16 items (Lipotes vexillifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SRC	Tyrosine-protein kinase. (548 aa)
	SOS1	Son of sevenless homolog 1. (1333 aa)
	KITLG	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (274 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (910 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	LYN	Tyrosine-protein kinase. (516 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1206 aa)
	SH2B3	SH2B adapter protein 3. (573 aa)
	LCK	Tyrosine-protein kinase. (520 aa)
	SH2B2	SH2B adapter protein 2. (660 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBL	FYN	A0A340X461	A0A340WT33	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.946
CBL	GRB2	A0A340X461	A0A340X5P7	E3 ubiquitin-protein ligase CBL.	Growth factor receptor-bound protein 2 isoform X1.	0.997
CBL	KIT	A0A340X461	A0A340XAV1	E3 ubiquitin-protein ligase CBL.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.709
CBL	KITLG	A0A340X461	A0A340WQ37	E3 ubiquitin-protein ligase CBL.	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.	0.518
CBL	LCK	A0A340X461	A0A340YBD8	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.797
CBL	LYN	A0A340X461	A0A340XV93	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.929
CBL	PTPN6	A0A340X461	A0A340YDE6	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.495
CBL	SH2B2	A0A340X461	A0A340YBS8	E3 ubiquitin-protein ligase CBL.	SH2B adapter protein 2.	0.972
CBL	SH2B3	A0A340X461	A0A340Y0C0	E3 ubiquitin-protein ligase CBL.	SH2B adapter protein 3.	0.608
CBL	SOS1	A0A340X461	A0A340WF86	E3 ubiquitin-protein ligase CBL.	Son of sevenless homolog 1.	0.570
CBL	SRC	A0A340X461	A0A340WDY6	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.874
CBL	YES1	A0A340X461	A0A340XGB1	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase.	0.733
FYN	CBL	A0A340WT33	A0A340X461	Tyrosine-protein kinase.	E3 ubiquitin-protein ligase CBL.	0.946
FYN	GRB2	A0A340WT33	A0A340X5P7	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2 isoform X1.	0.658
FYN	KIT	A0A340WT33	A0A340XAV1	Tyrosine-protein kinase.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.507
FYN	KITLG	A0A340WT33	A0A340WQ37	Tyrosine-protein kinase.	Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family.	0.402
FYN	LCK	A0A340WT33	A0A340YBD8	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.963
FYN	LYN	A0A340WT33	A0A340XV93	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.993
FYN	PTPN6	A0A340WT33	A0A340YDE6	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.692
FYN	SH2B2	A0A340WT33	A0A340YBS8	Tyrosine-protein kinase.	SH2B adapter protein 2.	0.488