61 items (Lipotes vexillifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	PPP4R4	Serine/threonine-protein phosphatase 4 regulatory subunit 4. (872 aa)
	MAP3K8	Mitogen-activated protein kinase kinase kinase 8. (468 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	LCK	Tyrosine-protein kinase. (520 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	CD4	T-cell surface glycoprotein CD4. (454 aa)
	RICTOR	Rapamycin-insensitive companion of mTOR-like isoform X1. (1580 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1206 aa)
	PPP2R1B	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1. (644 aa)
	PAK3	Serine/threonine-protein kinase PAK 3 isoform X1. (579 aa)
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
	PAK2	Non-specific serine/threonine protein kinase. (523 aa)
	LYN	Tyrosine-protein kinase. (516 aa)
	PPP2R5B	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	PAK1	Non-specific serine/threonine protein kinase. (563 aa)
	VAV1	Proto-oncogene vav isoform X1. (844 aa)
	PIK3R2	Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
	CDC42	Cell division control protein 42 homolog isoform X1. (191 aa)
	LOC103087297	HLA class II histocompatibility antigen, DRB1-4 beta chain-like. (266 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	CD276	CD276 antigen isoform X1. (535 aa)
	CSK	Tyrosine-protein kinase. (450 aa)
	SRC	Tyrosine-protein kinase. (548 aa)
	PDCD1LG2	Programmed cell death 1 ligand 2. (264 aa)
	PIK3R1	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
	ICOS	Inducible T-cell costimulator. (318 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (959 aa)
	KIAA1468	lisH domain and HEAT repeat-containing protein KIAA1468 homolog. (1217 aa)
	PPP2R5C	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (524 aa)
	CD247	T-cell surface glycoprotein CD3 zeta chain. (152 aa)
	LOC103082213	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like isoform X1. (589 aa)
	PPP2R5D	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (602 aa)
	CD3G	T-cell surface glycoprotein CD3 gamma chain. (182 aa)
	LOC103087567	HLA class II histocompatibility antigen, DR alpha chain-like; Belongs to the MHC class II family. (253 aa)
	PPP4R1	Serine/threonine-protein phosphatase 4 regulatory subunit 1. (949 aa)
	PPP2R5E	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (467 aa)
	THEM4	Acyl-coenzyme A thioesterase THEM4. (239 aa)
	YES1	Tyrosine-protein kinase. (541 aa)
	CD274	Programmed cell death 1 ligand 1. (289 aa)
	CD3D	T-cell surface glycoprotein CD3 delta chain isoform X1. (171 aa)
	CTLA4	Cytotoxic T-lymphocyte protein 4 isoform X1. (223 aa)
	GRAP2	GRB2-related adapter protein 2. (317 aa)
	CD3E	T-cell surface glycoprotein CD3 epsilon chain. (197 aa)
	FNBP4	Formin-binding protein 4. (1011 aa)
	PDPK1	3-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
	PRR5	Proline-rich protein 5. (388 aa)
	CD28	T-cell-specific surface glycoprotein CD28. (265 aa)
	ICOSLG	ICOS ligand. (341 aa)
	LOC103087452	DLA class II histocompatibility antigen, DR-1 beta chain-like. (269 aa)
	PIK3R3	LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	CD86	T-lymphocyte activation antigen CD86 isoform X1. (328 aa)
	LOC103079551	Uncharacterized protein LOC103079551. (276 aa)
	PPP2R5A	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (469 aa)
	LOC103086796	SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like isoform X1; Belongs to the MHC class II family. (255 aa)
	RAC1	Ras-related C3 botulinum toxin substrate 1 isoform X1. (201 aa)
	LOC103073818	Programmed cell death protein 1-like. (262 aa)
	CD80	T-lymphocyte activation antigen CD80 isoform X1. (234 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD247	CD274	A0A340X9F5	A0A340X5J4	T-cell surface glycoprotein CD3 zeta chain.	Programmed cell death 1 ligand 1.	0.567
CD247	CD28	A0A340X9F5	A0A340X0W1	T-cell surface glycoprotein CD3 zeta chain.	T-cell-specific surface glycoprotein CD28.	0.492
CD247	CD3D	A0A340X9F5	A0A340X4Y1	T-cell surface glycoprotein CD3 zeta chain.	T-cell surface glycoprotein CD3 delta chain isoform X1.	0.998
CD247	CD3E	A0A340X9F5	A0A340X4A2	T-cell surface glycoprotein CD3 zeta chain.	T-cell surface glycoprotein CD3 epsilon chain.	0.999
CD247	CD3G	A0A340X9F5	A0A340XBI8	T-cell surface glycoprotein CD3 zeta chain.	T-cell surface glycoprotein CD3 gamma chain.	0.999
CD247	CD4	A0A340X9F5	A0A340Y8J8	T-cell surface glycoprotein CD3 zeta chain.	T-cell surface glycoprotein CD4.	0.458
CD247	CSK	A0A340X9F5	A0A340WGT5	T-cell surface glycoprotein CD3 zeta chain.	Tyrosine-protein kinase.	0.649
CD247	FYN	A0A340X9F5	A0A340WT33	T-cell surface glycoprotein CD3 zeta chain.	Tyrosine-protein kinase.	0.953
CD247	GRAP2	A0A340X9F5	A0A340X4H9	T-cell surface glycoprotein CD3 zeta chain.	GRB2-related adapter protein 2.	0.652
CD247	GRB2	A0A340X9F5	A0A340X5P7	T-cell surface glycoprotein CD3 zeta chain.	Growth factor receptor-bound protein 2 isoform X1.	0.531
CD247	ICOS	A0A340X9F5	A0A340X7A5	T-cell surface glycoprotein CD3 zeta chain.	Inducible T-cell costimulator.	0.418
CD247	LCK	A0A340X9F5	A0A340YBD8	T-cell surface glycoprotein CD3 zeta chain.	Tyrosine-protein kinase.	0.772
CD247	LOC103073818	A0A340X9F5	A0A340WKT3	T-cell surface glycoprotein CD3 zeta chain.	Programmed cell death protein 1-like.	0.633
CD247	LOC103086796	A0A340X9F5	A0A340WR59	T-cell surface glycoprotein CD3 zeta chain.	SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like isoform X1; Belongs to the MHC class II family.	0.955
CD247	LOC103087297	A0A340X9F5	A0A340XHK0	T-cell surface glycoprotein CD3 zeta chain.	HLA class II histocompatibility antigen, DRB1-4 beta chain-like.	0.934
CD247	LOC103087452	A0A340X9F5	A0A340WYS7	T-cell surface glycoprotein CD3 zeta chain.	DLA class II histocompatibility antigen, DR-1 beta chain-like.	0.934
CD247	LOC103087567	A0A340X9F5	A0A340XDM7	T-cell surface glycoprotein CD3 zeta chain.	HLA class II histocompatibility antigen, DR alpha chain-like; Belongs to the MHC class II family.	0.946
CD247	LYN	A0A340X9F5	A0A340XV93	T-cell surface glycoprotein CD3 zeta chain.	Tyrosine-protein kinase.	0.515
CD247	PDCD1LG2	A0A340X9F5	A0A340X676	T-cell surface glycoprotein CD3 zeta chain.	Programmed cell death 1 ligand 2.	0.581
CD247	PIK3R1	A0A340X9F5	A0A340X6G2	T-cell surface glycoprotein CD3 zeta chain.	Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.	0.524