10 items (Lipotes vexillifer) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOS1	Son of sevenless homolog 1. (1333 aa)
	GRB10	Growth factor receptor-bound protein 10 isoform X1. (588 aa)
	MAPK1	Mitogen-activated protein kinase 1 isoform X1. (263 aa)
	IRS2	Insulin receptor substrate 2. (1362 aa)
	MAPK3	Mitogen-activated protein kinase. (325 aa)
	GRB2	Growth factor receptor-bound protein 2 isoform X1. (217 aa)
	SHC1	SHC-transforming protein 1 isoform X1. (584 aa)
	INSR	Tyrosine-protein kinase receptor. (1382 aa)
	INS	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	IRS1	Insulin receptor substrate 1. (1252 aa)

Your Current Organism:

Lipotes vexillifer

NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRB10	GRB2	A0A340WFM7	A0A340X5P7	Growth factor receptor-bound protein 10 isoform X1.	Growth factor receptor-bound protein 2 isoform X1.	0.657
GRB10	INS	A0A340WFM7	A0A340Y3F2	Growth factor receptor-bound protein 10 isoform X1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.766
GRB10	INSR	A0A340WFM7	A0A340XGU4	Growth factor receptor-bound protein 10 isoform X1.	Tyrosine-protein kinase receptor.	0.988
GRB10	IRS1	A0A340WFM7	A0A340Y3Y3	Growth factor receptor-bound protein 10 isoform X1.	Insulin receptor substrate 1.	0.655
GRB10	IRS2	A0A340WFM7	A0A340WRA4	Growth factor receptor-bound protein 10 isoform X1.	Insulin receptor substrate 2.	0.545
GRB2	GRB10	A0A340X5P7	A0A340WFM7	Growth factor receptor-bound protein 2 isoform X1.	Growth factor receptor-bound protein 10 isoform X1.	0.657
GRB2	INS	A0A340X5P7	A0A340Y3F2	Growth factor receptor-bound protein 2 isoform X1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.718
GRB2	INSR	A0A340X5P7	A0A340XGU4	Growth factor receptor-bound protein 2 isoform X1.	Tyrosine-protein kinase receptor.	0.969
GRB2	IRS1	A0A340X5P7	A0A340Y3Y3	Growth factor receptor-bound protein 2 isoform X1.	Insulin receptor substrate 1.	0.996
GRB2	IRS2	A0A340X5P7	A0A340WRA4	Growth factor receptor-bound protein 2 isoform X1.	Insulin receptor substrate 2.	0.985
GRB2	MAPK1	A0A340X5P7	A0A340WNH5	Growth factor receptor-bound protein 2 isoform X1.	Mitogen-activated protein kinase 1 isoform X1.	0.592
GRB2	MAPK3	A0A340X5P7	A0A340WYU9	Growth factor receptor-bound protein 2 isoform X1.	Mitogen-activated protein kinase.	0.448
GRB2	SHC1	A0A340X5P7	A0A340X9E5	Growth factor receptor-bound protein 2 isoform X1.	SHC-transforming protein 1 isoform X1.	0.999
GRB2	SOS1	A0A340X5P7	A0A340WF86	Growth factor receptor-bound protein 2 isoform X1.	Son of sevenless homolog 1.	0.999
INS	GRB10	A0A340Y3F2	A0A340WFM7	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Growth factor receptor-bound protein 10 isoform X1.	0.766
INS	GRB2	A0A340Y3F2	A0A340X5P7	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Growth factor receptor-bound protein 2 isoform X1.	0.718
INS	INSR	A0A340Y3F2	A0A340XGU4	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.999
INS	IRS1	A0A340Y3F2	A0A340Y3Y3	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin receptor substrate 1.	0.982
INS	IRS2	A0A340Y3F2	A0A340WRA4	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin receptor substrate 2.	0.979
INS	SHC1	A0A340Y3F2	A0A340X9E5	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	SHC-transforming protein 1 isoform X1.	0.558