(69 nodes) Protein-tyrosine phosphatase, active site network (Lipotes vexillifer)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	DUSP14	Dual specificity protein phosphatase 14; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (198 aa)
	PTPN9	Tyrosine-protein phosphatase non-receptor type 9. (593 aa)
	PTPRN	Receptor-type tyrosine-protein phosphatase-like N isoform X1. (979 aa)
	PTPRC	Receptor-type tyrosine-protein phosphatase C. (1121 aa)
	DUSP15	Dual specificity protein phosphatase 15; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (235 aa)
	CDC14B	Dual specificity protein phosphatase CDC14B isoform X1. (498 aa)
	PTPN1	Tyrosine-protein phosphatase non-receptor type. (440 aa)
	DUSP26	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (211 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	PTPN23	Tyrosine-protein phosphatase non-receptor type 23. (1630 aa)
	DUSP16	Dual specificity protein phosphatase 16. (647 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	DUSP5	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
	DUSP2	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (311 aa)
	PTPRZ1	Receptor-type tyrosine-protein phosphatase zeta. (2229 aa)
	MTMR6	Myotubularin-related protein 6. (621 aa)
	PTPRH	LOW QUALITY PROTEIN: protein tyrosine phosphatase, receptor type, H. (526 aa)
	TPTE2	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2-like. (519 aa)
	SSH1	Protein phosphatase Slingshot homolog 1. (1039 aa)
	MTMR4	Myotubularin-related protein 4 isoform X1. (1210 aa)
	LOC103071985	Probable tyrosine-protein phosphatase At1g05000-like. (207 aa)
	PTPN4	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa)
	PTPN12	Tyrosine-protein phosphatase non-receptor type 12 isoform X1. (782 aa)
	PTPN14	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1187 aa)
	CDC14A	Dual specificity protein phosphatase CDC14A. (624 aa)
	PTPN3	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (915 aa)
	SSH3	Protein phosphatase Slingshot homolog 3. (649 aa)
	EPM2A	Laforin. (331 aa)
	PTPRE	Receptor-type tyrosine-protein phosphatase epsilon isoform X1. (705 aa)
	MTMR2	Myotubularin-related protein 2 isoform X1. (643 aa)
	MTM1	Myotubularin isoform X1. (603 aa)
	MTMR14	Myotubularin-related protein 14 isoform X1. (648 aa)
	MTMR1	Myotubularin-related protein 1 isoform X1. (665 aa)
	SSH2	Protein phosphatase Slingshot homolog 2. (1429 aa)
	DUSP3	Dual specificity protein phosphatase 3 isoform X1. (239 aa)
	PTPRJ	Receptor-type tyrosine-protein phosphatase eta-like. (1155 aa)
	PTPRG	LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase gamma. (1389 aa)
	PTPRO	Receptor-type tyrosine-protein phosphatase O isoform X1. (1216 aa)
	PTPMT1	Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1. (201 aa)
	PTPRM	LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase mu. (1477 aa)
	LOC103074701	Dual specificity protein phosphatase 18-like; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (189 aa)
	MTMR7	Myotubularin-related protein 7. (660 aa)
	PTPRQ	Phosphatidylinositol phosphatase PTPRQ. (2299 aa)
	DUSP18	Dual specificity protein phosphatase 18; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (188 aa)
	PTPRK	Receptor-type tyrosine-protein phosphatase kappa isoform X1. (1461 aa)
	DUSP11	RNA/RNP complex-1-interacting phosphatase. (331 aa)
	PTPN22	Tyrosine-protein phosphatase non-receptor type 22 isoform X1. (808 aa)
	PTPRS	Receptor-type tyrosine-protein phosphatase S isoform X2. (1948 aa)
	PTPN21	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (1173 aa)
	PTPRU	Receptor-type tyrosine-protein phosphatase U isoform X1. (1446 aa)
	PTPRR	Receptor-type tyrosine-protein phosphatase R isoform X1. (653 aa)
	DUSP23	Dual specificity protein phosphatase 23. (150 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type 2. (289 aa)
	PTPN18	Tyrosine-protein phosphatase non-receptor type 18 isoform X1. (454 aa)
	PTPRN2	Receptor-type tyrosine-protein phosphatase N2. (1042 aa)
	PTPRA	Receptor-type tyrosine-protein phosphatase alpha. (802 aa)
	PTPRB	Receptor-type tyrosine-protein phosphatase beta isoform X1. (2213 aa)
	PTPRT	Receptor-type tyrosine-protein phosphatase T. (1452 aa)
	DUSP10	Dual specificity protein phosphatase 10 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (483 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
	DUSP8	LOW QUALITY PROTEIN: dual specificity protein phosphatase 8. (625 aa)
	DUPD1	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (221 aa)
	PTPN5	Tyrosine-protein phosphatase non-receptor type 5. (539 aa)
	PTPDC1	Protein tyrosine phosphatase domain-containing protein 1 isoform X1. (835 aa)
	PTPRF	Receptor-type tyrosine-protein phosphatase F isoform X2. (1910 aa)
	RNGTT	mRNA-capping enzyme. (299 aa)
	DUSP13	Dual specificity protein phosphatase 13 isoform B isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (327 aa)
	PTPRD	Receptor-type tyrosine-protein phosphatase delta isoform X1. (1506 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC14A	CDC14B	A0A340WRH0	A0A340WFI8	Dual specificity protein phosphatase CDC14A.	Dual specificity protein phosphatase CDC14B isoform X1.	0.933
CDC14A	EPM2A	A0A340WRH0	A0A340WTI3	Dual specificity protein phosphatase CDC14A.	Laforin.	0.448
CDC14B	CDC14A	A0A340WFI8	A0A340WRH0	Dual specificity protein phosphatase CDC14B isoform X1.	Dual specificity protein phosphatase CDC14A.	0.933
DUPD1	PTEN	A0A340Y1Q6	A0A340Y9L6	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.454
DUSP10	DUSP11	A0A340XYW9	A0A340XK71	Dual specificity protein phosphatase 10 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	RNA/RNP complex-1-interacting phosphatase.	0.454
DUSP11	DUSP10	A0A340XK71	A0A340XYW9	RNA/RNP complex-1-interacting phosphatase.	Dual specificity protein phosphatase 10 isoform X1; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.454
DUSP11	DUSP14	A0A340XK71	A0A340Y0D4	RNA/RNP complex-1-interacting phosphatase.	Dual specificity protein phosphatase 14; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.440
DUSP11	DUSP3	A0A340XK71	A0A340X0J1	RNA/RNP complex-1-interacting phosphatase.	Dual specificity protein phosphatase 3 isoform X1.	0.497
DUSP14	DUSP11	A0A340Y0D4	A0A340XK71	Dual specificity protein phosphatase 14; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	RNA/RNP complex-1-interacting phosphatase.	0.440
DUSP2	EPM2A	A0A340YFN2	A0A340WTI3	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Laforin.	0.439
DUSP26	PTPN3	A0A340WMP9	A0A340WS01	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton.	0.519
DUSP3	DUSP11	A0A340X0J1	A0A340XK71	Dual specificity protein phosphatase 3 isoform X1.	RNA/RNP complex-1-interacting phosphatase.	0.497
DUSP3	EPM2A	A0A340X0J1	A0A340WTI3	Dual specificity protein phosphatase 3 isoform X1.	Laforin.	0.506
DUSP3	PTPN5	A0A340X0J1	A0A340Y2E9	Dual specificity protein phosphatase 3 isoform X1.	Tyrosine-protein phosphatase non-receptor type 5.	0.907
DUSP3	PTPRA	A0A340X0J1	A0A340XW68	Dual specificity protein phosphatase 3 isoform X1.	Receptor-type tyrosine-protein phosphatase alpha.	0.438
DUSP3	PTPRR	A0A340X0J1	A0A340XQG2	Dual specificity protein phosphatase 3 isoform X1.	Receptor-type tyrosine-protein phosphatase R isoform X1.	0.910
EPM2A	CDC14A	A0A340WTI3	A0A340WRH0	Laforin.	Dual specificity protein phosphatase CDC14A.	0.448
EPM2A	DUSP2	A0A340WTI3	A0A340YFN2	Laforin.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.439
EPM2A	DUSP3	A0A340WTI3	A0A340X0J1	Laforin.	Dual specificity protein phosphatase 3 isoform X1.	0.506
MTM1	MTMR14	A0A340WX06	A0A340WXI8	Myotubularin isoform X1.	Myotubularin-related protein 14 isoform X1.	0.513