STRINGSTRING
COL6A2 COL6A2 PLCG1 PLCG1 COL5A2 COL5A2 GRB7 GRB7 NEDD9 NEDD9 COL2A1 COL2A1 LOC103069117 LOC103069117 FNDC3A FNDC3A PIK3CB PIK3CB FNDC3B FNDC3B PIK3CA PIK3CA COL3A1 COL3A1 PDGFA PDGFA HRAS HRAS CSDE1 CSDE1 COL6A6 COL6A6 PIK3R2 PIK3R2 COL9A3 COL9A3 PCSK4 PCSK4 THBS1 THBS1 COL5A3 COL5A3 THBS3 THBS3 LOC103073034 LOC103073034 NCK1 NCK1 PLAT PLAT PIK3R1 PIK3R1 NCK2 NCK2 GRB2 GRB2 PDGFB PDGFB COL9A2 COL9A2 PDGFRA PDGFRA COL5A1 COL5A1 COL4A1 COL4A1 NRAS NRAS CRK CRK COL6A3 COL6A3 RAPGEF1 RAPGEF1 COL6A1 COL6A1 PDGFD PDGFD PTPN12 PTPN12 CRKL CRKL ERAS ERAS SPP1 SPP1 PDGFRB PDGFRB EFS EFS THBS4 THBS4 LOC103088885 LOC103088885 FURIN FURIN PTPN11 PTPN11 STAT6 STAT6 THBS2 THBS2 KRAS KRAS LOC103087942 LOC103087942 SRC SRC STAT5B STAT5B SOS1 SOS1 STAT5A STAT5A STAT3 STAT3 COL9A1 COL9A1 RASA1 RASA1 COL6A5 COL6A5 BCAR1 BCAR1 PDGFC PDGFC CASS4 CASS4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL6A2Collagen alpha-2(VI) chain isoform X1. (1027 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
COL5A2Collagen alpha-2(V) chain. (1499 aa)
GRB7LOW QUALITY PROTEIN: growth factor receptor-bound protein 7. (557 aa)
NEDD9Enhancer of filamentation 1-like. (819 aa)
COL2A1Collagen alpha-1(II) chain isoform X1. (1487 aa)
LOC103069117LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-like. (721 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
COL3A1Collagen alpha-1(III) chain-like. (1462 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (211 aa)
HRASGTPase HRas isoform X1. (189 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (843 aa)
COL6A6LOW QUALITY PROTEIN: collagen alpha-6(VI) chain. (2282 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
COL9A3Collagen alpha-3(IX) chain. (684 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (843 aa)
THBS1Thrombospondin-1. (1170 aa)
COL5A3Collagen alpha-3(V) chain isoform X1. (1744 aa)
THBS3Thrombospondin-3. (957 aa)
LOC103073034Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (814 aa)
NCK1Cytoplasmic protein. (377 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
NCK2Cytoplasmic protein. (376 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
PDGFBPlatelet-derived growth factor subunit B isoform X1; Belongs to the PDGF/VEGF growth factor family. (241 aa)
COL9A2Collagen alpha-2(IX) chain. (691 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
COL5A1Collagen alpha-1(V) chain isoform X1. (1841 aa)
COL4A1Collagen alpha-1(IV) chain. (1668 aa)
NRASGTPase NRas. (189 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
COL6A3LOW QUALITY PROTEIN: collagen alpha-3(VI) chain. (2962 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1 isoform X1. (1133 aa)
COL6A1Collagen alpha-1(VI) chain. (1150 aa)
PDGFDPlatelet-derived growth factor D-like isoform X1. (370 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12 isoform X1. (782 aa)
CRKLCrk-like protein. (303 aa)
ERASGTPase ERas. (233 aa)
SPP1Osteopontin isoform X1. (296 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1103 aa)
EFSEmbryonal Fyn-associated substrate isoform X1. (560 aa)
THBS4Thrombospondin-4. (961 aa)
LOC103088885Collagen alpha-5(VI) chain-like. (2189 aa)
FURINFurin isoform X1; Belongs to the peptidase S8 family. (792 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
THBS2LOW QUALITY PROTEIN: thrombospondin-2. (1235 aa)
KRASGTPase KRas. (188 aa)
LOC103087942Signal transducer and activator of transcription 5A-like. (237 aa)
SRCTyrosine-protein kinase. (548 aa)
STAT5BSignal transducer and activator of transcription. (792 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
STAT3Signal transducer and activator of transcription. (654 aa)
COL9A1Collagen alpha-1(IX) chain isoform X1. (925 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
COL6A5Collagen alpha-5(VI) chain. (440 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1 isoform X1. (867 aa)
PDGFCPlatelet-derived growth factor C. (345 aa)
CASS4Cas scaffolding protein family member 4. (801 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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