39 items (Lipotes vexillifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FNDC3A	Fibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
	KL	Klotho. (1012 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	FGF9	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	FRS2	Fibroblast growth factor receptor substrate 2. (508 aa)
	MKNK1	MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (435 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	UBA52	ubiquitin-60S ribosomal protein L40. (128 aa)
	PPP2CB	Serine/threonine-protein phosphatase. (309 aa)
	UBC	polyubiquitin-C. (462 aa)
	LOC103083100	ubiquitin-60S ribosomal protein L40-like. (116 aa)
	KAL1	Anosmin-1-like. (674 aa)
	FGF17	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	LOC103076438	ubiquitin-40S ribosomal protein S27a-like. (155 aa)
	MAPK3	Mitogen-activated protein kinase. (325 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (910 aa)
	LOC103072950	Uncharacterized protein LOC103072950. (442 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	FGF22	LOW QUALITY PROTEIN: fibroblast growth factor 22; Belongs to the heparin-binding growth factors family. (229 aa)
	FGF5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (266 aa)
	FGF3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (232 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	FGFR1	Fibroblast growth factor receptor. (837 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
	FGF23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (244 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	LOC103076597	ubiquitin-40S ribosomal protein S27a-like. (187 aa)
	FGF1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa)
	BRAF	Serine/threonine-protein kinase B-raf. (763 aa)
	FGF4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
	FNDC3B	Fibronectin type III domain-containing protein 3B. (1206 aa)
	SPRY2	Protein sprouty homolog 2 isoform X1. (315 aa)
	MKNK2	MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (463 aa)
	UBB	polyubiquitin-C isoform X1. (305 aa)
	FGF20	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
	SRC	Tyrosine-protein kinase. (548 aa)
	MAPK1	Mitogen-activated protein kinase 1 isoform X1. (263 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRAF	FGFR1	A0A340Y5C2	A0A340YBM5	Serine/threonine-protein kinase B-raf.	Fibroblast growth factor receptor.	0.504
BRAF	GRB2	A0A340Y5C2	A0A340X5P7	Serine/threonine-protein kinase B-raf.	Growth factor receptor-bound protein 2 isoform X1.	0.449
BRAF	MAPK1	A0A340Y5C2	A0A340WNH5	Serine/threonine-protein kinase B-raf.	Mitogen-activated protein kinase 1 isoform X1.	0.855
BRAF	MAPK3	A0A340Y5C2	A0A340WYU9	Serine/threonine-protein kinase B-raf.	Mitogen-activated protein kinase.	0.854
BRAF	PPP2CA	A0A340Y5C2	A0A340XQW3	Serine/threonine-protein kinase B-raf.	Serine/threonine-protein phosphatase.	0.443
BRAF	PPP2CB	A0A340Y5C2	A0A340WJD4	Serine/threonine-protein kinase B-raf.	Serine/threonine-protein phosphatase.	0.443
BRAF	PTPN11	A0A340Y5C2	A0A340YB65	Serine/threonine-protein kinase B-raf.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.514
BRAF	SPRY2	A0A340Y5C2	A0A340XZP8	Serine/threonine-protein kinase B-raf.	Protein sprouty homolog 2 isoform X1.	0.924
BRAF	SRC	A0A340Y5C2	A0A340WDY6	Serine/threonine-protein kinase B-raf.	Tyrosine-protein kinase.	0.533
CBL	FGF1	A0A340X461	A0A340Y5Y7	E3 ubiquitin-protein ligase CBL.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.450
CBL	FGF10	A0A340X461	A0A340XK40	E3 ubiquitin-protein ligase CBL.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.542
CBL	FGF17	A0A340X461	A0A340WUQ4	E3 ubiquitin-protein ligase CBL.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.518
CBL	FGF20	A0A340X461	A0A340XL15	E3 ubiquitin-protein ligase CBL.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.551
CBL	FGF22	A0A340X461	A0A340XGF6	E3 ubiquitin-protein ligase CBL.	LOW QUALITY PROTEIN: fibroblast growth factor 22; Belongs to the heparin-binding growth factors family.	0.542
CBL	FGF23	A0A340X461	A0A340Y7E0	E3 ubiquitin-protein ligase CBL.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.518
CBL	FGF3	A0A340X461	A0A340YJ84	E3 ubiquitin-protein ligase CBL.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.518
CBL	FGF4	A0A340X461	A0A340Y0L8	E3 ubiquitin-protein ligase CBL.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.518
CBL	FGF5	A0A340X461	M1PRC9	E3 ubiquitin-protein ligase CBL.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.518
CBL	FGF6	A0A340X461	A0A340Y770	E3 ubiquitin-protein ligase CBL.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.518
CBL	FGF8	A0A340X461	A0A340YDC6	E3 ubiquitin-protein ligase CBL.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.518