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| | ULK1 | Serine/threonine-protein kinase ULK1. (1055 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa) |
| | SRC | Tyrosine-protein kinase. (548 aa) |
| | CHMP4B | Charged multivesicular body protein 4b. (224 aa) |
| | ATG9A | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (870 aa) |
| | ATG16L1 | Autophagy-related protein 16-1 isoform X1. (607 aa) |
| | TUBA4A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (482 aa) |
| | PRKAG3 | 5'-AMP-activated protein kinase subunit gamma-3 isoform X3. (482 aa) |
| | LOC103082790 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (427 aa) |
| | ATG14 | Beclin 1-associated autophagy-related key regulator. (414 aa) |
| | PRKAB2 | 5'-AMP-activated protein kinase subunit beta-2. (272 aa) |
| | TM9SF1 | Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (633 aa) |
| | DYNC1I2 | Cytoplasmic dynein 1 intermediate chain 2 isoform X1. (638 aa) |
| | ZCCHC3 | Zinc finger CCHC domain-containing protein 3 isoform X1. (406 aa) |
| | DYNLL1 | Dynein light chain. (89 aa) |
| | CSNK2A1 | Casein kinase II subunit alpha isoform X1; Belongs to the protein kinase superfamily. (391 aa) |
| | TUBB1 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (480 aa) |
| | WIPI2 | WD repeat domain phosphoinositide-interacting protein 2 isoform X1. (436 aa) |
| | BECN1 | Beclin-1 isoform X1. (448 aa) |
| | MDP1 | Magnesium-dependent phosphatase 1 isoform X1. (164 aa) |
| | USP30 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa) |
| | MAP1LC3A | Microtubule-associated proteins 1A/1B light chain 3A. (121 aa) |
| | CHMP4A | Charged multivesicular body protein 4a. (222 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1482 aa) |
| | GSAP | Gamma-secretase-activating protein. (854 aa) |
| | UBC | polyubiquitin-C. (462 aa) |
| | LAMTOR5 | Ragulator complex protein LAMTOR5. (91 aa) |
| | ATG12 | Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa) |
| | LOC103083100 | ubiquitin-60S ribosomal protein L40-like. (116 aa) |
| | ATG10 | Ubiquitin-like-conjugating enzyme ATG10. (234 aa) |
| | PRKAG1 | 5'-AMP-activated protein kinase subunit gamma-1 isoform X2. (336 aa) |
| | LOC103069618 | GTP-binding protein Rheb-like. (184 aa) |
| | LOC103091095 | Protein Njmu-R1. (395 aa) |
| | NBR1 | Next to BRCA1 gene 1 protein. (866 aa) |
| | DYNC1I1 | Cytoplasmic dynein 1 intermediate chain 1 isoform X1. (645 aa) |
| | HDAC6 | Histone deacetylase 6. (1142 aa) |
| | TUBE1 | Tubulin epsilon chain; Belongs to the tubulin family. (475 aa) |
| | WDR45 | WD repeat domain phosphoinositide-interacting protein 4 isoform X1. (361 aa) |
| | LOC103088880 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (720 aa) |
| | LOC103076438 | ubiquitin-40S ribosomal protein S27a-like. (155 aa) |
| | RRAGC | LOW QUALITY PROTEIN: ras-related GTP-binding protein C. (406 aa) |
| | TUBA1C | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (414 aa) |
| | MTMR14 | Myotubularin-related protein 14 isoform X1. (648 aa) |
| | ATG101 | Autophagy-related protein 101. (218 aa) |
| | TOMM22 | Mitochondrial import receptor subunit TOM22 homolog. (142 aa) |
| | LOC103076433 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa) |
| | LOC103079668 | Tubulin beta-2A chain-like. (168 aa) |
| | MTERFD1 | mTERF domain-containing protein 1, mitochondrial. (414 aa) |
| | TUBA1B | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (416 aa) |
| | LOC103075538 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa) |
| | RHEBL1 | GTPase RhebL1. (183 aa) |
| | TUBA1A | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (416 aa) |
| | UVRAG | UV radiation resistance-associated gene protein isoform X1. (699 aa) |
| | MLST8 | Target of rapamycin complex subunit LST8 isoform X1. (326 aa) |
| | WIPI1 | WD repeat domain phosphoinositide-interacting protein 1. (447 aa) |
| | TSC1 | Hamartin isoform X1. (1170 aa) |
| | TOMM20 | Mitochondrial import receptor subunit TOM20 homolog. (145 aa) |
| | TOMM70A | Mitochondrial import receptor subunit TOM70. (609 aa) |
| | PARK7 | Protein DJ-1. (189 aa) |
| | ATG13 | Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (551 aa) |
| | AMBRA1 | Activating molecule in BECN1-regulated autophagy protein 1 isoform X1. (1205 aa) |
| | TSC2 | Tuberin. (1793 aa) |
| | RRAGB | Ras-related GTP-binding protein B-like isoform X1. (374 aa) |
| | LOC103086172 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa) |
| | LOC103086727 | Uncharacterized protein LOC103086727. (400 aa) |
| | LOC103072950 | Uncharacterized protein LOC103072950. (442 aa) |
| | LOC103075565 | FUN14 domain-containing protein 1-like. (155 aa) |
| | LOC103081682 | Gamma-aminobutyric acid receptor-associated protein-like 1-like. (60 aa) |
| | PLIN2 | Perilipin; Belongs to the perilipin family. (455 aa) |
| | DYNC1H1 | Cytoplasmic dynein 1 heavy chain 1. (4620 aa) |
| | LOC103089543 | Charged multivesicular body protein 7-like. (100 aa) |
| | PGAM5 | Serine/threonine-protein phosphatase PGAM5, mitochondrial isoform X1. (289 aa) |
| | CETN1 | Centrin-1. (172 aa) |
| | GABARAP | Gamma-aminobutyric acid receptor-associated protein. (117 aa) |
| | WDR45B | WD repeat domain phosphoinositide-interacting protein 3. (344 aa) |
| | ATG3 | Autophagy-related protein 3. (314 aa) |
| | DYNC1LI2 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa) |
| | CHMP2A | Charged multivesicular body protein 2a. (222 aa) |
| | PARK2 | RBR-type E3 ubiquitin transferase. (274 aa) |
| | LOC103073687 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (415 aa) |
| | LAMTOR2 | Ragulator complex protein LAMTOR2 isoform X1. (125 aa) |
| | CHMP7 | Charged multivesicular body protein 7-like. (450 aa) |
| | TUBB4B | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | PINK1 | Serine/threonine-protein kinase PINK1, mitochondrial. (571 aa) |
| | TOMM40 | Mitochondrial import receptor subunit TOM40 homolog isoform X1. (361 aa) |
| | CSNK2B | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (249 aa) |
| | KXD1 | kxDL motif-containing protein 1. (176 aa) |
| | CRYBB3 | Beta-crystallin B3 isoform X1; Belongs to the beta/gamma-crystallin family. (211 aa) |
| | KIAA1671 | Uncharacterized protein KIAA1671 homolog. (1811 aa) |
| | LY6G5B | Lymphocyte antigen 6 complex locus protein G5b. (218 aa) |
| | BECN1P1 | Beclin-2. (432 aa) |
| | VDAC1 | Voltage-dependent anion-selective channel protein 1 isoform X1. (283 aa) |
| | UBB | polyubiquitin-C isoform X1. (305 aa) |
| | ULK2 | Serine/threonine-protein kinase ULK2. (952 aa) |
| | ATG4D | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (471 aa) |
| | GABARAPL2 | Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa) |
| | CHMP4C | Charged multivesicular body protein 4c. (237 aa) |
| | LAMTOR1 | Ragulator complex protein LAMTOR1. (161 aa) |
| | UBA52 | ubiquitin-60S ribosomal protein L40. (128 aa) |
| | MFN2 | Mitofusin-2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa) |
| | MTMR3 | LOW QUALITY PROTEIN: myotubularin-related protein 3. (1205 aa) |
| | LOC103090066 | LOW QUALITY PROTEIN: microtubule-associated proteins 1A/1B light chain 3C-like. (145 aa) |
| | RB1CC1 | RB1-inducible coiled-coil protein 1. (1589 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | ATG4C | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa) |
| | CHMP6 | Charged multivesicular body protein 6. (202 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2544 aa) |
| | IFT88 | Intraflagellar transport protein 88 homolog. (825 aa) |
| | RPTOR | Regulatory-associated protein of mTOR isoform X1. (1335 aa) |
| | PIK3R4 | Phosphoinositide 3-kinase regulatory subunit 4. (1358 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | ATG4A | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (398 aa) |
| | PRKAB1 | 5'-AMP-activated protein kinase subunit beta-1. (270 aa) |
| | LAMTOR3 | Ragulator complex protein LAMTOR3. (124 aa) |
| | TXNDC11 | Thioredoxin domain-containing protein 11. (958 aa) |
| | TUBB6 | Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (374 aa) |
| | ARL13B | ADP-ribosylation factor-like protein 13B isoform X1. (430 aa) |
| | RPS27A | ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | TUBAL3 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (530 aa) |
| | DYNLL2 | Dynein light chain. (89 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | RRAGD | Ras-related GTP-binding protein D. (396 aa) |
| | FNDC3A | Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa) |
| | SQSTM1 | Sequestosome-1. (440 aa) |
| | MFN1 | Mitofusin-1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (742 aa) |
| | FNDC3B | Fibronectin type III domain-containing protein 3B. (1206 aa) |
| | LOC103089565 | Uncharacterized protein LOC103089565. (301 aa) |
| | DYNC1LI1 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa) |
| | LOC103069326 | Uncharacterized protein C6orf106 homolog. (215 aa) |
| | PEX5L | PEX5-related protein isoform X1. (650 aa) |
| | CSNK2A2 | Casein kinase II subunit alpha. (213 aa) |
| | MAP1LC3B | Microtubule-associated proteins 1A/1B light chain 3B isoform X1. (125 aa) |
| | TOMM40L | Mitochondrial import receptor subunit TOM40B isoform X1. (339 aa) |
| | LOC103085022 | Charged multivesicular body protein 7-like. (305 aa) |
| | CHMP3 | Charged multivesicular body protein 3. (221 aa) |
| | CHMP2B | Charged multivesicular body protein 2b isoform X1. (213 aa) |
| | LOC103076597 | ubiquitin-40S ribosomal protein S27a-like. (187 aa) |
| | LAMTOR4 | Ragulator complex protein LAMTOR4. (99 aa) |
| | FUNDC2 | FUN14 domain-containing protein 2. (189 aa) |
| | LOC103076330 | FUN14 domain-containing protein 2-like. (257 aa) |
| | CETN3 | Centrin-3. (167 aa) |
| | PRKAG2 | 5'-AMP-activated protein kinase subunit gamma-2 isoform X1. (569 aa) |
| | UBE2N | Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | SLC38A9 | Putative sodium-coupled neutral amino acid transporter 9 isoform X1. (561 aa) |
| | PEX5 | Peroxisomal targeting signal 1 receptor isoform X1. (656 aa) |
| | LOC103082376 | Uncharacterized protein LOC103082376; Belongs to the tubulin family. (926 aa) |
| | LOC103083735 | E3 ubiquitin-protein ligase parkin-like. (141 aa) |
| | TUBA8 | Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa) |
| | ATG9B | Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (910 aa) |
| | ATG4B | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa) |
| | GABARAPL1 | Gamma-aminobutyric acid receptor-associated protein-like 1. (107 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | RHEB | GTP-binding protein Rheb. (184 aa) |
| | CRYGN | Gamma-crystallin N; Belongs to the beta/gamma-crystallin family. (183 aa) |
| | LOC103076627 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (348 aa) |
| | RRAGA | LOW QUALITY PROTEIN: Ras-related GTP binding A. (318 aa) |
| | LOC103078288 | LOW QUALITY PROTEIN: uncharacterized protein C6orf106 homolog. (405 aa) |
