(59 nodes) Rossmann-like alpha/beta/alpha sandwich fold network (Lipotes vexillifer)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103086710	Argininosuccinate synthase, chloroplastic-like. (405 aa)
	TRMU	LOW QUALITY PROTEIN: tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase. (449 aa)
	CTU1	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. (347 aa)
	PAPSS2	Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2. (631 aa)
	PAPSS1	LOW QUALITY PROTEIN: 3'-phosphoadenosine 5'-phosphosulfate synthase 1. (626 aa)
	CTU2	Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Belongs to the CTU2/NCS2 family. (503 aa)
	LOC103076784	Glucose-6-phosphate isomerase; Belongs to the GPI family. (821 aa)
	MARS	methionine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (900 aa)
	YARS	Tyrosine--tRNA ligase. (528 aa)
	RARS2	Probable arginine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (578 aa)
	IARS	isoleucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (1262 aa)
	CARS	cysteine--tRNA ligase, cytoplasmic isoform X2. (832 aa)
	MARS2	methionine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (593 aa)
	NADSYN1	Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (706 aa)
	ASNSD1	Asparagine synthetase domain-containing protein 1. (644 aa)
	LARS2	Probable leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (903 aa)
	PCYT1B	Choline-phosphate cytidylyltransferase B. (425 aa)
	PCYT1A	Choline-phosphate cytidylyltransferase A. (367 aa)
	LOC103090855	Deoxyribodipyrimidine photo-lyase-like. (434 aa)
	CRY1	Cryptochrome-1. (587 aa)
	DPH6	Diphthine--ammonia ligase; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. (273 aa)
	ETFB	Electron transfer flavoprotein subunit beta. (255 aa)
	ETFA	Electron transfer flavoprotein subunit alpha, mitochondrial isoform X1. (333 aa)
	LARS	leucine--tRNA ligase, cytoplasmic isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family. (1176 aa)
	PCYT2	Ethanolamine-phosphate cytidylyltransferase isoform X1. (407 aa)
	LOC103091494	5'-adenylylsulfate reductase 2, chloroplastic-like. (244 aa)
	LOC103070928	Probable methionine--tRNA ligase-like; Belongs to the class-I aminoacyl-tRNA synthetase family. (628 aa)
	LOC103070382	Argininosuccinate synthase, chloroplastic-like. (380 aa)
	VARS	valine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1264 aa)
	GMPS	GMP synthase [glutamine-hydrolyzing]. (714 aa)
	WARS2	tryptophan--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (389 aa)
	LOC103088902	Probable glutamine--tRNA ligase-like; Belongs to the class-I aminoacyl-tRNA synthetase family. (424 aa)
	CRY2	Cryptochrome-2. (593 aa)
	WARS	tryptophan--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (476 aa)
	FLAD1	FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. (566 aa)
	LOC103088898	cysteine--tRNA ligase, mitochondrial-like. (449 aa)
	EPRS	LOW QUALITY PROTEIN: bifunctional glutamate/proline--tRNA ligase. (1519 aa)
	LOC103088548	Pantoate--beta-alanine ligase-like. (281 aa)
	IARS2	isoleucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1012 aa)
	ASS1	Argininosuccinate synthase. (412 aa)
	LOC103088097	glutamate--tRNA ligase, chloroplastic/mitochondrial-like; Belongs to the class-I aminoacyl-tRNA synthetase family. (493 aa)
	NMNAT1	Nicotinamide-nucleotide adenylyltransferase. (281 aa)
	ASNS	Asparagine synthetase [glutamine-hydrolyzing]. (561 aa)
	EARS2	Probable glutamate--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (523 aa)
	YARS2	Tyrosine--tRNA ligase. (478 aa)
	COASY	Bifunctional coenzyme A synthase. (562 aa)
	LOC103071066	Putative leucine--tRNA ligase, mitochondrial-like; Belongs to the class-I aminoacyl-tRNA synthetase family. (586 aa)
	LOC103068779	Asparagine synthetase [glutamine-hydrolyzing]-like. (580 aa)
	RARS	arginine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (660 aa)
	NMNAT2	Nicotinamide mononucleotide adenylyltransferase 2. (307 aa)
	LOC103086408	Probable cysteine--tRNA ligase-like. (436 aa)
	LOC103088860	Mitochondrial tRNA-specific 2-thiouridylase 1-like. (378 aa)
	VARS2	valine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (1062 aa)
	LOC103073437	Peptidylprolyl isomerase. (1198 aa)
	LOC103088138	Probable nicotinate phosphoribosyltransferase-like. (617 aa)
	LOC103086683	Probable glutamine--tRNA ligase-like; Belongs to the class-I aminoacyl-tRNA synthetase family. (587 aa)
	NMNAT3	Nicotinamide-nucleotide adenylyltransferase. (239 aa)
	LOC103079636	Probable methionine--tRNA ligase, cytoplasmic-like; Belongs to the class-I aminoacyl-tRNA synthetase family. (649 aa)
	QARS	LOW QUALITY PROTEIN: glutamine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (793 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASNS	ASS1	A0A340WVH0	A0A340X1L8	Asparagine synthetase [glutamine-hydrolyzing].	Argininosuccinate synthase.	0.920
ASNS	EPRS	A0A340WVH0	A0A340X885	Asparagine synthetase [glutamine-hydrolyzing].	LOW QUALITY PROTEIN: bifunctional glutamate/proline--tRNA ligase.	0.431
ASNS	IARS	A0A340WVH0	A0A340Y3I1	Asparagine synthetase [glutamine-hydrolyzing].	isoleucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.459
ASNS	LOC103068779	A0A340WVH0	A0A340WLJ1	Asparagine synthetase [glutamine-hydrolyzing].	Asparagine synthetase [glutamine-hydrolyzing]-like.	0.908
ASNS	LOC103070382	A0A340WVH0	A0A340XET4	Asparagine synthetase [glutamine-hydrolyzing].	Argininosuccinate synthase, chloroplastic-like.	0.920
ASNS	LOC103086710	A0A340WVH0	A0A340WMB9	Asparagine synthetase [glutamine-hydrolyzing].	Argininosuccinate synthase, chloroplastic-like.	0.920
ASNS	YARS	A0A340WVH0	A0A340Y6A1	Asparagine synthetase [glutamine-hydrolyzing].	Tyrosine--tRNA ligase.	0.492
ASNSD1	YARS	A0A340Y0D7	A0A340Y6A1	Asparagine synthetase domain-containing protein 1.	Tyrosine--tRNA ligase.	0.411
ASS1	ASNS	A0A340X1L8	A0A340WVH0	Argininosuccinate synthase.	Asparagine synthetase [glutamine-hydrolyzing].	0.920
ASS1	LOC103068779	A0A340X1L8	A0A340WLJ1	Argininosuccinate synthase.	Asparagine synthetase [glutamine-hydrolyzing]-like.	0.920
ASS1	LOC103070382	A0A340X1L8	A0A340XET4	Argininosuccinate synthase.	Argininosuccinate synthase, chloroplastic-like.	0.904
ASS1	LOC103086710	A0A340X1L8	A0A340WMB9	Argininosuccinate synthase.	Argininosuccinate synthase, chloroplastic-like.	0.903
CARS	EARS2	A0A340Y2Y3	A0A340WSV7	cysteine--tRNA ligase, cytoplasmic isoform X2.	Probable glutamate--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.440
CARS	EPRS	A0A340Y2Y3	A0A340X885	cysteine--tRNA ligase, cytoplasmic isoform X2.	LOW QUALITY PROTEIN: bifunctional glutamate/proline--tRNA ligase.	0.671
CARS	GMPS	A0A340Y2Y3	A0A340XCB0	cysteine--tRNA ligase, cytoplasmic isoform X2.	GMP synthase [glutamine-hydrolyzing].	0.400
CARS	IARS	A0A340Y2Y3	A0A340Y3I1	cysteine--tRNA ligase, cytoplasmic isoform X2.	isoleucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.535
CARS	IARS2	A0A340Y2Y3	A0A340X633	cysteine--tRNA ligase, cytoplasmic isoform X2.	isoleucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.518
CARS	LARS	A0A340Y2Y3	A0A340XM35	cysteine--tRNA ligase, cytoplasmic isoform X2.	leucine--tRNA ligase, cytoplasmic isoform X1; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.725
CARS	LARS2	A0A340Y2Y3	A0A340XXM5	cysteine--tRNA ligase, cytoplasmic isoform X2.	Probable leucine--tRNA ligase, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.594
CARS	LOC103070928	A0A340Y2Y3	A0A340XEX1	cysteine--tRNA ligase, cytoplasmic isoform X2.	Probable methionine--tRNA ligase-like; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.612