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PLA2G6 PLA2G6 PLCG2 PLCG2 MYO1D MYO1D SYK SYK ACTB ACTB ELMO1 ELMO1 NCKIPSD NCKIPSD ELMO2 ELMO2 ARPC1B ARPC1B MYO10 MYO10 ARPC5 ARPC5 VAV3 VAV3 LOC103073174 LOC103073174 ARPC4 ARPC4 LOC103091002 LOC103091002 ABL1 ABL1 DOCK1 DOCK1 VAV2 VAV2 IGLL5 IGLL5 ARPC5L ARPC5L WASF1 WASF1 LOC103080281 LOC103080281 LOC103079081 LOC103079081 WIPF1 WIPF1 ARPC2 ARPC2 ARPC3 ARPC3 LOC103084661 LOC103084661 MAPK1 MAPK1 WAS WAS RAC1 RAC1 ARPC1A ARPC1A MYO1H MYO1H MYO1G MYO1G CYFIP2 CYFIP2 LOC103069874 LOC103069874 PRKCD PRKCD LOC103070587 LOC103070587 LOC103090824 LOC103090824 WASL WASL WASF3 WASF3 ACTR3B ACTR3B ABI1 ABI1 PPAPDC1B PPAPDC1B LOC103082646 LOC103082646 NCKAP1L NCKAP1L PPAPDC1A PPAPDC1A MYO1A MYO1A LIMK1 LIMK1 WIPF3 WIPF3 LOC103076856 LOC103076856 MYO1B MYO1B PIK3CA PIK3CA PLD1 PLD1 PTK2 PTK2 PIK3CB PIK3CB ACTR2 ACTR2 CFL2 CFL2 LOC103069126 LOC103069126 WIPF2 WIPF2 LOC103074911 LOC103074911 CYFIP1 CYFIP1 PLCG1 PLCG1 FMN1 FMN1 PLD5 PLD5 MYO5C MYO5C MYO5A MYO5A CFL1 CFL1 PAK1 PAK1 VAV1 VAV1 BAIAP2 BAIAP2 ACTG1 ACTG1 PIK3R2 PIK3R2 DSTN DSTN CDC42 CDC42 PRKCE PRKCE WASF2 WASF2 NF2 NF2 ACTL8 ACTL8 LOC103088736 LOC103088736 LOC103068717 LOC103068717 HSP90AB1 HSP90AB1 NCK1 NCK1 CD3G CD3G PLD3 PLD3 LOC103088193 LOC103088193 PLD4 PLD4 LOC103075075 LOC103075075 PLD2 PLD2 NCKAP1 NCKAP1 ELMO3 ELMO3 PIK3R1 PIK3R1 GRB2 GRB2 ABI2 ABI2 LOC103075361 LOC103075361 LOC103090744 LOC103090744 HSP90AA1 HSP90AA1 CRK CRK MAPK3 MAPK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLA2G685/88 kDa calcium-independent phospholipase A2. (805 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
MYO1DUnconventional myosin-Id; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (955 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
ACTBActin, cytoplasmic 1. (375 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (742 aa)
NCKIPSDNCK-interacting protein with SH3 domain isoform X1. (721 aa)
ELMO2Engulfment and cell motility protein 2 isoform X3. (732 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
MYO10Unconventional myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2076 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
VAV3Guanine nucleotide exchange factor VAV3 isoform X1. (875 aa)
LOC103073174Heat shock cognate 90 kDa protein-like. (634 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (170 aa)
LOC103091002Uncharacterized protein LOC103091002. (315 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
DOCK1Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (1886 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (878 aa)
IGLL5Immunoglobulin lambda-like polypeptide 5. (234 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (559 aa)
LOC103080281Probable protein BRICK1-like. (75 aa)
LOC103079081Uncharacterized protein LOC103079081. (304 aa)
WIPF1WAS/WASL-interacting protein family member 1-like. (495 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
LOC103084661Obscurin-like. (361 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (201 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (387 aa)
MYO1HUnconventional myosin-Ih; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1022 aa)
MYO1GUnconventional myosin-Ig; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
LOC103069874Abl interactor 1-like. (235 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (675 aa)
LOC103070587Tyrosine-protein kinase ABL1-like. (126 aa)
LOC103090824Formin-2-like. (1322 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (505 aa)
WASF3wiskott-Aldrich syndrome protein family member 3. (502 aa)
ACTR3BActin-related protein 3B-like isoform X1; Belongs to the actin family. (418 aa)
ABI1Abl interactor 1-like isoform X1. (379 aa)
PPAPDC1BPhosphatidate phosphatase PPAPDC1B isoform X2. (261 aa)
LOC103082646WAS protein family homolog 1-like. (472 aa)
NCKAP1LNck-associated protein 1-like. (1134 aa)
PPAPDC1APhosphatidate phosphatase PPAPDC1A isoform X1. (271 aa)
MYO1AUnconventional myosin-Ia isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
LIMK1LIM domain kinase 1. (647 aa)
WIPF3WAS/WASL-interacting protein family member 3. (416 aa)
LOC103076856Cofilin-1-like; Belongs to the actin-binding proteins ADF family. (262 aa)
MYO1BLOW QUALITY PROTEIN: unconventional myosin-Ib; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1141 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
PLD1Phospholipase. (1074 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1003 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
CFL2Cofilin-2 isoform X1; Belongs to the actin-binding proteins ADF family. (166 aa)
LOC103069126Actin-related protein 3-like isoform X1; Belongs to the actin family. (418 aa)
WIPF2WAS/WASL-interacting protein family member 2 isoform X1. (440 aa)
LOC103074911Heat shock cognate 90 kDa protein-like. (518 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
FMN1Formin-1 isoform X1. (1420 aa)
PLD5LOW QUALITY PROTEIN: inactive phospholipase D5. (536 aa)
MYO5CUnconventional myosin-Vc; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1742 aa)
MYO5AUnconventional myosin-Va; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1653 aa)
CFL1Cofilin-1; Belongs to the actin-binding proteins ADF family. (166 aa)
PAK1Non-specific serine/threonine protein kinase. (563 aa)
VAV1Proto-oncogene vav isoform X1. (844 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (535 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
DSTNDestrin; Belongs to the actin-binding proteins ADF family. (165 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. (493 aa)
WASF2wiskott-Aldrich syndrome protein family member 2 isoform X1. (498 aa)
NF2LOW QUALITY PROTEIN: merlin. (592 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
LOC103088736Low affinity immunoglobulin gamma Fc region receptor II-like. (317 aa)
LOC103068717Low affinity immunoglobulin gamma Fc region receptor III-like. (224 aa)
HSP90AB1Heat shock protein HSP 90-beta isoform X1. (724 aa)
NCK1Cytoplasmic protein. (377 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (182 aa)
PLD3Phospholipase D3 isoform X1. (490 aa)
LOC103088193Low affinity immunoglobulin gamma Fc region receptor II-like. (278 aa)
PLD4Phospholipase D4. (517 aa)
LOC103075075Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like. (149 aa)
PLD2Phospholipase. (933 aa)
NCKAP1Nck-associated protein 1. (1126 aa)
ELMO3Engulfment and cell motility protein 3 isoform X1. (720 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
ABI2Abl interactor 2 isoform X1. (540 aa)
LOC103075361Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like. (149 aa)
LOC103090744Uncharacterized protein LOC103090744. (317 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (732 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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