15 items (Lipotes vexillifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AREG	Amphiregulin isoform X1. (254 aa)
	EGFR	Receptor protein-tyrosine kinase. (1209 aa)
	SOS1	Son of sevenless homolog 1. (1333 aa)
	HRAS	GTPase HRas isoform X1. (189 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
	NRAS	GTPase NRas. (189 aa)
	EPGN	Epigen isoform X1. (153 aa)
	BTC	Probetacellulin. (178 aa)
	ERAS	GTPase ERas. (233 aa)
	TGFA	Protransforming growth factor alpha. (145 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	HBEGF	Proheparin-binding EGF-like growth factor. (208 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (843 aa)
	EREG	Proepiregulin. (163 aa)
	KRAS	GTPase KRas. (188 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AREG	BTC	A0A340XPE8	A0A340XSV2	Amphiregulin isoform X1.	Probetacellulin.	0.836
AREG	EGF	A0A340XPE8	A0A340XVB5	Amphiregulin isoform X1.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.721
AREG	EGFR	A0A340XPE8	A0A340XQY3	Amphiregulin isoform X1.	Receptor protein-tyrosine kinase.	0.994
AREG	EPGN	A0A340XPE8	A0A340XSV7	Amphiregulin isoform X1.	Epigen isoform X1.	0.792
AREG	EREG	A0A340XPE8	A0A340XPM9	Amphiregulin isoform X1.	Proepiregulin.	0.884
AREG	GRB2	A0A340XPE8	A0A340X5P7	Amphiregulin isoform X1.	Growth factor receptor-bound protein 2 isoform X1.	0.418
AREG	HBEGF	A0A340XPE8	A0A340XJA1	Amphiregulin isoform X1.	Proheparin-binding EGF-like growth factor.	0.643
AREG	KRAS	A0A340XPE8	A0A340WCQ7	Amphiregulin isoform X1.	GTPase KRas.	0.690
AREG	NRAS	A0A340XPE8	A0A340XT90	Amphiregulin isoform X1.	GTPase NRas.	0.402
AREG	TGFA	A0A340XPE8	A0A340X0Q8	Amphiregulin isoform X1.	Protransforming growth factor alpha.	0.773
BTC	AREG	A0A340XSV2	A0A340XPE8	Probetacellulin.	Amphiregulin isoform X1.	0.836
BTC	EGF	A0A340XSV2	A0A340XVB5	Probetacellulin.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.742
BTC	EGFR	A0A340XSV2	A0A340XQY3	Probetacellulin.	Receptor protein-tyrosine kinase.	0.985
BTC	EPGN	A0A340XSV2	A0A340XSV7	Probetacellulin.	Epigen isoform X1.	0.825
BTC	EREG	A0A340XSV2	A0A340XPM9	Probetacellulin.	Proepiregulin.	0.738
BTC	GRB2	A0A340XSV2	A0A340X5P7	Probetacellulin.	Growth factor receptor-bound protein 2 isoform X1.	0.457
BTC	HBEGF	A0A340XSV2	A0A340XJA1	Probetacellulin.	Proheparin-binding EGF-like growth factor.	0.833
BTC	KRAS	A0A340XSV2	A0A340WCQ7	Probetacellulin.	GTPase KRas.	0.539
BTC	TGFA	A0A340XSV2	A0A340X0Q8	Probetacellulin.	Protransforming growth factor alpha.	0.493
CSDE1	EGFR	A0A340XM96	A0A340XQY3	Cold shock domain-containing protein E1 isoform X1.	Receptor protein-tyrosine kinase.	0.485