STRINGSTRING
NCBP1 NCBP1 FGFBP3 FGFBP3 POLR2I POLR2I LOC103078733 LOC103078733 TIAL1 TIAL1 PTPN11 PTPN11 POLR2H POLR2H FGFR2 FGFR2 FGF2 FGF2 LOC103087252 LOC103087252 LOC103076597 LOC103076597 FGF1 FGF1 BRAF BRAF POLR2C POLR2C LOC103089049 LOC103089049 HRAS HRAS PIK3CA PIK3CA NCBP2 NCBP2 FNDC3B FNDC3B SPRY2 SPRY2 GTF2F2 GTF2F2 FNDC3A FNDC3A RPS27A RPS27A FGF9 FGF9 FRS2 FRS2 MKNK1 MKNK1 LOC103087776 LOC103087776 NRAS NRAS LOC103076205 LOC103076205 LOC103080712 LOC103080712 PPP2CA PPP2CA POLR2G POLR2G UBA52 UBA52 ESRP2 ESRP2 MKNK2 MKNK2 HNRNPM HNRNPM UBB UBB PTBP2 PTBP2 CSDE1 CSDE1 FGF10 FGF10 PTBP1 PTBP1 POLR2D POLR2D GTF2F1 GTF2F1 FGF22 FGF22 POLR2E POLR2E RBFOX2 RBFOX2 SHC1 SHC1 LOC103076816 LOC103076816 POLR2A POLR2A POLR2B POLR2B PIK3R1 PIK3R1 GRB2 GRB2 LOC103072950 LOC103072950 CBL CBL ESRP1 ESRP1 FGF7 FGF7 MAPK3 MAPK3 POLR2F POLR2F LOC103076695 LOC103076695 LOC103076438 LOC103076438 TIA1 TIA1 PTBP3 PTBP3 LOC103083100 LOC103083100 UBC UBC MAPK1 MAPK1 ERAS ERAS FGFBP1 FGFBP1 PPP2CB PPP2CB LOC103078712 LOC103078712 LOC103083434 LOC103083434 LOC103076769 LOC103076769 SOS1 SOS1 SRC SRC KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCBP1Nuclear cap-binding protein subunit 1-like. (299 aa)
FGFBP3Fibroblast growth factor-binding protein 3. (255 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (132 aa)
LOC103078733Heterogeneous nuclear ribonucleoprotein A1-like. (320 aa)
TIAL1Nucleolysin TIAR isoform X1. (392 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
FGFR2Fibroblast growth factor receptor. (839 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (373 aa)
LOC103087252DNA-directed RNA polymerase II subunit RPB11-like. (117 aa)
LOC103076597ubiquitin-40S ribosomal protein S27a-like. (187 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (189 aa)
BRAFSerine/threonine-protein kinase B-raf. (763 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3. (275 aa)
LOC103089049DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (2732 aa)
HRASGTPase HRas isoform X1. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
SPRY2Protein sprouty homolog 2 isoform X1. (315 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
MKNK1MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1; Belongs to the protein kinase superfamily. (435 aa)
LOC103087776Sialidase-like. (251 aa)
NRASGTPase NRas. (189 aa)
LOC103076205Nuclear cap-binding protein subunit 1-like. (488 aa)
LOC103080712Heterogeneous nuclear ribonucleoprotein A1-like. (267 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (199 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
ESRP2Epithelial splicing regulatory protein 2. (717 aa)
MKNK2MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. (463 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M isoform X1. (730 aa)
UBBpolyubiquitin-C isoform X1. (305 aa)
PTBP2Polypyrimidine tract-binding protein 2 isoform X1. (537 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (843 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
PTBP1Polypyrimidine tract-binding protein 1 isoform X2. (560 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (142 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (516 aa)
FGF22LOW QUALITY PROTEIN: fibroblast growth factor 22; Belongs to the heparin-binding growth factors family. (229 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
RBFOX2RNA binding protein fox-1 homolog 2 isoform X1. (459 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
LOC103076816Heterogeneous nuclear ribonucleoprotein A1-like. (320 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
LOC103072950Uncharacterized protein LOC103072950. (442 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
ESRP1Epithelial splicing regulatory protein 1 isoform X3. (688 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
MAPK3Mitogen-activated protein kinase. (325 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
LOC103076695Uncharacterized protein LOC103076695. (373 aa)
LOC103076438ubiquitin-40S ribosomal protein S27a-like. (155 aa)
TIA1Nucleolysin TIA-1 isoform p40 isoform X1. (386 aa)
PTBP3Polypyrimidine tract-binding protein 3 isoform X2. (524 aa)
LOC103083100ubiquitin-60S ribosomal protein L40-like. (116 aa)
UBCpolyubiquitin-C. (462 aa)
MAPK1Mitogen-activated protein kinase 1 isoform X1. (263 aa)
ERASGTPase ERas. (233 aa)
FGFBP1Fibroblast growth factor-binding protein 1. (237 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
LOC103078712Heterogeneous nuclear ribonucleoprotein A1-like. (328 aa)
LOC103083434DNA-directed RNA polymerases I, II, and III subunit RPABC5-like. (81 aa)
LOC103076769Heterogeneous nuclear ribonucleoprotein A1-like. (333 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
SRCTyrosine-protein kinase. (548 aa)
KRASGTPase KRas. (188 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.