(26 nodes) AAA ATPase, AAA+ lid domain network (Lipotes vexillifer)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	PSMC3	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (423 aa)
	PSMC1	26S protease regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
	NSF	LOW QUALITY PROTEIN: N-ethylmaleimide-sensitive factor; Belongs to the AAA ATPase family. (644 aa)
	ATAD1	ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (404 aa)
	KATNAL1	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (490 aa)
	SPATA5	Spermatogenesis-associated protein 5. (887 aa)
	PSMC2	LOW QUALITY PROTEIN: 26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (477 aa)
	SPG7	LOW QUALITY PROTEIN: paraplegin. (793 aa)
	SPATA5L1	Spermatogenesis-associated protein 5-like protein 1 isoform X1. (767 aa)
	KATNAL2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (466 aa)
	VPS4B	Vacuolar protein sorting-associated protein 4B; Belongs to the AAA ATPase family. (443 aa)
	AFG3L2	LOW QUALITY PROTEIN: AFG3-like protein 2. (814 aa)
	PEX1	Peroxisome biogenesis factor 1. (1294 aa)
	LOC103072683	ATP-dependent zinc metalloprotease FTSH 5, chloroplastic-like; Belongs to the AAA ATPase family. (634 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
	PSMC4	26S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family. (418 aa)
	ATAD2	ATPase family AAA domain-containing protein 2. (1385 aa)
	PSMC5	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
	VCP	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (806 aa)
	ATAD2B	ATPase family AAA domain-containing protein 2B isoform X1. (1458 aa)
	NVL	Nuclear valosin-containing protein-like. (856 aa)
	LOC103076176	ATPase family AAA domain-containing protein 1-like. (84 aa)
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (616 aa)
	YME1L1	ATP-dependent zinc metalloprotease YME1L1 isoform X1. (715 aa)
	VPS4A	Vacuolar protein sorting-associated protein 4A; Belongs to the AAA ATPase family. (437 aa)
	PSMC6	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFG3L2	SPG7	A0A340XW32	A0A340Y5I2	LOW QUALITY PROTEIN: AFG3-like protein 2.	LOW QUALITY PROTEIN: paraplegin.	0.637
ATAD2	NVL	A0A340XA97	A0A340WYU1	ATPase family AAA domain-containing protein 2.	Nuclear valosin-containing protein-like.	0.423
ATAD2	PSMC3	A0A340XA97	A0A340X2L0	ATPase family AAA domain-containing protein 2.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.539
ATAD2	PSMC4	A0A340XA97	A0A340XBB0	ATPase family AAA domain-containing protein 2.	26S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family.	0.539
ATAD2	PSMC6	A0A340XA97	A0A340WG60	ATPase family AAA domain-containing protein 2.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.539
ATAD2B	PSMC3	A0A340X1U6	A0A340X2L0	ATPase family AAA domain-containing protein 2B isoform X1.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.539
ATAD2B	PSMC4	A0A340X1U6	A0A340XBB0	ATPase family AAA domain-containing protein 2B isoform X1.	26S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family.	0.539
ATAD2B	PSMC6	A0A340X1U6	A0A340WG60	ATPase family AAA domain-containing protein 2B isoform X1.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.539
KATNA1	PSMC3	A0A340XFE7	A0A340X2L0	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...]	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.539
KATNA1	PSMC4	A0A340XFE7	A0A340XBB0	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...]	26S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family.	0.539
KATNA1	PSMC6	A0A340XFE7	A0A340WG60	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...]	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.539
KATNAL1	PSMC3	A0A340YEX1	A0A340X2L0	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...]	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.539
KATNAL1	PSMC4	A0A340YEX1	A0A340XBB0	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...]	26S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family.	0.539
KATNAL1	PSMC6	A0A340YEX1	A0A340WG60	Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...]	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.539
KATNAL2	PSMC3	A0A340XZJ6	A0A340X2L0	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family.	0.850
KATNAL2	PSMC4	A0A340XZJ6	A0A340XBB0	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family.	0.850
KATNAL2	PSMC6	A0A340XZJ6	A0A340WG60	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	26S protease regulatory subunit 10B; Belongs to the AAA ATPase family.	0.850
LOC103072683	SPG7	A0A340XFP6	A0A340Y5I2	ATP-dependent zinc metalloprotease FTSH 5, chloroplastic-like; Belongs to the AAA ATPase family.	LOW QUALITY PROTEIN: paraplegin.	0.633
NVL	ATAD2	A0A340WYU1	A0A340XA97	Nuclear valosin-containing protein-like.	ATPase family AAA domain-containing protein 2.	0.423
PSMC1	PSMC2	A0A340YHK0	A0A340Y5W2	26S protease regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family.	LOW QUALITY PROTEIN: 26S protease regulatory subunit 7; Belongs to the AAA ATPase family.	0.998