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ADPRHL2 | poly(ADP-ribose) glycohydrolase ARH3. (365 aa) | ||||
LOC103074048 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (134 aa) | ||||
LOC103080676 | Histone H2A; Belongs to the histone H2A family. (129 aa) | ||||
ATAD5 | LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 5. (1898 aa) | ||||
POLE4 | DNA polymerase epsilon subunit 4. (116 aa) | ||||
TDG | G/T mismatch-specific thymine DNA glycosylase isoform X1. (405 aa) | ||||
MEIOB | Meiosis-specific with OB domain-containing protein isoform X1. (471 aa) | ||||
MPG | DNA-3-methyladenine glycosylase. (277 aa) | ||||
RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa) | ||||
POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2283 aa) | ||||
POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa) | ||||
RFC5 | Replication factor C subunit 5. (342 aa) | ||||
ACD | Adrenocortical dysplasia protein homolog. (454 aa) | ||||
LOC103090400 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
XRCC1 | DNA repair protein XRCC1. (628 aa) | ||||
VWA5B1 | LOW QUALITY PROTEIN: von Willebrand factor A domain-containing protein 5B1. (1226 aa) | ||||
MBD4 | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. (570 aa) | ||||
APEX2 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (514 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) | ||||
PNKP | Bifunctional polynucleotide phosphatase/kinase. (521 aa) | ||||
APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (320 aa) | ||||
TERF2IP | Telomeric repeat-binding factor 2-interacting protein 1. (399 aa) | ||||
PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa) | ||||
LIG1 | DNA ligase. (921 aa) | ||||
LOC103079884 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
LOC103081255 | Histone H2B; Belongs to the histone H2B family. (142 aa) | ||||
PARP2 | Poly [ADP-ribose] polymerase. (591 aa) | ||||
RFC3 | Replication factor C subunit 3. (356 aa) | ||||
POLD1 | DNA polymerase. (1107 aa) | ||||
LOC103080427 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC103081704 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC103081970 | Histone H2A; Belongs to the histone H2A family. (129 aa) | ||||
LOC103089645 | Histone H2A; Belongs to the histone H2A family. (128 aa) | ||||
RCBTB1 | RCC1 and BTB domain-containing protein 1. (531 aa) | ||||
RCBTB2 | RCC1 and BTB domain-containing protein 2 isoform X1. (572 aa) | ||||
SMUG1 | Single-strand selective monofunctional uracil DNA glycosylase. (271 aa) | ||||
LOC103068403 | Histone H2B type W-T-like; Belongs to the histone H2B family. (184 aa) | ||||
LOC103068676 | Histone H2B type W-T-like; Belongs to the histone H2B family. (177 aa) | ||||
RFC2 | Replication factor C subunit 2 isoform X1. (352 aa) | ||||
VWA5B2 | Von Willebrand factor A domain-containing protein 5B2. (1255 aa) | ||||
LOC103076354 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
LOC103079101 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC103081667 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
LOC103082925 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC103088169 | Histone H2B; Belongs to the histone H2B family. (127 aa) | ||||
NEIL2 | Endonuclease 8-like 2. (338 aa) | ||||
LOC103076894 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC103080928 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
LOC103086798 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC103074679 | Histone H2B; Belongs to the histone H2B family. (127 aa) | ||||
LOC103076624 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC103080666 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC103088445 | Histone H2A; Belongs to the histone H2A family. (117 aa) | ||||
LOC103077443 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
LOC103085965 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
PARP3 | Poly [ADP-ribose] polymerase. (536 aa) | ||||
TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (437 aa) | ||||
OGG1 | LOW QUALITY PROTEIN: N-glycosylase/DNA lyase. (318 aa) | ||||
NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (304 aa) | ||||
RFC4 | Replication factor C subunit 4. (364 aa) | ||||
MUTYH | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (524 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
LOC103074978 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
LOC103073911 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
LOC103071989 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
TERF2 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (539 aa) | ||||
LOC103071706 | Histone H2A; Belongs to the histone H2A family. (130 aa) | ||||
LOC103070340 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
POLE3 | DNA polymerase epsilon subunit 3. (147 aa) | ||||
RPA3 | Replication protein A 14 kDa subunit. (121 aa) | ||||
POLD4 | DNA polymerase delta subunit 4. (107 aa) | ||||
LOC103071163 | Histone H2B; Belongs to the histone H2B family. (126 aa) | ||||
POT1 | Protection of telomeres protein 1. (785 aa) | ||||
UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (312 aa) | ||||
POLD3 | DNA polymerase delta subunit 3. (469 aa) | ||||
TINF2 | TERF1-interacting nuclear factor 2. (453 aa) | ||||
RFC1 | Replication factor C subunit 1. (1245 aa) | ||||
LOC103079800 | Meiotic recombination protein REC114-like. (265 aa) | ||||
POLD2 | DNA polymerase delta subunit 2 isoform X1. (469 aa) | ||||
PARG | poly(ADP-ribose) glycohydrolase isoform X1. (975 aa) | ||||
LOC103074354 | Probable DNA-3-methyladenine glycosylase-like. (203 aa) | ||||
LOC103079983 | Histone H2A; Belongs to the histone H2A family. (128 aa) | ||||
LOC103089030 | Uncharacterized protein LOC103089030. (299 aa) | ||||
NEIL1 | Endonuclease 8-like 1. (390 aa) | ||||
LIG3 | DNA ligase. (1013 aa) | ||||
POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) | ||||
NEIL3 | Endonuclease 8-like 3. (606 aa) |