STRINGSTRING
WASF2 WASF2 CDC42 CDC42 CTNNA1 CTNNA1 STX12 STX12 SZRD1 SZRD1 SHC2 SHC2 PGF PGF PIK3R2 PIK3R2 ACTG1 ACTG1 BAIAP2 BAIAP2 ARVCF ARVCF CSDE1 CSDE1 SHD SHD SPHK1 SPHK1 PRKCA PRKCA SHC4 SHC4 TENM4 TENM4 HSP90AA1 HSP90AA1 LOC103084779 LOC103084779 PRR5 PRR5 PDPK1 PDPK1 LPXN LPXN MAPK12 MAPK12 ABI2 ABI2 STX7 STX7 NCK2 NCK2 PIK3R1 PIK3R1 ELMO3 ELMO3 CDH5 CDH5 SHB SHB NCKAP1 NCKAP1 CTNND1 CTNND1 ITGB3 ITGB3 NCK1 NCK1 ROCK2 ROCK2 PRKACB PRKACB RNF222 RNF222 TENM2 TENM2 LOC103085751 LOC103085751 VAV3 VAV3 RASA1 RASA1 ELMO2 ELMO2 PXN PXN TENM1 TENM1 ELMO1 ELMO1 ACTB ACTB SRC SRC KRAS KRAS PRKCD PRKCD LOC103069874 LOC103069874 CYFIP2 CYFIP2 RHOA RHOA CALM1 CALM1 FLT1 FLT1 ITGAV ITGAV FNDC3B FNDC3B PIK3CA PIK3CA MAPK14 MAPK14 JUP JUP SHF SHF FLT4 FLT4 SH2D2A SH2D2A THEM4 THEM4 VEGFA VEGFA CALM3 CALM3 ACTL8 ACTL8 AXL AXL RICTOR RICTOR MAPK13 MAPK13 LOC103074541 LOC103074541 HRAS HRAS LOC103090543 LOC103090543 PRKACA PRKACA LOC103077596 LOC103077596 NCKAP1L NCKAP1L NCF1 NCF1 VAV1 VAV1 PAK1 PAK1 HSH2D HSH2D VEGFB VEGFB BCAR1 BCAR1 CASS4 CASS4 NRAS NRAS PLCG1 PLCG1 CYFIP1 CYFIP1 NEDD9 NEDD9 PAK2 PAK2 FIGF FIGF PTK2B PTK2B FNDC3A FNDC3A PIK3CB PIK3CB PAK3 PAK3 CTNNB1 CTNNB1 PTK2 PTK2 HSPB1 HSPB1 NRP2 NRP2 MAPKAPK2 MAPKAPK2 ABI1 ABI1 TENM3 TENM3 NRP1 NRP1 NOS3 NOS3 WASF3 WASF3 SHE SHE EFS EFS RAC1 RAC1 PRKCZ PRKCZ PRKCB PRKCB ERAS ERAS VEGFC VEGFC LOC103082455 LOC103082455 LOC103080281 LOC103080281 FYN FYN WASF1 WASF1 KDR KDR NCF2 NCF2 VAV2 VAV2 TGFB1I1 TGFB1I1 CAV1 CAV1 DOCK1 DOCK1 NCF4 NCF4 MAPKAPK3 MAPKAPK3 MAPK11 MAPK11 CRK CRK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WASF2wiskott-Aldrich syndrome protein family member 2 isoform X1. (498 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
CTNNA1Catenin alpha-1 isoform X1. (906 aa)
STX12Syntaxin-12; Belongs to the syntaxin family. (274 aa)
SZRD1SUZ domain-containing protein 1. (151 aa)
SHC2SHC-transforming protein 2. (801 aa)
PGFPlacenta growth factor isoform X1; Belongs to the PDGF/VEGF growth factor family. (170 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (535 aa)
ARVCFArmadillo repeat protein deleted in velo-cardio-facial syndrome. (960 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (843 aa)
SHDSH2 domain-containing adapter protein D. (340 aa)
SPHK1Sphingosine kinase 1. (484 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
SHC4SHC-transforming protein 4 isoform X1. (631 aa)
TENM4Teneurin-4-like. (2768 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (732 aa)
LOC103084779Teneurin-1-like. (1934 aa)
PRR5Proline-rich protein 5. (388 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
LPXNLeupaxin isoform X2; Belongs to the paxillin family. (387 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
ABI2Abl interactor 2 isoform X1. (540 aa)
STX7Syntaxin-7; Belongs to the syntaxin family. (261 aa)
NCK2Cytoplasmic protein. (376 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
ELMO3Engulfment and cell motility protein 3 isoform X1. (720 aa)
CDH5Cadherin-5; Cadherins are calcium-dependent cell adhesion proteins. (782 aa)
SHBLOW QUALITY PROTEIN: SH2 domain-containing adapter protein B. (595 aa)
NCKAP1Nck-associated protein 1. (1126 aa)
CTNND1Catenin delta-1 isoform X1. (978 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
NCK1Cytoplasmic protein. (377 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1389 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta. (274 aa)
RNF222RING finger protein 222. (211 aa)
TENM2Teneurin-2-like. (2773 aa)
LOC103085751Junction plakoglobin-like. (330 aa)
VAV3Guanine nucleotide exchange factor VAV3 isoform X1. (875 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
ELMO2Engulfment and cell motility protein 2 isoform X3. (732 aa)
PXNPaxillin-like isoform X1; Belongs to the paxillin family. (591 aa)
TENM1Teneurin-1-like. (530 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (742 aa)
ACTBActin, cytoplasmic 1. (375 aa)
SRCTyrosine-protein kinase. (548 aa)
KRASGTPase KRas. (188 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
LOC103069874Abl interactor 1-like. (235 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
RHOATransforming protein RhoA isoform X1. (221 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
FLT1Vascular endothelial growth factor receptor 1 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1339 aa)
ITGAVIntegrin alpha-V; Belongs to the integrin alpha chain family. (1311 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
JUPJunction plakoglobin. (330 aa)
SHFSH2 domain-containing adapter protein F. (367 aa)
FLT4Vascular endothelial growth factor receptor 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1594 aa)
SH2D2ASH2 domain-containing protein 2A isoform X1. (406 aa)
THEM4Acyl-coenzyme A thioesterase THEM4. (239 aa)
VEGFAVascular endothelial growth factor A isoform X1; Belongs to the PDGF/VEGF growth factor family. (214 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
AXLTyrosine-protein kinase receptor UFO isoform X1. (887 aa)
RICTORRapamycin-insensitive companion of mTOR-like isoform X1. (1580 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
LOC103074541LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
HRASGTPase HRas isoform X1. (189 aa)
LOC103090543Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (192 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
LOC103077596Teneurin-3-like. (241 aa)
NCKAP1LNck-associated protein 1-like. (1134 aa)
NCF1Neutrophil cytosol factor 1. (393 aa)
VAV1Proto-oncogene vav isoform X1. (844 aa)
PAK1Non-specific serine/threonine protein kinase. (563 aa)
HSH2DHematopoietic SH2 domain-containing protein. (346 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (207 aa)
BCAR1Breast cancer anti-estrogen resistance protein 1 isoform X1. (867 aa)
CASS4Cas scaffolding protein family member 4. (801 aa)
NRASGTPase NRas. (189 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
NEDD9Enhancer of filamentation 1-like. (819 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
FIGFVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PAK3Serine/threonine-protein kinase PAK 3 isoform X1. (579 aa)
CTNNB1Catenin beta-1 isoform X1. (781 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1003 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (201 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (388 aa)
ABI1Abl interactor 1-like isoform X1. (379 aa)
TENM3Teneurin-3-like. (2436 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (924 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
WASF3wiskott-Aldrich syndrome protein family member 3. (502 aa)
SHELOW QUALITY PROTEIN: Src homology 2 domain containing E. (519 aa)
EFSEmbryonal Fyn-associated substrate isoform X1. (560 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (201 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ERASGTPase ERas. (233 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (420 aa)
LOC103082455Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
LOC103080281Probable protein BRICK1-like. (75 aa)
FYNTyrosine-protein kinase. (537 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (559 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
NCF2Neutrophil cytosol factor 2 isoform X1. (526 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (878 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Belongs to the paxillin family. (456 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
DOCK1Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (1886 aa)
NCF4Neutrophil cytosol factor 4. (339 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (384 aa)
MAPK11Mitogen-activated protein kinase. (350 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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