485 aa)
LTKLOW QUALITY PROTEIN: leukocyte tyrosine kinase receptor. (858 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
AATKSerine/threonine-protein kinase LMTK1. (1333 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
EPHA6Ephrin type-A receptor 6. (1129 aa)
EPHA2Ephrin type-A receptor 2. (975 aa)
FGRTyrosine-protein kinase. (537 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (813 aa)
ROR1Tyrosine-protein kinase transmembrane receptor ROR1-like. (749 aa)
EPHA8Ephrin type-A receptor 8. (979 aa)
EPHB2Ephrin type-B receptor 2 isoform X1. (964 aa)
ILKIntegrin-linked protein kinase isoform X1. (452 aa)
LOC103079692Mitogen-activated protein kinase kinase kinase MLT-like isoform X1. (800 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (948 aa)
AXLTyrosine-protein kinase receptor UFO isoform X1. (887 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
NPR1Guanylate cyclase. (1058 aa)
YES1Tyrosine-protein kinase. (541 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
TNK1Non-receptor tyrosine-protein kinase TNK1 isoform X2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (665 aa)
PTK7Inactive tyrosine-protein kinase 7 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
GUCY2DGuanylate cyclase. (1111 aa)
RYKTyrosine-protein kinase RYK. (475 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
ROR2Tyrosine-protein kinase transmembrane receptor ROR2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (905 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (591 aa)
NTRK1Tyrosine-protein kinase receptor. (795 aa)
EPHB1Ephrin type-B receptor 1. (984 aa)
TEKAngiopoietin-1 receptor isoform X1. (1125 aa)
DDR2Discoidin domain-containing receptor 2. (867 aa)
ROS1Tyrosine-protein kinase receptor. (2348 aa)
POMKProtein O-mannose kinase. (350 aa)
GUCY2CGuanylate cyclase. (1073 aa)
NPR2Guanylate cyclase. (1052 aa)
TESK1Dual specificity testis-specific protein kinase 1. (628 aa)
NTRK2Tyrosine-protein kinase receptor. (366 aa)
EPHA10LOW QUALITY PROTEIN: ephrin type-A receptor 10. (1007 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
KSR2Kinase suppressor of Ras 2. (949 aa)
FRKTyrosine-protein kinase. (513 aa)
LIMK2LIM domain kinase 2 isoform X1. (638 aa)
ANKK1LOW QUALITY PROTEIN: ankyrin repeat and protein kinase domain-containing protein 1. (764 aa)
RIPK1Receptor-interacting serine/threonine-protein kinase 1. (523 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
KSR1Kinase suppressor of Ras 1. (757 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (968 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
TXKTyrosine-protein kinase. (525 aa)
TESK2Dual specificity testis-specific protein kinase 2 isoform X1. (572 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
NEK6Serine/threonine-protein kinase Nek6; Belongs to the protein kinase superfamily. (313 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X2. (609 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
FYNTyrosine-protein kinase. (537 aa)
NEK7Serine/threonine-protein kinase Nek7-like; Belongs to the protein kinase superfamily. (302 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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