STRINGSTRING
GAB2 GAB2 SHC1 SHC1 LDB3 LDB3 PRKACB PRKACB NRTN NRTN DOK6 DOK6 PRKACA PRKACA PIK3CA PIK3CA FNDC3B FNDC3B PIK3CB PIK3CB FNDC3A FNDC3A ARTN ARTN GFRA1 GFRA1 DOK4 DOK4 GFRA2 GFRA2 PIK3CD PIK3CD PRKCA PRKCA SHANK3 SHANK3 GRB2 GRB2 RAP1GAP RAP1GAP DOK1 DOK1 NXPE2 NXPE2 PSPN PSPN PIK3R2 PIK3R2 GFRA3 GFRA3 PLCG1 PLCG1 GRB7 GRB7 PDLIM7 PDLIM7 GFRA4 GFRA4 FRS2 FRS2 GAB1 GAB1 NXPE4 NXPE4 RET RET MAPK7 MAPK7 DOK2 DOK2 PDLIM5 PDLIM5 GRB10 GRB10 IRS2 IRS2 SOS1 SOS1 SRC SRC SHC3 SHC3 PIK3R3 PIK3R3 PTPN11 PTPN11 GDNF GDNF PIK3R1 PIK3R1 DOK5 DOK5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GAB2GRB2-associated-binding protein 2. (640 aa)
SHC1SHC-transforming protein 1 isoform X1. (584 aa)
LDB3LIM domain-binding protein 3 isoform X1. (721 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta. (274 aa)
NRTNNeurturin. (197 aa)
DOK6Docking protein 6. (331 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily. (351 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1073 aa)
FNDC3BFibronectin type III domain-containing protein 3B. (1206 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1064 aa)
FNDC3AFibronectin type-III domain-containing protein 3A isoform X1. (1198 aa)
ARTNArtemin. (238 aa)
GFRA1GDNF family receptor alpha; Belongs to the GDNFR family. (468 aa)
DOK4Docking protein 4. (326 aa)
GFRA2GDNF family receptor alpha; Belongs to the GDNFR family. (464 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1003 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
SHANK3SH3 and multiple ankyrin repeat domains protein 3. (1586 aa)
GRB2Growth factor receptor-bound protein 2 isoform X1. (217 aa)
RAP1GAPRap1 GTPase-activating protein 1 isoform X1. (727 aa)
DOK1Docking protein 1 isoform X1. (483 aa)
NXPE2LOW QUALITY PROTEIN: NXPE family member 2. (595 aa)
PSPNPersephin. (181 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (724 aa)
GFRA3GDNF family receptor alpha-3. (399 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
GRB7LOW QUALITY PROTEIN: growth factor receptor-bound protein 7. (557 aa)
PDLIM7PDZ and LIM domain protein 7 isoform X1. (458 aa)
GFRA4GDNF family receptor alpha-4. (269 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
GAB1GRB2-associated-binding protein 1 isoform X1. (723 aa)
NXPE4LOW QUALITY PROTEIN: neurexophilin and PC-esterase domain family, member 4. (471 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1026 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (774 aa)
DOK2Docking protein 2. (411 aa)
PDLIM5PDZ and LIM domain protein 5 isoform X1. (337 aa)
GRB10Growth factor receptor-bound protein 10 isoform X1. (588 aa)
IRS2Insulin receptor substrate 2. (1362 aa)
SOS1Son of sevenless homolog 1. (1333 aa)
SRCTyrosine-protein kinase. (548 aa)
SHC3SHC-transforming protein 3. (588 aa)
PIK3R3LOW QUALITY PROTEIN: phosphatidylinositol 3-kinase regulatory subunit gamma. (480 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
GDNFGlial cell line-derived neurotrophic factor isoform X1. (211 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
DOK5Docking protein 5. (306 aa)
Your Current Organism:
Lipotes vexillifer
NCBI taxonomy Id: 118797
Other names: L. vexillifer, Yangtze River dolphin, baiji
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