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FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa) | ||||
KRAS | GTPase KRas. (188 aa) | ||||
SOS1 | Son of sevenless homolog 1. (1333 aa) | ||||
ERAS | GTPase ERas. (233 aa) | ||||
GRB2 | Growth factor receptor-bound protein 2 isoform X1. (217 aa) | ||||
SHC1 | SHC-transforming protein 1 isoform X1. (584 aa) | ||||
CSDE1 | Cold shock domain-containing protein E1 isoform X1. (843 aa) | ||||
NRAS | GTPase NRas. (189 aa) | ||||
FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
FGFR3 | Fibroblast growth factor receptor. (804 aa) | ||||
HRAS | GTPase HRas isoform X1. (189 aa) |