STRINGSTRING
ACTB ACTB ACTR2 ACTR2 FNDC3A FNDC3A EFNB2 EFNB2 PTK2 PTK2 FNDC3B FNDC3B LOC103076856 LOC103076856 ARPC1A ARPC1A RAC1 RAC1 LOC103082455 LOC103082455 ARPC3 ARPC3 ARPC2 ARPC2 ARPC5L ARPC5L ARPC4 ARPC4 SDC2 SDC2 LIMK2 LIMK2 GRIN2B GRIN2B EPHB1 EPHB1 ROCK2 ROCK2 LOC103090824 LOC103090824 WASL WASL EFNB1 EFNB1 ACTR3B ACTR3B EPHB3 EPHB3 ITSN1 ITSN1 EPHB4 EPHB4 EPHB6 EPHB6 HRAS HRAS EFNB3 EFNB3 ARHGEF28 ARHGEF28 ACTL8 ACTL8 GRIN1 GRIN1 EPHB2 EPHB2 CDC42 CDC42 DSTN DSTN ACTG1 ACTG1 PAK1 PAK1 CFL1 CFL1 FMN1 FMN1 LOC103069126 LOC103069126 RHOA RHOA CFL2 CFL2 ARPC1B ARPC1B TIAM1 TIAM1 RASA1 RASA1 ARPC5 ARPC5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACTBActin, cytoplasmic 1. (375 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
EFNB2ephrin-B2; Belongs to the ephrin family. (333 aa)
PTK2Focal adhesion kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1003 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
LOC103076856Cofilin-1-like; Belongs to the actin-binding proteins ADF family. (262 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (387 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (201 aa)
LOC103082455Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (170 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (201 aa)
LIMK2LIM domain kinase 2 isoform X1. (638 aa)
GRIN2BGlutamate receptor ionotropic, NMDA 2B. (1496 aa)
EPHB1Ephrin type-B receptor 1. (984 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1389 aa)
LOC103090824Formin-2-like. (1322 aa)
WASLNeural Wiskott-Aldrich syndrome protein. (505 aa)
EFNB1ephrin-B1; Belongs to the ephrin family. (346 aa)
ACTR3BActin-related protein 3B-like isoform X1; Belongs to the actin family. (418 aa)
EPHB3Ephrin type-B receptor 3. (1005 aa)
ITSN1Intersectin-1-like. (616 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
EPHB6Ephrin type-B receptor 6. (1011 aa)
HRASGTPase HRas isoform X1. (189 aa)
EFNB3LOW QUALITY PROTEIN: ephrin-B3; Belongs to the ephrin family. (356 aa)
ARHGEF28Rho guanine nucleotide exchange factor 28. (1390 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (365 aa)
GRIN1Glutamate receptor ionotropic, NMDA 1 isoform X1. (959 aa)
EPHB2Ephrin type-B receptor 2 isoform X1. (964 aa)
CDC42Cell division control protein 42 homolog isoform X1. (191 aa)
DSTNDestrin; Belongs to the actin-binding proteins ADF family. (165 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
PAK1Non-specific serine/threonine protein kinase. (563 aa)
CFL1Cofilin-1; Belongs to the actin-binding proteins ADF family. (166 aa)
FMN1Formin-1 isoform X1. (1420 aa)
LOC103069126Actin-related protein 3-like isoform X1; Belongs to the actin family. (418 aa)
RHOATransforming protein RhoA isoform X1. (221 aa)
CFL2Cofilin-2 isoform X1; Belongs to the actin-binding proteins ADF family. (166 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (372 aa)
TIAM1T-lymphoma invasion and metastasis-inducing protein 1 isoform X1. (1592 aa)
RASA1Ras GTPase-activating protein 1. (1040 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (154 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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