STRINGSTRING
LOC103081970 LOC103081970 LOC103089645 LOC103089645 PHC3 PHC3 MAPK14 MAPK14 MAP4K4 MAP4K4 LOC103083996 LOC103083996 CDK4 CDK4 EZH2 EZH2 RBBP4 RBBP4 LOC103069061 LOC103069061 LOC103068403 LOC103068403 LOC103068676 LOC103068676 LOC103076354 LOC103076354 LOC103077708 LOC103077708 LOC103079101 LOC103079101 LOC103081667 LOC103081667 LOC103082925 LOC103082925 LOC103088169 LOC103088169 MDM4 MDM4 MAPKAPK2 MAPKAPK2 PHC1 PHC1 LOC103076894 LOC103076894 LOC103080928 LOC103080928 MAPK8 MAPK8 LOC103079983 LOC103079983 TXN TXN EZH1 EZH1 LOC103081641 LOC103081641 MAP2K3 MAP2K3 MAPKAPK5 MAPKAPK5 EED EED SCML1 SCML1 MAPK1 MAPK1 LOC103071163 LOC103071163 LOC103085965 LOC103085965 LOC103077443 LOC103077443 LOC103089763 LOC103089763 LOC103088445 LOC103088445 LOC103081931 LOC103081931 LOC103080666 LOC103080666 LOC103076624 LOC103076624 LOC103074679 LOC103074679 FOSL2 FOSL2 LOC103086798 LOC103086798 NPTX2 NPTX2 TXNDC8 TXNDC8 LOC103070340 LOC103070340 LOC103071706 LOC103071706 LOC103071989 LOC103071989 LOC103073911 LOC103073911 LOC103074978 LOC103074978 SUZ12 SUZ12 RNF2 RNF2 CBX7 CBX7 MAPKAPK3 MAPKAPK3 MAPK11 MAPK11 TNRC6B TNRC6B MAPK3 MAPK3 LOC103080676 LOC103080676 CDKN2A CDKN2A LOC103074048 LOC103074048 SCMH1 SCMH1 NPTXR NPTXR CBX6 CBX6 SCML2 SCML2 BMI1 BMI1 RBBP7 RBBP7 CDKN2B CDKN2B MAP2K4 MAP2K4 NME8 NME8 LOC103072956 LOC103072956 LOC103090400 LOC103090400 LOC103077995 LOC103077995 LOC103077539 LOC103077539 TP53 TP53 MINK1 MINK1 MAP3K6 MAP3K6 MAP2K7 MAP2K7 TXNDC2 TXNDC2 FOS FOS CDK6 CDK6 CDKN2D CDKN2D CDKN2C CDKN2C CBX2 CBX2 JUN JUN RING1 RING1 NPTX1 NPTX1 CBX8 CBX8 NME9 NME9 CBX4 CBX4 LOC103079884 LOC103079884 LOC103081255 LOC103081255 NRK NRK TNIK TNIK LOC103080427 LOC103080427 LOC103081704 LOC103081704 MAPK9 MAPK9 MAPK10 MAPK10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103081970Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC103089645Histone H2A; Belongs to the histone H2A family. (128 aa)
PHC3Polyhomeotic-like protein 3 isoform X1. (996 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4 isoform X1. (1264 aa)
LOC103083996Sex comb on midleg-like protein 2-like. (703 aa)
CDK4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X1. (751 aa)
RBBP4Histone-binding protein RBBP4 isoform X1. (425 aa)
LOC103069061Mitogen-activated protein kinase kinase kinase 5-like. (127 aa)
LOC103068403Histone H2B type W-T-like; Belongs to the histone H2B family. (184 aa)
LOC103068676Histone H2B type W-T-like; Belongs to the histone H2B family. (177 aa)
LOC103076354Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC103077708Histone H3; Belongs to the histone H3 family. (136 aa)
LOC103079101Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103081667Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC103082925Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103088169Histone H2B; Belongs to the histone H2B family. (127 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (491 aa)
MAPKAPK2MAP kinase-activated protein kinase 2; Belongs to the protein kinase superfamily. (388 aa)
PHC1Polyhomeotic-like protein 1 isoform X1. (1027 aa)
LOC103076894Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103080928Histone H2A; Belongs to the histone H2A family. (130 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
LOC103079983Histone H2A; Belongs to the histone H2A family. (128 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
EZH1Histone-lysine N-methyltransferase EZH1. (747 aa)
LOC103081641LOW QUALITY PROTEIN: dual specificity mitogen-activated protein kinase kinase 6-like; Belongs to the protein kinase superfamily. (394 aa)
MAP2K3Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
MAPKAPK5MAP kinase-activated protein kinase 5 isoform X1. (473 aa)
EEDPolycomb protein EED isoform X1. (466 aa)
SCML1Sex comb on midleg-like protein 1. (338 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
LOC103071163Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103085965Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103077443Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103089763Uncharacterized protein LOC103089763. (411 aa)
LOC103088445Histone H2A; Belongs to the histone H2A family. (117 aa)
LOC103081931Histone H3; Belongs to the histone H3 family. (150 aa)
LOC103080666Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103076624Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103074679Histone H2B; Belongs to the histone H2B family. (127 aa)
FOSL2Fos-related antigen 2 isoform X1. (327 aa)
LOC103086798Histone H2B; Belongs to the histone H2B family. (126 aa)
NPTX2Neuronal pentraxin-2. (431 aa)
TXNDC8Thioredoxin; Belongs to the thioredoxin family. (105 aa)
LOC103070340Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103071706Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103071989Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103073911Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103074978Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
SUZ12Polycomb protein SUZ12. (739 aa)
RNF2E3 ubiquitin-protein ligase RING2 isoform X1. (336 aa)
CBX7Chromobox protein homolog 7. (251 aa)
MAPKAPK3MAP kinase-activated protein kinase 3 isoform X1; Belongs to the protein kinase superfamily. (384 aa)
MAPK11Mitogen-activated protein kinase. (350 aa)
TNRC6BTrinucleotide repeat-containing gene 6B protein isoform X1. (1831 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
LOC103080676Histone H2A; Belongs to the histone H2A family. (129 aa)
CDKN2ACyclin-dependent kinase inhibitor 2A, isoforms 1/2/3. (152 aa)
LOC103074048Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (134 aa)
SCMH1Polycomb protein SCMH1 isoform X1. (661 aa)
NPTXRNeuronal pentraxin receptor. (643 aa)
CBX6Chromobox protein homolog 6. (415 aa)
SCML2Sex comb on midleg-like protein 2-like. (713 aa)
BMI1Polycomb complex protein BMI-1. (326 aa)
RBBP7Histone-binding protein RBBP7 isoform X1. (469 aa)
CDKN2BCyclin-dependent kinase 4 inhibitor B. (131 aa)
MAP2K4Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (410 aa)
NME8Thioredoxin domain-containing protein 3. (425 aa)
LOC103072956Uncharacterized protein LOC103072956. (225 aa)
LOC103090400Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103077995Thioredoxin reductase. (317 aa)
LOC103077539Thioredoxin reductase. (319 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa)
MINK1Misshapen-like kinase 1. (1258 aa)
MAP3K6Mitogen-activated protein kinase kinase kinase 6. (1301 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (435 aa)
TXNDC2Thioredoxin domain-containing protein 2. (485 aa)
FOSProto-oncogene c-Fos isoform X1. (380 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
CDKN2DCyclin-dependent kinase 4 inhibitor D. (166 aa)
CDKN2CCyclin-dependent kinase 4 inhibitor C. (168 aa)
CBX2Chromobox protein homolog 2. (530 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (337 aa)
RING1E3 ubiquitin-protein ligase RING1. (406 aa)
NPTX1Neuronal pentraxin-1. (432 aa)
CBX8Chromobox protein homolog 8. (367 aa)
NME9Thioredoxin domain-containing protein 6; Belongs to the NDK family. (339 aa)
CBX4E3 SUMO-protein ligase CBX4. (927 aa)
LOC103079884Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103081255Histone H2B; Belongs to the histone H2B family. (142 aa)
NRKNik-related protein kinase. (1582 aa)
TNIKTraf2 and NCK-interacting protein kinase isoform X1. (1360 aa)
LOC103080427Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103081704Histone H2B; Belongs to the histone H2B family. (126 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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