STRINGSTRING
ACTR2 ACTR2 MYO1B MYO1B LOC103076856 LOC103076856 WIPF3 WIPF3 LIMK1 LIMK1 LOC103090824 LOC103090824 MYO1A MYO1A NCKAP1L NCKAP1L LOC103082646 LOC103082646 ABI1 ABI1 ACTR3B ACTR3B WASF3 WASF3 MYO1G MYO1G CYFIP2 CYFIP2 LOC103069874 LOC103069874 LOC103070587 LOC103070587 MYO1D MYO1D MAPK3 MAPK3 CRK CRK HSP90AA1 HSP90AA1 LOC103090744 LOC103090744 LOC103075361 LOC103075361 ABI2 ABI2 GRB2 GRB2 ELMO3 ELMO3 NCKAP1 NCKAP1 LOC103075075 LOC103075075 LOC103088193 LOC103088193 CD3G CD3G NCK1 NCK1 WASL WASL HSP90AB1 HSP90AB1 LOC103068717 LOC103068717 LOC103088736 LOC103088736 ACTL8 ACTL8 NF2 NF2 WASF2 WASF2 CDC42 CDC42 DSTN DSTN ACTG1 ACTG1 BAIAP2 BAIAP2 VAV1 VAV1 PAK1 PAK1 CFL1 CFL1 MYO5A MYO5A MYO5C MYO5C FMN1 FMN1 CYFIP1 CYFIP1 LOC103074911 LOC103074911 WIPF2 WIPF2 LOC103069126 LOC103069126 CFL2 CFL2 PTK2 PTK2 SYK SYK ACTB ACTB ELMO1 ELMO1 NCKIPSD NCKIPSD ELMO2 ELMO2 ARPC1B ARPC1B MYO10 MYO10 ARPC5 ARPC5 VAV3 VAV3 LOC103073174 LOC103073174 MYO1H MYO1H ARPC1A ARPC1A RAC1 RAC1 WAS WAS MAPK1 MAPK1 LOC103084661 LOC103084661 ARPC3 ARPC3 ARPC2 ARPC2 WIPF1 WIPF1 LOC103079081 LOC103079081 LOC103080281 LOC103080281 WASF1 WASF1 ARPC5L ARPC5L IGLL5 IGLL5 VAV2 VAV2 DOCK1 DOCK1 ABL1 ABL1 ARPC4 ARPC4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
MYO1BLOW QUALITY PROTEIN: unconventional myosin-Ib; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1141 aa)
LOC103076856Cofilin-1-like; Belongs to the actin-binding proteins ADF family. (262 aa)
WIPF3WAS/WASL-interacting protein family member 3. (416 aa)
LIMK1LIM domain kinase 1. (647 aa)
LOC103090824Formin-2-like. (1322 aa)
MYO1AUnconventional myosin-Ia isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
NCKAP1LNck-associated protein 1-like. (1134 aa)
LOC103082646WAS protein family homolog 1-like. (472 aa)
ABI1Abl interactor 1-like isoform X1. (379 aa)
ACTR3BActin-related protein 3B-like isoform X1; Belongs to the actin family. (418 aa)
WASF3wiskott-Aldrich syndrome protein family member 3. (502 aa)
MYO1GUnconventional myosin-Ig; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1013 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
LOC103069874Abl interactor 1-like. (235 aa)
LOC103070587Tyrosine-protein kinase ABL1-like. (126 aa)
MYO1DUnconventional myosin-Id; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (955 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
CRKAdapter molecule crk isoform X1. (304 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (732 aa)
LOC103090744Uncharacterized protein LOC103090744. (317 aa)
LOC103075361Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like. (149 aa)
ABI2Abl interactor 2 isoform X1. (540 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
ELMO3Engulfment and cell motility protein 3 isoform X1. (720 aa)
NCKAP1Nck-associated protein 1. (1126 aa)
LOC103075075Putative V-set and immunoglobulin domain-containing-like protein IGHV4OR15-8-like. (149 aa)
LOC103088193Low affinity immunoglobulin gamma Fc region receptor II-like. (278 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (182 aa)
NCK1Cytoplasmic protein. (377 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (505 aa)
HSP90AB1Heat shock protein HSP 90-beta isoform X1. (724 aa)
LOC103068717Low affinity immunoglobulin gamma Fc region receptor III-like. (224 aa)
LOC103088736Low affinity immunoglobulin gamma Fc region receptor II-like. (317 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
NF2LOW QUALITY PROTEIN: merlin. (592 aa)
WASF2wiskott-Aldrich syndrome protein family member 2 isoform X1. (498 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
DSTNDestrin; Belongs to the actin-binding proteins ADF family. (165 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
BAIAP2Brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X1. (535 aa)
VAV1Proto-oncogene vav isoform X1. (844 aa)
PAK1Non-specific serine/threonine protein kinase. (563 aa)
CFL1Cofilin-1; Belongs to the actin-binding proteins ADF family. (166 aa)
MYO5AUnconventional myosin-Va; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1653 aa)
MYO5CUnconventional myosin-Vc; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1742 aa)
FMN1Formin-1 isoform X1. (1420 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
LOC103074911Heat shock cognate 90 kDa protein-like. (518 aa)
WIPF2WAS/WASL-interacting protein family member 2 isoform X1. (440 aa)
LOC103069126Actin-related protein 3-like isoform X1; Belongs to the actin family. (418 aa)
CFL2Cofilin-2 isoform X1; Belongs to the actin-binding proteins ADF family. (166 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1003 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
ACTBActin, cytoplasmic 1. (375 aa)
ELMO1Engulfment and cell motility protein 1 isoform X1. (742 aa)
NCKIPSDNCK-interacting protein with SH3 domain isoform X1. (721 aa)
ELMO2Engulfment and cell motility protein 2 isoform X3. (732 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
MYO10Unconventional myosin-X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2076 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
VAV3Guanine nucleotide exchange factor VAV3 isoform X1. (875 aa)
LOC103073174Heat shock cognate 90 kDa protein-like. (634 aa)
MYO1HUnconventional myosin-Ih; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1022 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (387 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (201 aa)
WASwiskott-Aldrich syndrome protein. (502 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
LOC103084661Obscurin-like. (361 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
WIPF1WAS/WASL-interacting protein family member 1-like. (495 aa)
LOC103079081Uncharacterized protein LOC103079081. (304 aa)
LOC103080281Probable protein BRICK1-like. (75 aa)
WASF1wiskott-Aldrich syndrome protein family member 1. (559 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
IGLL5Immunoglobulin lambda-like polypeptide 5. (234 aa)
VAV2Guanine nucleotide exchange factor VAV2 isoform X1. (878 aa)
DOCK1Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (1886 aa)
ABL1Tyrosine-protein kinase. (1006 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (170 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.