STRINGSTRING
FGF1 FGF1 KRAS KRAS SOS1 SOS1 ERAS ERAS GRB2 GRB2 SHC1 SHC1 CSDE1 CSDE1 NRAS NRAS FGF9 FGF9 FGFR3 FGFR3 HRAS HRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa)
KRASGTPase KRas. (188 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
ERASGTPase ERas. (233 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (843 aa)
NRASGTPase NRas. (189 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGFR3Fibroblast growth factor receptor. (804 aa)
HRASGTPase HRas isoform X1. (189 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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