STRINGSTRING
APH1B APH1B UBB UBB NRG2 NRG2 UBA52 UBA52 EREG EREG MXD4 MXD4 LOC103072471 LOC103072471 ADAP2 ADAP2 LOC103072950 LOC103072950 GRB2 GRB2 PIK3R1 PIK3R1 SHC1 SHC1 NRG3 NRG3 ESR1 ESR1 PSEN1 PSEN1 STMN1 STMN1 HBEGF HBEGF WWOX WWOX LOC103087231 LOC103087231 YAP1 YAP1 STAT5A STAT5A ITCH ITCH SOS1 SOS1 SRC SRC KRAS KRAS WWP1 WWP1 NCSTN NCSTN APH1A APH1A PSEN2 PSEN2 BTC BTC NRAS NRAS EGF EGF RPS27A RPS27A FNDC3A FNDC3A FNDC3B FNDC3B PIK3CA PIK3CA CSDE1 CSDE1 NRG1 NRG1 HRAS HRAS ADAP1 ADAP1 ERBB3 ERBB3 LOC103076597 LOC103076597 ERBB4 ERBB4 PSENEN PSENEN LOC103071927 LOC103071927 NRG4 NRG4 NEDD4 NEDD4 LOC103077771 LOC103077771 ERAS ERAS UBC UBC LOC103083100 LOC103083100 CSN2 CSN2 LOC103076438 LOC103076438
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APH1BGamma-secretase subunit APH-1B isoform X1. (257 aa)
UBBpolyubiquitin-C isoform X1. (305 aa)
NRG2Pro-neuregulin-2, membrane-bound isoform. (757 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
EREGProepiregulin. (163 aa)
MXD4Max dimerization protein 4. (211 aa)
LOC103072471Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (206 aa)
ADAP2arf-GAP with dual PH domain-containing protein 2 isoform X1. (383 aa)
LOC103072950Uncharacterized protein LOC103072950. (442 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform-like isoform X1. (613 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (468 aa)
STMN1Stathmin; Belongs to the stathmin family. (149 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
WWOXWW domain-containing oxidoreductase. (36 aa)
LOC103087231Yorkie homolog isoform X1. (489 aa)
YAP1Yorkie homolog. (430 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
SRCTyrosine-protein kinase. (548 aa)
KRASGTPase KRas. (188 aa)
WWP1E3 ubiquitin-protein ligase. (922 aa)
NCSTNNicastrin isoform X1. (709 aa)
APH1AGamma-secretase subunit APH-1A isoform X1. (340 aa)
PSEN2Presenilin-2. (407 aa)
BTCProbetacellulin. (178 aa)
NRASGTPase NRas. (189 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (843 aa)
NRG1Pro-neuregulin-3, membrane-bound isoform-like isoform X1. (641 aa)
HRASGTPase HRas isoform X1. (189 aa)
ADAP1arf-GAP with dual PH domain-containing protein 1 isoform X1. (374 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3. (1338 aa)
LOC103076597ubiquitin-40S ribosomal protein S27a-like. (187 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
PSENENGamma-secretase subunit PEN-2. (101 aa)
LOC103071927WW domain-containing oxidoreductase-like. (243 aa)
NRG4Pro-neuregulin-4, membrane-bound isoform. (116 aa)
NEDD4E3 ubiquitin-protein ligase. (782 aa)
LOC103077771E3 ubiquitin-protein ligase NEDD4-like. (515 aa)
ERASGTPase ERas. (233 aa)
UBCpolyubiquitin-C. (462 aa)
LOC103083100ubiquitin-60S ribosomal protein L40-like. (116 aa)
CSN2Beta-casein; Important role in determination of the surface properties of the casein micelles. (224 aa)
LOC103076438ubiquitin-40S ribosomal protein S27a-like. (155 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.