12 items (Lipotes vexillifer) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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gene neighborhood

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Your Input:
	HRAS	GTPase HRas isoform X1. (189 aa)
	NRAS	GTPase NRas. (189 aa)
	CSDE1	Cold shock domain-containing protein E1 isoform X1. (843 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (584 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	FGFR2	Fibroblast growth factor receptor. (839 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	ERAS	GTPase ERas. (233 aa)
	SOS1	Son of sevenless homolog 1. (1333 aa)
	KRAS	GTPase KRas. (188 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	GRB2	A0A340XM96	A0A340X5P7	Cold shock domain-containing protein E1 isoform X1.	Growth factor receptor-bound protein 2 isoform X1.	0.562
CSDE1	SOS1	A0A340XM96	A0A340WF86	Cold shock domain-containing protein E1 isoform X1.	Son of sevenless homolog 1.	0.612
ERAS	GRB2	A0A340WN40	A0A340X5P7	GTPase ERas.	Growth factor receptor-bound protein 2 isoform X1.	0.562
ERAS	SOS1	A0A340WN40	A0A340WF86	GTPase ERas.	Son of sevenless homolog 1.	0.651
FGF1	FGF7	A0A340Y5Y7	A0A340X203	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.498
FGF1	FGFR2	A0A340Y5Y7	A0A340YAX6	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor receptor.	0.997
FGF1	GRB2	A0A340Y5Y7	A0A340X5P7	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Growth factor receptor-bound protein 2 isoform X1.	0.495
FGF1	KRAS	A0A340Y5Y7	A0A340WCQ7	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	GTPase KRas.	0.400
FGF7	FGF1	A0A340X203	A0A340Y5Y7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.498
FGF7	FGF9	A0A340X203	A0A340XWI1	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.410
FGF7	FGFR2	A0A340X203	A0A340YAX6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.991
FGF7	GRB2	A0A340X203	A0A340X5P7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Growth factor receptor-bound protein 2 isoform X1.	0.527
FGF7	KRAS	A0A340X203	A0A340WCQ7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	GTPase KRas.	0.489
FGF9	FGF7	A0A340XWI1	A0A340X203	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.410
FGF9	FGFR2	A0A340XWI1	A0A340YAX6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.989
FGF9	GRB2	A0A340XWI1	A0A340X5P7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Growth factor receptor-bound protein 2 isoform X1.	0.478
FGF9	KRAS	A0A340XWI1	A0A340WCQ7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	GTPase KRas.	0.495
FGFR2	FGF1	A0A340YAX6	A0A340Y5Y7	Fibroblast growth factor receptor.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.997
FGFR2	FGF7	A0A340YAX6	A0A340X203	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.991
FGFR2	FGF9	A0A340YAX6	A0A340XWI1	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.989