STRINGSTRING
PIK3R1 PIK3R1 GRB2 GRB2 LPXN LPXN TGFA TGFA TGFB1I1 TGFB1I1 PXN PXN CSK CSK SRC SRC PTPN11 PTPN11 PAG1 PAG1 PIK3CA PIK3CA FNDC3B FNDC3B FNDC3A FNDC3A BTC BTC EGFR EGFR EREG EREG AREG AREG HBEGF HBEGF RNF222 RNF222 EGF EGF EPGN EPGN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
LPXNLeupaxin isoform X2; Belongs to the paxillin family. (387 aa)
TGFAProtransforming growth factor alpha. (145 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (456 aa)
PXNPaxillin-like isoform X1; Belongs to the paxillin family. (591 aa)
CSKTyrosine-protein kinase. (450 aa)
SRCTyrosine-protein kinase. (548 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
PAG1Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (519 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
BTCProbetacellulin. (178 aa)
EGFRReceptor protein-tyrosine kinase. (1209 aa)
EREGProepiregulin. (163 aa)
AREGAmphiregulin isoform X1. (254 aa)
HBEGFProheparin-binding EGF-like growth factor. (208 aa)
RNF222RING finger protein 222. (211 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
EPGNEpigen isoform X1. (153 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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