STRINGSTRING
JAK2 JAK2 PTPN6 PTPN6 IL2RG IL2RG LCK LCK IL2RA IL2RA PIK3CA PIK3CA PIK3CB PIK3CB PTK2B PTK2B LOC103069117 LOC103069117 GAB1 GAB1 IL15RA IL15RA INPPL1 INPPL1 STAT4 STAT4 IL2 IL2 IL15 IL15 IL5 IL5 CSF2 CSF2 IL3 IL3 CSF2RA CSF2RA IL9 IL9 IL3RA IL3RA JAK1 JAK1 PIK3R2 PIK3R2 JAK3 JAK3 SHC1 SHC1 GAB2 GAB2 PIK3R1 PIK3R1 GRB2 GRB2 LOC103084127 LOC103084127 CSF2RB CSF2RB SAMD5 SAMD5 IL9R IL9R SAMSN1 SAMSN1 IL2RB IL2RB SASH1 SASH1 LOC103069812 LOC103069812 PIK3CD PIK3CD SASH3 SASH3 IL21R IL21R PIK3R3 PIK3R3 LGALS9 LGALS9 IL5RA IL5RA STAT3 STAT3 STAT5A STAT5A SOS1 SOS1 STAT5B STAT5B HAVCR2 HAVCR2 SYK SYK LOC103087942 LOC103087942 SOS2 SOS2 INPP5D INPP5D
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JAK2Tyrosine-protein kinase. (1132 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
IL2RGCytokine receptor common subunit gamma. (381 aa)
LCKTyrosine-protein kinase. (520 aa)
IL2RAInterleukin-2 receptor subunit alpha. (277 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
LOC103069117LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-like. (721 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (723 aa)
IL15RAInterleukin-15 receptor subunit alpha. (307 aa)
INPPL1LOW QUALITY PROTEIN: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1264 aa)
STAT4Signal transducer and activator of transcription. (748 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (180 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
IL3Interleukin-3. (144 aa)
CSF2RAGranulocyte-macrophage colony-stimulating factor receptor subunit alpha. (429 aa)
IL9Interleukin-9. (141 aa)
IL3RAInterleukin-3 receptor subunit alpha. (385 aa)
JAK1Tyrosine-protein kinase. (1153 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
JAK3Tyrosine-protein kinase. (1104 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
GAB2GRB2-associated-binding protein 2. (640 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
LOC103084127Interleukin; Belongs to the IL-15/IL-21 family. (146 aa)
CSF2RBCytokine receptor common subunit beta. (896 aa)
SAMD5Sterile alpha motif domain-containing protein 5. (175 aa)
IL9RInterleukin-9 receptor-like. (606 aa)
SAMSN1SAM domain-containing protein SAMSN-1 isoform X1. (438 aa)
IL2RBInterleukin-2 receptor subunit beta. (574 aa)
SASH1SAM and SH3 domain-containing protein 1. (1235 aa)
LOC103069812Uncharacterized protein LOC103069812. (170 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
SASH3SAM and SH3 domain-containing protein 3. (380 aa)
IL21RInterleukin-21 receptor. (540 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
LGALS9Galectin. (355 aa)
IL5RAInterleukin-5 receptor subunit alpha. (565 aa)
STAT3Signal transducer and activator of transcription. (654 aa)
STAT5ASignal transducer and activator of transcription. (794 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
STAT5BSignal transducer and activator of transcription. (792 aa)
HAVCR2Hepatitis A virus cellular receptor 2. (280 aa)
SYKTyrosine-protein kinase SYK isoform X1. (636 aa)
LOC103087942Signal transducer and activator of transcription 5A-like. (237 aa)
SOS2Son of sevenless homolog 2-like. (1272 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1187 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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