STRINGSTRING
UBB UBB SH3GL3 SH3GL3 LRIG1 LRIG1 PTPN1 PTPN1 MET MET UBC UBC LOC103083100 LOC103083100 LOC103076438 LOC103076438 PTPRJ PTPRJ CBL CBL LOC103072950 LOC103072950 GRB2 GRB2 USP8 USP8 SH3GL1 SH3GL1 STAM STAM EPS15 EPS15 UBA52 UBA52 PTPN2 PTPN2 HGS HGS STAM2 STAM2 RPS27A RPS27A SH3GL2 SH3GL2 HGF HGF LOC103076597 LOC103076597 SH3KBP1 SH3KBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBBpolyubiquitin-C isoform X1. (305 aa)
SH3GL3endophilin-A3. (347 aa)
LRIG1Leucine-rich repeats and immunoglobulin-like domains protein 1. (1110 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (440 aa)
METHepatocyte growth factor receptor isoform X1. (1412 aa)
UBCpolyubiquitin-C. (462 aa)
LOC103083100ubiquitin-60S ribosomal protein L40-like. (116 aa)
LOC103076438ubiquitin-40S ribosomal protein S27a-like. (155 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta-like. (1155 aa)
CBLE3 ubiquitin-protein ligase CBL. (910 aa)
LOC103072950Uncharacterized protein LOC103072950. (442 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
USP8LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 8; Belongs to the peptidase C19 family. (1116 aa)
SH3GL1endophilin-A2 isoform X1. (369 aa)
STAMSignal transducing adapter molecule 1. (507 aa)
EPS15Epidermal growth factor receptor substrate 15. (902 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type 2. (289 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
STAM2Signal transducing adapter molecule 2 isoform X1. (526 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
SH3GL2endophilin-A1. (352 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
LOC103076597ubiquitin-40S ribosomal protein S27a-like. (187 aa)
SH3KBP1SH3 domain-containing kinase-binding protein 1 isoform X1. (665 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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