STRINGSTRING
MCM2 MCM2 ANAPC10 ANAPC10 FAM89A FAM89A PSMA6 PSMA6 PSMD3 PSMD3 PSMD13 PSMD13 LOC103089645 LOC103089645 PSMD10 PSMD10 RPS27A RPS27A LOC103081970 LOC103081970 PSMF1 PSMF1 LOC103081704 LOC103081704 LOC103080427 LOC103080427 KPNB1 KPNB1 LOC103081255 LOC103081255 LOC103079884 LOC103079884 UBE2D1 UBE2D1 KPNA5 KPNA5 PSMC5 PSMC5 LOC103072950 LOC103072950 LOC103072393 LOC103072393 MCM9 MCM9 PSMB2 PSMB2 LOC103086067 LOC103086067 PSMC3 PSMC3 LOC103074048 LOC103074048 PSME1 PSME1 LOC103079983 LOC103079983 PSMD6 PSMD6 PSMB1 PSMB1 PSMB10 PSMB10 PSMB6 PSMB6 LOC103090400 LOC103090400 GMNN GMNN PSMC4 PSMC4 MCM5 MCM5 LOC103068806 LOC103068806 LOC103082498 LOC103082498 PSMD14 PSMD14 PSMD4 PSMD4 PSMB4 PSMB4 PSMB8 PSMB8 ORC1 ORC1 KXD1 KXD1 ANAPC2 ANAPC2 CDC23 CDC23 PSMA1 PSMA1 PSMA7 PSMA7 UBB UBB FZR1 FZR1 ANAPC15 ANAPC15 UBA52 UBA52 PSMB9 PSMB9 PSMD1 PSMD1 MCM4 MCM4 FAM89B FAM89B PSMC6 PSMC6 ANAPC5 ANAPC5 TM7SF3 TM7SF3 ANAPC4 ANAPC4 PSME2 PSME2 LOC103091442 LOC103091442 KPNA1 KPNA1 CDC26 CDC26 PSME3 PSME3 PSMB7 PSMB7 LOC103071163 LOC103071163 UBC UBC PSMD9 PSMD9 ANAPC7 ANAPC7 LOC103083100 LOC103083100 PSMB5 PSMB5 LOC103070340 LOC103070340 LOC103071706 LOC103071706 PSMA5 PSMA5 LOC103071989 LOC103071989 LOC103073911 LOC103073911 PSMD5 PSMD5 MCM3 MCM3 LOC103074978 LOC103074978 ORC6 ORC6 LOC103076438 LOC103076438 UBE2C UBE2C MCM6 MCM6 ORC4 ORC4 PSMD11 PSMD11 ANAPC16 ANAPC16 LOC103080676 LOC103080676 LOC103085965 LOC103085965 LOC103077443 LOC103077443 PSMD8 PSMD8 LOC103090291 LOC103090291 PSMC1 PSMC1 LOC103089763 LOC103089763 LOC103088445 LOC103088445 LOC103081931 LOC103081931 LOC103080666 LOC103080666 LOC103076624 LOC103076624 LOC103074679 LOC103074679 LOC103086798 LOC103086798 LOC103080928 LOC103080928 LOC103076894 LOC103076894 ANAPC1 ANAPC1 PSMA4 PSMA4 LOC103072472 LOC103072472 LOC103088169 LOC103088169 LOC103082925 LOC103082925 LOC103081667 LOC103081667 LOC103079101 LOC103079101 LOC103077708 LOC103077708 LOC103076354 LOC103076354 ORC2 ORC2 KPNA6 KPNA6 LOC103068676 LOC103068676 PSMA2 PSMA2 MCM7 MCM7 LOC103068403 LOC103068403 UBE2E1 UBE2E1 UBE2S UBE2S MCM8 MCM8 LOC103076597 LOC103076597 PSMC2 PSMC2 CDT1 CDT1 CDC16 CDC16 ORC5 ORC5 PSMA3 PSMA3 TM4SF19 TM4SF19 LOC103069053 LOC103069053 ORC3 ORC3 CDC6 CDC6 PSMB3 PSMB3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM2DNA helicase; Belongs to the MCM family. (991 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
FAM89AProtein FAM89A. (178 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13 isoform X1. (376 aa)
LOC103089645Histone H2A; Belongs to the histone H2A family. (128 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
LOC103081970Histone H2A; Belongs to the histone H2A family. (129 aa)
PSMF1Proteasome inhibitor PI31 subunit. (270 aa)
LOC103081704Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103080427Histone H2B; Belongs to the histone H2B family. (126 aa)
KPNB1Importin subunit beta-1 isoform X1. (805 aa)
LOC103081255Histone H2B; Belongs to the histone H2B family. (142 aa)
LOC103079884Histone H2A; Belongs to the histone H2A family. (130 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
KPNA5Importin subunit alpha; Functions in nuclear protein import. (536 aa)
PSMC526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (406 aa)
LOC103072950Uncharacterized protein LOC103072950. (442 aa)
LOC103072393Origin recognition complex subunit 6-like. (264 aa)
MCM9DNA helicase MCM9; Belongs to the MCM family. (1144 aa)
PSMB2Proteasome subunit beta. (201 aa)
LOC103086067Uncharacterized protein LOC103086067. (363 aa)
PSMC326S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (423 aa)
LOC103074048Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (134 aa)
PSME1Proteasome activator complex subunit 1 isoform X1. (249 aa)
LOC103079983Histone H2A; Belongs to the histone H2A family. (128 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (389 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMB6Proteasome subunit beta. (239 aa)
LOC103090400Histone H2B; Belongs to the histone H2B family. (126 aa)
GMNNGeminin. (183 aa)
PSMC426S protease regulatory subunit 6B isoform X1; Belongs to the AAA ATPase family. (418 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
LOC103068806Cell division cycle protein 27 homolog isoform X1. (852 aa)
LOC10308249826S proteasome non-ATPase regulatory subunit 12-like isoform X1. (456 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (310 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4. (377 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMB8Proteasome subunit beta. (276 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (859 aa)
KXD1kxDL motif-containing protein 1. (176 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (820 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
PSMA1Proteasome subunit alpha type. (263 aa)
PSMA7Proteasome subunit alpha type. (255 aa)
UBBpolyubiquitin-C isoform X1. (305 aa)
FZR1Fizzy-related protein homolog isoform X1. (511 aa)
ANAPC15Anaphase-promoting complex subunit 15 isoform X1. (160 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
MCM4DNA helicase; Belongs to the MCM family. (865 aa)
FAM89BProtein FAM89B isoform X1. (192 aa)
PSMC626S protease regulatory subunit 10B; Belongs to the AAA ATPase family. (403 aa)
ANAPC5Anaphase-promoting complex subunit 5 isoform X1. (755 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa)
PSME2Proteasome activator complex subunit 2. (239 aa)
LOC10309144226S proteasome non-ATPase regulatory subunit 7-like. (322 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
CDC26Anaphase-promoting complex subunit CDC26. (85 aa)
PSME3Proteasome activator complex subunit 3 isoform X1. (272 aa)
PSMB7Proteasome subunit beta. (277 aa)
LOC103071163Histone H2B; Belongs to the histone H2B family. (126 aa)
UBCpolyubiquitin-C. (462 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
ANAPC7LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7. (596 aa)
LOC103083100ubiquitin-60S ribosomal protein L40-like. (116 aa)
PSMB5Proteasome subunit beta. (263 aa)
LOC103070340Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103071706Histone H2A; Belongs to the histone H2A family. (130 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
LOC103071989Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103073911Histone H2B; Belongs to the histone H2B family. (126 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5 isoform X1. (504 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
LOC103074978Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ORC6Origin recognition complex subunit 6. (252 aa)
LOC103076438ubiquitin-40S ribosomal protein S27a-like. (155 aa)
UBE2CUbiquitin-conjugating enzyme E2 C isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
MCM6DNA helicase; Belongs to the MCM family. (829 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
ANAPC16Anaphase-promoting complex subunit 16. (110 aa)
LOC103080676Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC103085965Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103077443Histone H2A; Belongs to the histone H2A family. (130 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
LOC103090291Anaphase-promoting complex subunit 11-like. (84 aa)
PSMC126S protease regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
LOC103089763Uncharacterized protein LOC103089763. (411 aa)
LOC103088445Histone H2A; Belongs to the histone H2A family. (117 aa)
LOC103081931Histone H3; Belongs to the histone H3 family. (150 aa)
LOC103080666Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103076624Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103074679Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC103086798Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103080928Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC103076894Histone H2B; Belongs to the histone H2B family. (126 aa)
ANAPC1Anaphase-promoting complex subunit 1-like. (1944 aa)
PSMA4Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (311 aa)
LOC103072472Proteasome activator complex subunit 2-like. (239 aa)
LOC103088169Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC103082925Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103081667Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC103079101Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC103077708Histone H3; Belongs to the histone H3 family. (136 aa)
LOC103076354Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ORC2Origin recognition complex subunit 2 isoform X1. (577 aa)
KPNA6Importin subunit alpha; Functions in nuclear protein import. (543 aa)
LOC103068676Histone H2B type W-T-like; Belongs to the histone H2B family. (177 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
LOC103068403Histone H2B type W-T-like; Belongs to the histone H2B family. (184 aa)
UBE2E1Ubiquitin-conjugating enzyme E2 E1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
UBE2SUbiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa)
MCM8DNA helicase MCM8 isoform X1; Belongs to the MCM family. (832 aa)
LOC103076597ubiquitin-40S ribosomal protein S27a-like. (187 aa)
PSMC2LOW QUALITY PROTEIN: 26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (477 aa)
CDT1DNA replication factor Cdt1. (548 aa)
CDC16Cell division cycle protein 16 homolog isoform X1. (620 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
TM4SF19Transmembrane 4 L6 family member 19. (333 aa)
LOC103069053Anaphase-promoting complex subunit 11-like. (84 aa)
ORC3Origin recognition complex subunit 3 isoform X1. (714 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (560 aa)
PSMB3Proteasome subunit beta. (205 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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