node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CSDE1 | GRB2 | A0A340XM96 | A0A340X5P7 | Cold shock domain-containing protein E1 isoform X1. | Growth factor receptor-bound protein 2 isoform X1. | 0.562 |
CSDE1 | PIK3CA | A0A340XM96 | A0A340Y0D6 | Cold shock domain-containing protein E1 isoform X1. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. | 0.639 |
CSDE1 | PTPN11 | A0A340XM96 | A0A340YB65 | Cold shock domain-containing protein E1 isoform X1. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.436 |
CSDE1 | SOS1 | A0A340XM96 | A0A340WF86 | Cold shock domain-containing protein E1 isoform X1. | Son of sevenless homolog 1. | 0.612 |
ERAS | GRB2 | A0A340WN40 | A0A340X5P7 | GTPase ERas. | Growth factor receptor-bound protein 2 isoform X1. | 0.562 |
ERAS | PIK3CA | A0A340WN40 | A0A340Y0D6 | GTPase ERas. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. | 0.697 |
ERAS | PIK3R1 | A0A340WN40 | A0A340X6G2 | GTPase ERas. | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. | 0.470 |
ERAS | PTPN11 | A0A340WN40 | A0A340YB65 | GTPase ERas. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.443 |
ERAS | SOS1 | A0A340WN40 | A0A340WF86 | GTPase ERas. | Son of sevenless homolog 1. | 0.651 |
FGF1 | FGFR3 | A0A340Y5Y7 | A0A340Y2L5 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor receptor. | 0.987 |
FGF1 | FRS2 | A0A340Y5Y7 | A0A340XW80 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor receptor substrate 2. | 0.508 |
FGF1 | GRB2 | A0A340Y5Y7 | A0A340X5P7 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Growth factor receptor-bound protein 2 isoform X1. | 0.495 |
FGF1 | KRAS | A0A340Y5Y7 | A0A340WCQ7 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | GTPase KRas. | 0.400 |
FGF1 | PIK3CA | A0A340Y5Y7 | A0A340Y0D6 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. | 0.420 |
FGF1 | PTPN11 | A0A340Y5Y7 | A0A340YB65 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.456 |
FGF9 | FGFR3 | A0A340XWI1 | A0A340Y2L5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Fibroblast growth factor receptor. | 0.955 |
FGF9 | FRS2 | A0A340XWI1 | A0A340XW80 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Fibroblast growth factor receptor substrate 2. | 0.636 |
FGF9 | GRB2 | A0A340XWI1 | A0A340X5P7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Growth factor receptor-bound protein 2 isoform X1. | 0.478 |
FGF9 | KRAS | A0A340XWI1 | A0A340WCQ7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | GTPase KRas. | 0.495 |
FGF9 | PTPN11 | A0A340XWI1 | A0A340YB65 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.412 |