STRINGSTRING
LOC103072206 LOC103072206 LOC103088445 LOC103088445 LOC103082391 LOC103082391 LOC103077443 LOC103077443 LOC103085965 LOC103085965 ATM ATM HMGA2 HMGA2 LOC103079983 LOC103079983 NBN NBN TINF2 TINF2 POT1 POT1 LOC103071163 LOC103071163 LOC103070340 LOC103070340 LOC103071706 LOC103071706 TERF2 TERF2 LOC103071989 LOC103071989 LOC103073911 LOC103073911 MRE11A MRE11A LOC103074978 LOC103074978 CABIN1 CABIN1 TERF1 TERF1 CDK3 CDK3 LOC103080676 LOC103080676 CCNE2 CCNE2 ASF1A ASF1A SRCAP SRCAP LOC103074048 LOC103074048 LOC103068676 LOC103068676 CCNE1 CCNE1 LOC103076354 LOC103076354 LOC103079101 LOC103079101 LOC103081667 LOC103081667 LOC103082925 LOC103082925 LOC103088169 LOC103088169 ASF1B ASF1B CDKN1B CDKN1B LOC103076894 LOC103076894 LOC103080928 LOC103080928 LOC103086798 LOC103086798 LOC103074679 LOC103074679 LOC103076624 LOC103076624 LOC103077983 LOC103077983 LOC103079386 LOC103079386 LOC103080666 LOC103080666 LOC103078543 LOC103078543 UBN1 UBN1 ACD ACD LOC103090400 LOC103090400 TP53 TP53 LOC103078197 LOC103078197 LOC103074230 LOC103074230 LMNB2 LMNB2 HMGA1 HMGA1 RAD50 RAD50 KAT5 KAT5 EP400 EP400 TERF2IP TERF2IP LOC103079884 LOC103079884 LOC103081255 LOC103081255 CCNA2 CCNA2 LMNB1 LMNB1 LOC103080427 LOC103080427 LOC103081704 LOC103081704 LOC103081970 LOC103081970 LOC103089645 LOC103089645 CCNA1 CCNA1 CDKN1C CDKN1C CDKN1A CDKN1A CDK2 CDK2 LOC103068403 LOC103068403
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC103072206Histone H1.0-like. (194 aa)
LOC103088445Histone H2A; Belongs to the histone H2A family. (117 aa)
LOC103082391Histone H1.1-like. (217 aa)
LOC103077443Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103085965Histone H2B; Belongs to the histone H2B family. (126 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3058 aa)
HMGA2High mobility group protein HMGI-C. (109 aa)
LOC103079983Histone H2A; Belongs to the histone H2A family. (128 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (749 aa)
TINF2TERF1-interacting nuclear factor 2. (453 aa)
POT1Protection of telomeres protein 1. (785 aa)
LOC103071163Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103070340Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103071706Histone H2A; Belongs to the histone H2A family. (130 aa)
TERF2Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (539 aa)
LOC103071989Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103073911Histone H2B; Belongs to the histone H2B family. (126 aa)
MRE11ADouble-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa)
LOC103074978Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
CABIN1Calcineurin-binding protein cabin-1. (2221 aa)
TERF1Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (437 aa)
CDK3Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
LOC103080676Histone H2A; Belongs to the histone H2A family. (129 aa)
CCNE2G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa)
ASF1AHistone chaperone ASF1A. (204 aa)
SRCAPHelicase SRCAP-like. (3241 aa)
LOC103074048Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (134 aa)
LOC103068676Histone H2B type W-T-like; Belongs to the histone H2B family. (177 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa)
LOC103076354Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC103079101Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103081667Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC103082925Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103088169Histone H2B; Belongs to the histone H2B family. (127 aa)
ASF1BHistone chaperone ASF1B. (202 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (198 aa)
LOC103076894Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103080928Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103086798Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103074679Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC103076624Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103077983Histone H1.4-like. (210 aa)
LOC103079386Histone H1t-like. (212 aa)
LOC103080666Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103078543Histone H1.4-like. (219 aa)
UBN1Ubinuclein-1 isoform X1. (1134 aa)
ACDAdrenocortical dysplasia protein homolog. (454 aa)
LOC103090400Histone H2B; Belongs to the histone H2B family. (126 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa)
LOC103078197Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (973 aa)
LOC103074230Histone chaperone ASF1A-like. (129 aa)
LMNB2lamin-B2; Belongs to the intermediate filament family. (634 aa)
HMGA1High mobility group protein HMG-I/HMG-Y isoform X1. (107 aa)
RAD50DNA repair protein RAD50 isoform X1. (1312 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
EP400E1A-binding protein p400. (3065 aa)
TERF2IPTelomeric repeat-binding factor 2-interacting protein 1. (399 aa)
LOC103079884Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103081255Histone H2B; Belongs to the histone H2B family. (142 aa)
CCNA2cyclin-A2; Belongs to the cyclin family. (432 aa)
LMNB1lamin-B1; Belongs to the intermediate filament family. (586 aa)
LOC103080427Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103081704Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103081970Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC103089645Histone H2A; Belongs to the histone H2A family. (128 aa)
CCNA1cyclin-A1; Belongs to the cyclin family. (421 aa)
CDKN1CCyclin-dependent kinase inhibitor 1C. (257 aa)
CDKN1ACyclin-dependent kinase inhibitor 1 isoform X1. (164 aa)
CDK2Cyclin-dependent kinase 2 isoform X1; Belongs to the protein kinase superfamily. (346 aa)
LOC103068403Histone H2B type W-T-like; Belongs to the histone H2B family. (184 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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