STRINGSTRING
CACNG5 CACNG5 ATP2B2 ATP2B2 ATP1B3 ATP1B3 KCNE3 KCNE3 SLC8A1 SLC8A1 KCNE1 KCNE1 TRDN TRDN CACNB2 CACNB2 ORAI1 ORAI1 ATP2A2 ATP2A2 SRI SRI ITPR2 ITPR2 ATP2B4 ATP2B4 KCNE2 KCNE2 KCNJ12 KCNJ12 KCND3 KCND3 ABCC9 ABCC9 TRPC1 TRPC1 SDR42E2 SDR42E2 SCN9A SCN9A MAST2 MAST2 SCN3A SCN3A CORIN CORIN AHCYL1 AHCYL1 STIM2 STIM2 KCNK2 KCNK2 MMEL1 MMEL1 ATP2B1 ATP2B1 SCN7A SCN7A SCN1A SCN1A SCN2A SCN2A LOC103091543 LOC103091543 SCN8A SCN8A ATP1A1 ATP1A1 ORAI3 ORAI3 RYR2 RYR2 KCND1 KCND1 LOC103081664 LOC103081664 LOC103091465 LOC103091465 CACNA2D2 CACNA2D2 ATP2A3 ATP2A3 ATP2A1 ATP2A1 PLN PLN ASPHD1 ASPHD1 ITPR1 ITPR1 NPR2 NPR2 KCNJ4 KCNJ4 PHEX PHEX KCNJ2 KCNJ2 ATP2B3 ATP2B3 SLC8A3 SLC8A3 LOC103090142 LOC103090142 CASQ2 CASQ2 FKBP1B FKBP1B LOC103083779 LOC103083779 ATP1B2 ATP1B2 RANGRF RANGRF NOS1 NOS1 KCNK17 KCNK17 MAST4 MAST4 SLC8A2 SLC8A2 DMPK DMPK SCN2B SCN2B FXYD6 FXYD6 SCN4B SCN4B CACNG7 CACNG7 SCN4A SCN4A CACNG6 CACNG6 KCND2 KCND2 LOC103089871 LOC103089871 KCNK16 KCNK16 ATP1A4 ATP1A4 KCNK12 KCNK12 ATP1B1 ATP1B1 KCNK5 KCNK5 CACNG8 CACNG8 NPR1 NPR1 CALM3 CALM3 ATP1A3 ATP1A3 LOC103076006 LOC103076006 LOC103080780 LOC103080780 LOC103080144 LOC103080144 KCNJ11 KCNJ11 MAST3 MAST3 CASQ1 CASQ1 KCNK7 KCNK7 ATP1A2 ATP1A2 NPPC NPPC SCN3B SCN3B STIM1 STIM1 ITPR3 ITPR3 ASPHD2 ASPHD2 FGF14 FGF14 LOC103087767 LOC103087767 KCNK4 KCNK4 KCNE4 KCNE4 KCNIP4 KCNIP4 RYR3 RYR3 KCNK9 KCNK9 KCNK10 KCNK10 NPPA NPPA NPPB NPPB KCNJ14 KCNJ14 KCNE1L KCNE1L KCNIP1 KCNIP1 NKX2-5 NKX2-5 KCNK15 KCNK15 CLIC2 CLIC2 KCNK1 KCNK1 LOC103078800 LOC103078800 CACNB1 CACNB1 LOC103074541 LOC103074541 KCNQ1 KCNQ1 SCN5A SCN5A LOC103086217 LOC103086217 PRKACA PRKACA MAST1 MAST1 FGF12 FGF12 CACNA2D1 CACNA2D1 ORAI2 ORAI2 TNNI3 TNNI3 SCN11A SCN11A CACNA1C CACNA1C SCN10A SCN10A KCNH2 KCNH2 FAHD2A FAHD2A LOC103069064 LOC103069064 FXYD1 FXYD1 RYR1 RYR1 KCNA5 KCNA5 ASPH ASPH FXYD7 FXYD7 KCNIP3 KCNIP3 LOC103088815 LOC103088815 KCNK3 KCNK3 KCNIP2 KCNIP2 SCN1B SCN1B FXYD3 FXYD3 FXYD5 FXYD5 KCNK6 KCNK6 KCNK18 KCNK18 CALM1 CALM1 KCNK13 KCNK13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CACNG5Voltage-dependent calcium channel gamma-5 subunit. (275 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
KCNE3Potassium voltage-gated channel subfamily E member 3. (99 aa)
SLC8A1Sodium/calcium exchanger 1 isoform X1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (970 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (129 aa)
TRDNTriadin. (702 aa)
CACNB2Voltage-dependent L-type calcium channel subunit beta-2 isoform X1. (651 aa)
ORAI1Calcium release-activated calcium channel protein 1. (303 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1039 aa)
SRISorcin. (198 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2701 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1207 aa)
KCNE2Potassium voltage-gated channel subfamily E member 2. (123 aa)
KCNJ12ATP-sensitive inward rectifier potassium channel 12. (427 aa)
KCND3Potassium voltage-gated channel subfamily D member 3. (283 aa)
ABCC9ATP-binding cassette sub-family C member 9 isoform X1. (1549 aa)
TRPC1Short transient receptor potential channel 1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
SDR42E2Putative short-chain dehydrogenase/reductase family 42E member 2-like. (421 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1987 aa)
MAST2Microtubule-associated serine/threonine-protein kinase 2. (1801 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1999 aa)
CORINLOW QUALITY PROTEIN: atrial natriuretic peptide-converting enzyme. (1102 aa)
AHCYL1Adenosylhomocysteinase. (530 aa)
STIM2Stromal interaction molecule 2 isoform X1. (838 aa)
KCNK2Potassium channel subfamily K member 2-like isoform X2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (427 aa)
MMEL1LOW QUALITY PROTEIN: membrane metallo-endopeptidase-like 1. (841 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1678 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2006 aa)
LOC103091543Vomeronasal type-1 receptor. (102 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1994 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (919 aa)
ORAI3Protein orai-3. (306 aa)
RYR2Ryanodine receptor 2-like. (4986 aa)
KCND1Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (648 aa)
LOC103081664Potassium voltage-gated channel subfamily D member 2-like; Belongs to the potassium channel family. (372 aa)
LOC103091465Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
CACNA2D2Voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1. (1153 aa)
ATP2A3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1001 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1000 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
ASPHD1Aspartate beta-hydroxylase domain-containing protein 1. (367 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1 isoform X1. (2744 aa)
NPR2Guanylate cyclase. (1052 aa)
KCNJ4Inward rectifier potassium channel 4. (445 aa)
PHEXPhosphate-regulating neutral endopeptidase isoform X1. (749 aa)
KCNJ2Inward rectifier potassium channel 2. (427 aa)
ATP2B3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1218 aa)
SLC8A3Sodium/calcium exchanger 3 isoform X2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (304 aa)
LOC103090142Corticotropin-releasing factor receptor 1-like; Belongs to the G-protein coupled receptor 2 family. (240 aa)
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (410 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
LOC103083779Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (261 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (294 aa)
RANGRFRan guanine nucleotide release factor isoform X2. (186 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1427 aa)
KCNK17Potassium channel subfamily K member. (343 aa)
MAST4Microtubule-associated serine/threonine-protein kinase 4 isoform X1. (2605 aa)
SLC8A2Sodium/calcium exchanger 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa)
DMPKMyotonin-protein kinase isoform X1. (630 aa)
SCN2BSodium channel subunit beta-2. (215 aa)
FXYD6FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (143 aa)
SCN4BSodium channel subunit beta-4. (228 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1816 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit. (225 aa)
KCND2Potassium voltage-gated channel subfamily D member 2. (255 aa)
LOC103089871Sulfate/thiosulfate import ATP-binding protein cysA-like. (208 aa)
KCNK16Potassium channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (292 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (994 aa)
KCNK12Potassium channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (411 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
KCNK5Potassium channel subfamily K member 5 isoform X1; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (499 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (448 aa)
NPR1Guanylate cyclase. (1058 aa)
CALM3Calmodulin isoform X2; Belongs to the calmodulin family. (149 aa)
ATP1A3Sodium/potassium-transporting ATPase subunit alpha. (983 aa)
LOC103076006Fibroblast growth factor 11-like; Belongs to the heparin-binding growth factors family. (174 aa)
LOC103080780Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (519 aa)
LOC103080144Sodium/calcium exchanger 3-like; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (595 aa)
KCNJ11ATP-sensitive inward rectifier potassium channel 11 isoform X1. (388 aa)
MAST3Microtubule-associated serine/threonine-protein kinase 3. (1312 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (400 aa)
KCNK7Potassium channel subfamily K member. (307 aa)
ATP1A2Sodium/potassium-transporting ATPase subunit alpha. (1020 aa)
NPPCC-type natriuretic peptide. (126 aa)
SCN3BSodium channel subunit beta-3 isoform X1. (255 aa)
STIM1Stromal interaction molecule 1 isoform X1. (785 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
ASPHD2Aspartate beta-hydroxylase domain-containing protein 2. (368 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
LOC103087767Voltage-dependent calcium channel gamma-6 subunit-like. (85 aa)
KCNK4Potassium channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (401 aa)
KCNE4Potassium voltage-gated channel subfamily E member 4. (170 aa)
KCNIP4Kv channel-interacting protein 4 isoform X1. (233 aa)
RYR3Ryanodine receptor 3. (4869 aa)
KCNK9Potassium channel subfamily K member. (374 aa)
KCNK10Potassium channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (537 aa)
NPPANatriuretic peptides A. (152 aa)
NPPBNatriuretic peptides B. (132 aa)
KCNJ14ATP-sensitive inward rectifier potassium channel 14. (434 aa)
KCNE1LPotassium voltage-gated channel subfamily E member 1-like protein. (145 aa)
KCNIP1Kv channel-interacting protein 1 isoform X2. (213 aa)
NKX2-5Homeobox protein Nkx-2.5. (324 aa)
KCNK15Potassium channel subfamily K member 15; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (332 aa)
CLIC2Chloride intracellular channel protein 2. (247 aa)
KCNK1Potassium channel subfamily K member. (336 aa)
LOC103078800Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (541 aa)
CACNB1LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit beta-1. (678 aa)
LOC103074541LOW QUALITY PROTEIN: calmodulin-like protein 1-like; Belongs to the calmodulin family. (289 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1; Belongs to the potassium channel family. (580 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2020 aa)
LOC103086217Potassium voltage-gated channel subfamily D member 3-like; Belongs to the potassium channel family. (369 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
MAST1Microtubule-associated serine/threonine-protein kinase 1. (1562 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1. (959 aa)
ORAI2Protein orai-2. (268 aa)
TNNI3Troponin I, cardiac muscle. (211 aa)
SCN11ASodium channel protein type 11 subunit alpha. (1442 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2112 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1965 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1198 aa)
FAHD2AFumarylacetoacetate hydrolase domain-containing protein 2A. (314 aa)
LOC103069064Guanylate cyclase. (1015 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (104 aa)
RYR1Ryanodine receptor 1 isoform X2. (5032 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (595 aa)
ASPHAspartyl/asparaginyl beta-hydroxylase. (755 aa)
FXYD7FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (80 aa)
KCNIP3Calsenilin isoform X1. (255 aa)
LOC103088815Neprilysin-like isoform X1. (750 aa)
KCNK3Potassium channel subfamily K member. (402 aa)
KCNIP2Kv channel-interacting protein 2 isoform X1. (285 aa)
SCN1BSodium channel subunit beta-1. (218 aa)
FXYD3FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (88 aa)
FXYD5FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (172 aa)
KCNK6Potassium channel subfamily K member. (322 aa)
KCNK18LOW QUALITY PROTEIN: potassium channel, subfamily K, member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (332 aa)
CALM1Calmodulin isoform X1; Belongs to the calmodulin family. (150 aa)
KCNK13Potassium channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (410 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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